Comparison of chemical constituents in Artemisiae Argyi Folium from different Dao-di producing areas based on UPLC and HS-GC-MS.
10.19540/j.cnki.cjcmm.20230605.101
- Author:
Qian-Qian WANG
1
;
Rui GUO
1
;
Dan ZHANG
1
;
Yu-Guang ZHENG
2
;
Qian ZHENG
3
;
Long GUO
1
Author Information
1. Traditional Chinese Medicine Processing Technology Innovation Center of Hebei Province, Hebei University of Chinese Medicine Shijiazhuang 050200, China International Joint Research Center on Resource Utilization and Quality Evaluation of Traditional Chinese Medicine of Hebei Province, Hebei University of Chinese Medicine Shijiazhuang 050200, China.
2. Traditional Chinese Medicine Processing Technology Innovation Center of Hebei Province, Hebei University of Chinese Medicine Shijiazhuang 050200, China Hebei Chemical and Pharmaceutical College Shijiazhuang 050026, China.
3. Shijiazhuang Hospital of Traditional Chinese Medicine Shijiazhuang 050051, China.
- Publication Type:Journal Article
- Keywords:
Artemisiae Argyi Folium;
Dao-di producing areas;
chemometrics;
nonvolatile components;
volatile components
- MeSH:
Gas Chromatography-Mass Spectrometry;
Chromatography, High Pressure Liquid/methods*;
Drugs, Chinese Herbal/chemistry*;
Flavonoids/analysis*;
Plant Leaves/chemistry*;
Artemisia/chemistry*
- From:
China Journal of Chinese Materia Medica
2023;48(20):5509-5518
- CountryChina
- Language:Chinese
-
Abstract:
This study aims to compare the chemical constituents in 24 batches of Artemisiae Argyi Folium samples collected from three different Dao-di producing areas(Anguo in Hebei, Nanyang in Henan, and Qichun in Hubei). An ultra-performance liquid chromatography(UPLC) method was established to determine the content of 13 nonvolatile components, and headspace-gas chromatography-mass spectrometry(HS-GC-MS) was employed for qualitative analysis and comparison of the volatile components. The content of phenolic acids in Artemisiae Argyi Folium was higher than that of flavonoids, and the content of nonvolatile components showed no significant differences among the samples from the three Dao-di producing areas. A total of 40 volatile components were identified, and the relative content of volatile components in Artemisiae Argyi Folium was significantly different among the samples from different Dao-di producing areas. The principal component analysis and partial least squares discriminant analysis identified 8 volatile components as the potential markers for discrimination of Artemisiae Argyi Folium samples from different Dao-di producing areas. This study revealed the differences in the chemical composition of Artemisiae Argyi Folium samples from three different Dao-di producing areas, providing analytical methods and a scientific basis for the discrimination and quality evaluation of Artemisia Argyi Folium in different Dao-di producing areas.
