Peptide P3 ameliorates foam cell formation in RAW264.7 cells and its molecular mechanisms
- Author:
Jia-Hui LI
1
;
Yu-Heng JIANG
1
;
Cheng-Jin WANG
1
;
Lin JIANG
1
;
Yan DENG
1
;
Li-Lin ZHANG
1
;
Qing-Zhong XU
1
;
Hong-Mei LI
1
Author Information
- Publication Type:Journal Article
- Keywords: ATP-binding cassette transporter A1; ATP-binding cassette transporter G1; foam cells; lipid accumulation; liver X receptor; peptide P3; RAW264.7 cells
- From: Chinese Pharmacological Bulletin 2023;39(9):1711-1717
- CountryChina
- Language:Chinese
- Abstract: Aim To examine the effect of peptide P3 on lipid accumulation in RAW264.7 cells and the underlying molecular mechanism. Methods MTT method was used to screen the concentration of peptide P3 and oxidized low density lipoprotein(ox-LDL),and RAW.264.7 cells were induced to form foam cells by ox-LDL with 80 mg·L
