Research progress on the correlation between blood donor factors and red blood cell storage lesion

VernacularTitle:献血者因素与红细胞储存损伤相关性的研究进展
Author: Hongyan LI ¹ ; Li HE ¹ ; Yongjun WANG ¹
Author Information

1. Department of Blood Transfusion, Second Xiangya Hospital, Central South University, Changsha 240000, China
Publication Type:Journal Article
Keywords: blood donors; RBCs; storage lesion
From: Chinese Journal of Blood Transfusion 2021;34(9):1046-1049
CountryChina
Language:Chinese
Abstract: Red blood cells (RBCs) storage lesion refers to a series of changes in physiology, biochemistry, metabolism, appearance and morphology of RBCs during in vitro storage. In recent years, studies showed that individual differences among donors, such as physiology, genetics, lifestyle and drug use, etc., can directly affect the efficacy of RBCs storage and infusion. This article reviews the research progress on the effect of blood donor factors on RBCs storage lesion, in order to provide reference for the safety of blood transfusion.