The applications of the plasma matrix in the treatments of dental pulp and periapical diseases
10.12016/j.issn.2096-1456.2024.02.001
- VernacularTitle:血浆基质在牙髓根尖周病治疗中的应用
- Author:
Xuechao YANG
1
;
Wenzhi LI
Author Information
1. 广州医科大学附属口腔医院牙体牙髓科·广东省口腔组织修复与重建工程技术中心·广州市口腔再生医学基础与应用研究重点实验室,广东 广州(510182)
- Keywords:
plasma matrix;
pulp revascularization;
pulp regeneration;
apical surgery;
repair of dental hard tissue;
apexification;
furcation perforation repair;
platelet-rich plasma;
platelet-rich fibrin;
concentrated growth factor
- From:
Journal of Prevention and Treatment for Stomatological Diseases
2024;32(2):81-88
- CountryChina
- Language:Chinese
-
Abstract:
The plasma matrix is a kind of autologous blood conduct.It has been widely used in maxillofacial tissue regeneration,skin cosmetology and some other fields.Recently,to preserve the dental pulp as well as the teeth,pulp re-generation therapy and apical surgery have become increasingly important as well as the applications of bioactive materi-als.As a kind of autologous bioactive material,the plasma matrix has some natural advantages as it is easy to obtain and malleable.The plasma matrix can be used in the following cases:①pulp revascularization of young permanent teeth with open apical foramina that cannot stimulate apical bleeding;② apical barrier surgery with bone defects and large ar-ea perforation repair with bone defects or root sidewall repair surgery;③ apical surgeries of teeth with large area of api-cal lesions,with or without periodontal diseases.The plasma matrix is a product derived from our blood,and there are no obvious contraindications for its use.Several systematic reviews have shown that the plasma matrix can effectively promote the regenerative repair of dental pulp in patients with periapical diseases.However,the applications of plasma matrix are different because its characteristics are affected by different preparation methods.In addition,there is still a lack of long-term clinical researches on the plasma matrix,and the histological evidences are difficult to obtain,so a large number of in vitro and in vivo experimental studies are still needed.This article will describe the applications of different kinds of plasma matrix for dental pulp regeneration and bone tissue regeneration in apical surgeries to provide references for clinicians in indication selection and prognosis evaluation.
