Correlation of traditional Chinese medicine to reduced re-admission risk in ankylosing spondylitis patients with dampness-heat syndrome: a retrospective cohort study.
10.19540/j.cnki.cjcmm.20230619.501
- Author:
Cheng-Zhi CONG
1
;
Jian LIU
2
;
Yue-di HU
2
;
Yang LI
1
;
Yi-Ming CHEN
1
;
Dan HUANG
2
Author Information
1. Anhui Province Hospital of Chinese Medicine Hefei 230031, China the First Clinical Medical College of Anhui University of Chinese Medicine Hefei 230022, China.
2. Anhui Province Hospital of Chinese Medicine Hefei 230031, China.
- Publication Type:Journal Article
- Keywords:
ankylosing spondylitis;
cohort study;
dampness-heat syndrome;
telephone follow-up;
traditional Chinese medicine
- MeSH:
Humans;
Medicine, Chinese Traditional;
Spondylitis, Ankylosing/epidemiology*;
Retrospective Studies;
Hot Temperature
- From:
China Journal of Chinese Materia Medica
2023;48(20):5651-5658
- CountryChina
- Language:Chinese
-
Abstract:
This study aimed to analyze the impact of traditional Chinese medicine(TCM) on the risk of re-admission for ankylosing spondylitis(AS) patients with dampness-heat syndrome. In this study, a telephone follow-up was conducted on 1 295 AS inpatients, and after screening and exclusions, 1 044 successfully followed-up patients were included. A retrospective cohort study was conducted using propensity score matching(PSM), and a Cox proportional risk model was employed to assess the effect of various factors on the risk of re-admission for AS patients with dampness-heat syndrome. Kaplan-Meier survival curves were used to analyze the effect of TCM intervention time on re-admission. The incidence rate of dampness-heat syndrome in AS patients was found to be 51.3% in this study. After 1∶1 PSM, 385 AS patients with dampness-heat syndrome and 385 AS patients without dampness-heat syndrome were included for analysis. The results indicated that the re-admission rate was higher for patients with dampness-heat syndrome compared with those without dampness-heat syndrome(P<0.05). AS patients with dampness-heat syndrome in the TCM group had a lower admission rate than those in the non-TCM group(P=0.01). The cox proportional risk model demonstrated that TCM was an independent protective factor, as it reduced the risk of re-admission by 35%(HR=0.35, 95%CI[0.26, 0.95], P<0.05). Moreover, the subgroup with high exposure(time to use Chinese medicine >12 months) had a significantly lower risk of re-admission than that with low TCM exposure(time to use Chinese medicine ≤12 months). The re-admission rate for AS patients with dampness-heat syndrome was higher than that without dampness-heat syndrome, and TCM was identified as a protective factor in reducing the risk of re-admission. Furthermore, a longer duration of TCM intervention was associated with a lower risk of re-admission.
