Early Experience of Prostate Cancer Treated with CyberKnife(TM) Radiotherapy.
10.4111/kju.2009.50.11.1066
- Author:
Jae Ho HYUN
1
;
Byoung Hun PARK
;
Dae Yong KOO
;
Kang sup KIM
;
Ki Hak SONG
;
Won Kyu JEONG
;
Dong Seok HAN
;
Jin Bum KIM
;
Young Seop CHANG
Author Information
1. Department of Urology, College of Medicine, Konyang University, Daejeon, Korea. ovalboy@hanmail.net
- Publication Type:Original Article
- Keywords:
Prostatic neoplasms;
Prostate-specific antigen
- MeSH:
Biopsy;
Defecation;
Follow-Up Studies;
Humans;
Lymph Nodes;
Neoplasm Metastasis;
Prostate;
Prostate-Specific Antigen;
Prostatic Neoplasms;
Recurrence
- From:Korean Journal of Urology
2009;50(11):1066-1072
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: We investigated the outcome in patients with prostatic cancer treated by means of CyberKnife(TM) radiotherapy. MATERIALS AND METHODS: Between July 2007 and April 2009, 16 patients with prostate cancer underwent CyberKnife(TM) radiotherapy. The histologic diagnosis was established by transrectal ultrasonography-guided biopsy. Radiotherapy was performed for a dose of 34 Gy at 8.5 Gy per day over 4 to 18 days. Nine patients were treated with hormone therapy. After treatment, prostate-specific antigen (PSA) relapse was evaluated with periodic PSA follow-up. RESULTS: The numbers of patients in clinical stages T2 and T3 were 13 and 3, respectively. Two patients had lymph node metastasis with no distant metastasis. The numbers of patients with a Gleason grade of 5, 6, 7, 8, and 9 were 1, 5, 4, 3, and 2, respectively. The mean time to PSA nadir and the mean PSA at nadir were 7 months and 0.43 ng/ml, respectively. To date, there has been no biochemical failure or clinical recurrence. No severe complications were observed in any patients; observed minor complications [n (%)] were perianal pain [2 (12.5%)] and defecation discomfort [2 (12.5%)]. CONCLUSIONS: Generally good responses were observed in patients treated with CyberKnife(TM) radiotherapy for prostate cancer. No severe complications were observed. More patients and a longer follow-up are required for further conclusions.
