Clinical management strategies for recipients with renal graft loss
10.3969/j.issn.1674-7445.2023149
- VernacularTitle:移植肾功能丧失受者的临床管理策略
- Author:
Hao YANG
1
;
Jun LIN
1
;
Jian ZHANG
1
Author Information
1. Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
- Publication Type:ReviewArticle
- Keywords:
Kidney transplantation;
Renal graft loss;
Panel reactive antibody;
Immunosuppressive drugs;
Renal replacement therapy;
Sensitization;
Allograft nephrectomy;
Transcatheter vascular embolization
- From:
Organ Transplantation
2024;15(1):138-144
- CountryChina
- Language:Chinese
-
Abstract:
With the maturity of kidney transplantation, introduction of new immunosuppressive drugs and improvement of immunosuppressive regimen, the short-term survival rate of kidney transplant recipients has been significantly improved, whereas the long-term survival rate has not been significantly elevated. Kidney transplant recipients may have the risk of renal graft loss. Clinical management after renal graft loss is complicated, including the adjustment of immunosuppressive drugs, management of renal graft and selection of subsequent renal replacement therapy. These management procedures directly affect clinical prognosis of patients with renal graft loss. Nevertheless, relevant guidelines or consensuses are still lacking. Clinical management of patients after renal graft loss highly depend upon clinicians’ experience. In this article, the adjustment of immunosuppressive drugs, management of renal graft and selection of subsequent renal replacement therapy were reviewed, aiming to provide reference for prolonging the survival and improving the quality of life of these patients.
