Research Progress on Association Between Oral Bacteria and Gastric Cancer

VernacularTitle:口腔菌群与胃癌相关性的研究进展
Author: Ju ZHANG ¹ ; Qiang DONG ; Yongquan SHI
Author Information

1. State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and National Clinical Research Center for Digestive Diseases, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an 710032, China
Publication Type:Research Article
Keywords: Gastric cancer; Oral bacterium; Diagnosis; Biomarker
From: Cancer Research on Prevention and Treatment 2024;51(2):147-151
CountryChina
Language:Chinese
Abstract: Gastric cancer is one of the major types of cancer threatening human health worldwide. Its pathogenesis has not been fully elucidated, and patients are often diagnosed at an advanced stage. The oral cavity is the second largest microbial pool after the intestine in the human body, and thus the relationship between oral bacteria and human health is attracting increasing interest. Oral bacteria are closely related to gastric cancer and potentially serve as noninvasive diagnostic screening biomarkers for the disease. Imbalance in and displacement of these bacteria can promote the occurrence and development of gastric cancer. Hence, this article reviews the association between oral bacteria and gastric cancer, aiming to provide a basis for further elucidating the pathogenesis of gastric cancer and screening it early through noninvasive methods and serve as a reference for subsequent related research.