Nailfold capillaroscopy findings of interstitial pneumonia with autoimmune features
- Author:
Sang-Heon LEE
1
;
Hong Ki MIN
;
Se-Hee KIM
;
Young Whan KIM
;
Kwang Ha YOO
;
Hee Joung KIM
;
In Ae KIM
;
Hae-Rim KIM
Author Information
- Publication Type:2
- From:The Korean Journal of Internal Medicine 2023;38(6):903-911
- CountryRepublic of Korea
- Language:English
-
Abstract:
Background/Aims:We evaluated nailfold capillaroscopy (NFC) of interstitial pneumonia with autoimmune features (IPAF) and compared it with that of patients with connective tissue disease-interstitial lung disease (CTD-ILD) and idiopathic interstitial pneumonia (IIP).
Methods:Patients with newly diagnosed as ILD were evaluated using NFC. Baseline demographic, clinical, serological, and high-resolution CT findings were collected. NFC was semi-quantitatively scored with six domains ranging from 0 to 18. In addition, the overall patterns (sclerodermaon-scleroderma patterns) were determined.
Results:A total of 81 patients (31 with CTD-ILD, 18 with IPAF, and 32 with IIP) were included. The non-specific interstitial pneumonia pattern was the most common ILD pattern in the CTD-ILD and IPAF groups, whereas the usual interstitial pneumonia pattern was the most common in the IIP group. The semi-quantitative score of the CTD-ILD group was higher than that of the IPAF or IIP groups (5.8 vs 4.2 vs 3.0, p < 0.001, respectively). Giant capillaries and haemorrhages were more frequently present in the CTD-ILD and IPAF groups than in the IIP group. A scleroderma pattern was present in 27.8% of the IPAF group, whereas none of the IIP patients showed a scleroderma pattern.
Conclusions:NFC findings may be useful in classifying patients with ILD into CTD-ILD/IPAF/IIP.
