Two Cases of Anti-Jka Whose Reactivity Was Disappeared after Enzyme Treatment.
- Author:
Moon Suk CHOI
1
;
Yong Gon CHO
;
Jaehyeon LEE
;
Dal Sik KIM
;
Hye Soo LEE
;
Sam Im CHOI
Author Information
1. Department of Laboratory Medicine, Chonbuk National University Medical School, Jeonju, Korea. choyg@jbnu.ac.kr
- Publication Type:Case Report
- Keywords:
Anti-Jka;
Enzyme;
EDTA
- MeSH:
Aged;
Colonic Neoplasms;
Edetic Acid;
Female;
Fibrosis;
Humans;
Liver;
Middle Aged;
Phenotype
- From:Korean Journal of Blood Transfusion
2012;23(2):173-179
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report on two cases of anti-Jka, whose reactivity disappeared on an antibody identification test using enzyme-treated red cells. One of two patients was a 72-year-old female with cirrhosis of the liver and colon cancer, and the other was a 55-year-old female with known MDS and incomplete Behcet's disease. Results of an antibody identification test using a LISS/Coombs gel card (DiaMed AG) showed negative to one positive with red cells having the Jka antigen; however, all reactions using the enzyme-treated cells showed negative results, which was unexpected. The patients' RBC phenotype was Jk(a-b+). We obtained positive results in reactions of enzyme-treated Jka+ cells and EDTA using a patient's serum and proved that the cause of the negative reaction might be complement-related.
