Research progress of corneal lymphangiogenesis in ocular diseases
10.3980/j.issn.1672-5123.2024.4.08
- VernacularTitle:角膜淋巴管新生在眼部疾病中的研究进展
- Author:
Mengjie LI
1
;
Yuying ZHU
1
;
Jiange ZHANG
1
Author Information
1. The Research Center of Chiral Drugs, Innovation Research Institute of Traditional Chinese Medicine(IRI), Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
- Publication Type:Journal Article
- Keywords:
cornea;
lymphangiogenesis;
lymphangiogenic factors;
ocular diseases;
dry eye disease
- From:
International Eye Science
2024;24(4):539-544
- CountryChina
- Language:Chinese
-
Abstract:
Corneal lymphangiogenesis plays a crucial role in ocular diseases. Normally, the cornea lacks blood vessels and lymph vessels, which are essential for maintaining transparency and function of cornea. However, certain diseases or injuries will prompt angiogenesis and lymphangiogenesis in cornea, thus disrupting the structure and function of cornea. Although various drugs targeting corneal angiogenesis have been applied in clinical practice, there is still a gap in medications targeting corneal lymphangiogenesis. Therefore, this review will introduce the factors related to corneal lymphangiogenesis, introduce related ocular diseases, and analyze the current treatment status, which will provide more options and possibilities for the treatment of lymphangiogenesis in ocular diseases and provide guidance for future research and drug development.
