Research progress in the effectiveness and mechanism of hyperbaric oxygen therapy for depression
10.11886/scjsws20230208003
- VernacularTitle:高压氧治疗抑郁症的效果及机制研究进展
- Author:
Lin XIAO
1
;
Xiaomei ZHANG
2
;
Kai WU
3
;
Lu WANG
1
Author Information
1. The Fourth People's Hospital of Chengdu， Chengdu 610036， China
2. University of Electronic Science and Technology of China， Chengdu 611731， China
3. Wenjiang District People's Hospital of Chengdu， Chengdu 611130， China
- Publication Type:Journal Article
- Keywords:
Hyperbaric oxygen;
Depression;
Neuroinflammation;
Synaptic plasticity
- From:
Sichuan Mental Health
2024;37(1):91-96
- CountryChina
- Language:Chinese
-
Abstract:
Hyperbaric oxygen therapy characterized by fewer side effects and simple operation has been explored as a potential therapy for depression. This article provides a review of researches relevant to current clinical application and mechanism of hyperbaric oxygen therapy for depression， aiming to provide valuable references for the formulation of new strategies for the treatment of depression. Hyperbaric oxygen therapy has been demonstrated to be useful as an adjunctive therapy for depression， which can effectively alleviate depression by regulating the homeostasis of hypothalamus-pituitary-adrenal axis， inhibiting inflammation and enhancing synaptic plasticity. And hyperbaric oxygen therapy as adjuvant to antidepressants for depression can contribute to increasing the treatment effectiveness to some extent.
