Mechanism and transfusion strategy of immunogenic platelet transfusion refractoriness
10.13303/j.cjbt.issn.1004-549x.2022.06.022
- VernacularTitle:免疫性血小板输注无效发生机制和解决策略
- Author:
Juan SAI
1
;
Li TIAN
1
Author Information
1. Key Laboratory of Transfusion Adverse Reactions, Chinese Academy of Medical Sciences, Institute of Blood Transfusion, Chinese Academy of Medical Sciences and Peking Union Medical College, Chengdu 610052, China
- Publication Type:Journal Article
- Keywords:
platelet transfusion refractoriness;
immunogenic factors;
mechanism;
transfusion strategy
- From:
Chinese Journal of Blood Transfusion
2022;35(6):677-682
- CountryChina
- Language:Chinese
-
Abstract:
Platelet transfusion is an irreplaceable method to treat patients with platelet reduction in Hematology Department and Oncology Department. However, immunogenic platelet transfusion refractoriness is a huge challenge to patients who require repeatedly platelet transfusion. Therefore, mechanisms and reasonable transfusion strategies should be formulated to improve immunogenic platelet transfusion outcomes. This article aims to review the research progress and prospects concerning mechanisms and solutions of immunogenic platelet transfusion refractoriness, and provide rational transfusion strategies for platelet transfusion refractoriness patients, thus improving platelet transfusion outcomes.
