Research progress on the manifestations and prognosis of neonatal lupus erythematosus in various systems
10.7499/j.issn.1008-8830.2306125
- VernacularTitle:新生儿红斑狼疮各系统表现及预后研究进展
- Author:
Shu-Ming SHAO
1
;
Yi-Min ZHANG
;
Xiao-Rui ZHANG
Author Information
1. 北京大学人民医院儿科,北京 100044
- Keywords:
Neonatal lupus erythematosus;
Clinical manifestation;
Prognosis
- From:
Chinese Journal of Contemporary Pediatrics
2024;26(1):81-85
- CountryChina
- Language:Chinese
-
Abstract:
Neonatal lupus erythematosus(NLE)is caused by the transmission of maternal anti-Ro/SSA antibodies,anti-La/SSB antibodies,and other autoantibodies to the fetus through the placenta.Usually,with the disappearance of autoantibodies in the children's body,abnormal changes in the mucocutaneous,blood system,and digestive system can spontaneously subside,but the damage to various systems caused by autoantibodies may persist for a long time.This article provides a comprehensive review of the manifestations and prognosis of NLE in various systems,including mucocutaneous,blood system,circulatory system,nervous system,digestive system,respiratory system,aiming to provide reference for clinical work.
