Electrolyte changes induced by massive transfusion in patients undergoing cardiac surgery
10.13303/j.cjbt.issn.1004-549x.2022.06.005
- VernacularTitle:心脏手术患者大量输血后的血清电解质变化分析
- Author:
Xusheng CHEN
1
;
Yongtao YANG
1
Author Information
1. Department of Blood Transfusion, the First Affiliated Hospital of Tsinghua University, Beijing 100016, China
- Publication Type:Journal Article
- Keywords:
massive blood transfusion;
heart surgery;
serum electrolytes;
blood transfusion complications;
poor surgical healing
- From:
Chinese Journal of Blood Transfusion
2022;35(6):612-614
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To investigate the effect of electrolyte concentration on transfusion related complications in patients undergoing cardiac surgery after short-term massive transfusion (MT). 【Methods】 Seventy-six cases of adult cardiac surgery in our hospital from January 2018 to December 2019 were collected. According to their perioperative blood transfusion units, they were divided into the massive blood transfusion group (red blood cell units≥ 10 U/ person) and the control group[red blood cell units (0~1)U/ person]. The concentrations of Na+ , K+ and Ca2+ ions in serum were detected by ISE (ion selective electrode method) and NM-BAPTA before and after intraoperative blood transfusion. The changes of Na+ , K+ and Ca2+ ions in serum before and after intraoperative blood transfusion were analyzed and compared through T-test. 【Results】 There were 38 patients in the MT group and 38 in the control group, and the demographic variables and types of surgeries (number) of patients in the two groups were comparable (P>0.05). The serum K+ , Ca2+ and Na+ before operation were similar (P>0.05), and within the normal range. The mean values of serum K+ , Ca2+ and Na+ (mmol/l) in the massive blood transfusion group and the control after operation (blood transfusion) were 4.25±0.44 vs 4.01±0.53, 2.31±0.12 vs 2.45±0.43, 140.82±2.31 vs 146.44±4.35 (P<0.05). In the control, the serum K+ , and Ca2+ were slightly lower than those before operation, while the Na+ was slightly higher (all P>0.05), and all were within the normal range. 【Conclusion】 Patients undergoing cardiac surgery are prone to suffer electrolyte disorders after massive blood transfusion. Electrolyte concentration should be monitored in time during and after perioperative blood transfusion.
