Advances in the application of lyophilized platelets and derivative products
10.13303/j.cjbt.issn.1004-549x.2023.08.023
- VernacularTitle:冻干血小板及衍生制品应用的研究进展
- Author:
Wenjuan LI
1
;
Shuchao ZHANG
2
Author Information
1. Blood Transfusion Department, Chengwu County People's Hospital, Chengwu 274200, China; Department of Immunology, College of Basic Medicine, Qingdao University
2. Blood Transfusion Department, The Affiliated Hospital of Qingdao University; Department of Immunology, College of Basic Medicine, Qingdao University
- Publication Type:Journal Article
- Keywords:
lyophilized platelets;
hemorrhage;
wound healing;
tissue repairing
- From:
Chinese Journal of Blood Transfusion
2023;36(8):745-750
- CountryChina
- Language:Chinese
-
Abstract:
Platelets are important components of the blood system. There are many kinds of concentrated platelets and their derivatives, among which platelet-rich plasma (PRP ), growth factors (GFs) and platelet-rich fibrin (PRF) have been widely used in clinical practice. Lyophilized platelets (Lyo-P) or freeze-dried platelets (FDP) are prepared from concentrated platelets by freeze-drying and have the advantages of long storage time at room temperature, light weight, convenient transportation, inactivation of pathogens, etc. Lyo-P contain high concentration of GFs, fibrin, white blood cells and various cytokines. In addition to their hemostatic and coagulative functions, Lyo-P and their products are increasingly used in wound healing, tissue repair, cosmetology, reproductive medicine and other fields.
