Study on the safety of homotype transfusion of military blood donors with negative unexpected antibodies
10.13303/j.cjbt.issn.1004-549x.2022.03.021
- VernacularTitle:军人献血者红细胞意外抗体阴性血液同型输注的安全性研究
- Author:
Yanchun ZHANG
1
;
Jing JIN
1
;
Tao WU
1
Author Information
1. The Seventh Medical Center of PLA General Hospital, Department of Blood Transfusion Medicine, Beijing 100700, China
- Publication Type:Journal Article
- Keywords:
negative unexpected antibody;
red blood cell;
military blood donors;
homotype transfusion;
antibody screening;
direct antiglobulin test;
cross-matching;
blood transfusion safety
- From:
Chinese Journal of Blood Transfusion
2022;35(3):314-316
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To analyze the safety of homotypic transfusion in military donors with negative unexpected antibody. 【Methods】 Blood samples (4 mL/person)of eligible military blood donors from November 2018 to October 2019 in our hospital (also working as forces blood station) were conducted for RBC antigen typing, unexpected antibody screening, direct antiglobulin test and cross-match test using microcolumn gel technology, and the compatibility of homotype blood samples was statistical analyzed. 【Results】 A total of 1 577 samples from eligible military blood donors were collected, including A RhD (+ ), B RhD (+ ), O RhD (+ ) and AB RhD (+ ), accounting for 31.39% (495/1 577), 34.37% (542/1 577), 24.10% (380/1 577) and 10.15% (160/1 577), respectively. Six samples presenting positive unexpected antibodies (0.38%, 6/1 577) were screened out, and a total of 7 141 cross-matching tests were performed on 1 571 unexpected antibody negative samples, including A RhD (+ ) [37.36% (2 668/7 141)], B RhD (+ ) [34.81% (2 486/7 141)], O RhD (+ ) [17.71% (1265/7 141)] and AB RhD (+ ) [10.11% (722/7 141)]. There was only 1 case of incompatible cross-matching presented between other donors and clinical patients, and the direct antiglobulin test was 1+ , therefore suspended red blood cells of the donor were scrapped. 【Conclusion】 There was high compatibility and good security of homotype transfusion of military blood donors with negative unexpected antibody.
