1.Auto-urotherapy in urticaria: progress report.
Acta Medica Philippina 0000;():0-
A group of 112 patients suffering from urticaria of varied etiology was treated with auto-urotherapy. The technic and preparation of the urine for injection is describedOf this group, 106 patients had a follow-up ranging from three months to three and a half years. There was no recurrence of the urticaria during this period of observation. One case failed to respond to this form of treatment (45 injections)There were no untoward reactions to the treatment save local pain on the site of injection, and abscess formation, observed in 4 cases. (Summary)
Urine
2.Correlative studies on the occurrence of urinary anisotropic lipid bodies in conditions associated with Proteinuria.
CELESTINO L ; LEE M ; RODRIGUEZ V ; DIZON A ; DAYSOG A JR
Journal of the Philippine Medical Association 0000;():0-
The incidence of anisotropic lipid material in the urine increases significantly with the degree of proteinuria. Lipid crystals were seen in all cases of nephrotic syndrome studied and in 11 of 28 non-nephrotic subjects with abnormal amounts of protein excretion per day. In 10 subjects without or with normal amounts of protein excretion per day, anisotropic lipid particles were not seenWhen the clinical diagnosis of all the subjects studied were divided into 2 groups as to whether they are known or not known causes of nephrotic syndrome, it was found that anisotropic lipid bodies were seen significantly more often in the former group. This observation among the non-nephrotic subjects inevitably leads to the question whether they can be regarded as pre-nephroticsThere was no correlation seen with serum albumin, non-protein nitrogen and total cholesterol with the excretion of urinary anisotropic lipid material. The lack of correlation with plasma levels of total cholesterol was surprising in view of the fact that Maltese crosses are composed of cholesterol ester and free cholesterol. This finding strengthens the observation that a renal factor possibly the presence of glomerular damage is a requirement for the occurrence of cholesteroluria. (Summary)
Urine, Lipids
3.Evaluation of Random Urine Sodium and Potassium Compensated by Creatinine as Possible Alternative Markers for 24 Hours Urinary Sodium and Potassium Excretion.
Hyunmin KOO ; Sang Guk LEE ; Jeong Ho KIM
Annals of Laboratory Medicine 2015;35(2):238-241
Sodium and potassium intake was assessed on the basis of its respective excretion levels in 24 hr urine samples. However, owing to the inconvenience of collection, we evaluated random spot urine for alternative sodium and potassium excretion markers. We included 250 patients who submitted 24 hr- and spot urine for clinical tests. However, 22 patients who showed 24 hr urine creatinine excretion levels <500 mg/day were excluded, because these samples possibly resulted from incomplete urine collection. Moreover, 24 patients were excluded because of their use of diuretics during the urine collection period. We observed significant correlations between 24 hr urine sodium excretion and both the sodium/creatinine (r=0.34, P<0.0001) and the sodium/specific gravity unit (SGU) ratios (r=0.19, P=0.007) in random urine samples. Similarly, 24 hr urine potassium excretion and both the spot urine potassium/creatinine (r=0.47, P<0.0001) and potassium/SGU ratios (r=0.28, P<0.0001) were significantly correlated. Although the estimated sodium/creatinine and potassium/creatinine ratios showed a significant correlation with 24 hr urine sodium and potassium excretion, respectively, further studies are required to develop a spot urine test for individualized monitoring of sodium and potassium excretion.
Biomarkers/urine
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Creatinine/*urine
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Humans
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Hypertension/pathology/urine
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Potassium/*urine
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Sodium/*urine
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Urinalysis
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Urine Specimen Collection
5.Research advances in detection techniques for urinary metabolites of phthalic acid ester.
Xiaoning ZHU ; Guoquan WANG ; Chunhua WU ; Yu'e JIN ; Dasheng LU ; Zhijun ZHOU
Chinese Journal of Industrial Hygiene and Occupational Diseases 2014;32(6):464-468
Esters
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urine
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Humans
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Phthalic Acids
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urine
6.Determination of cotinine, phenylglyoxylic acid and mandelic acid in human urine by GC/MS.
Yuan-Yang WU ; Wei-Xing SHI ; Shu-Qing CHEN
Journal of Zhejiang University. Medical sciences 2009;38(3):229-234
OBJECTIVETo establish a GC/MS method for analysis of cotinine (COT), phenylglyoxylic acid (PA) and mandelic acid (MA) in human urine.
METHODSHuman urine samples were extracted by CCl(3) and derivatized with MSTFA after dried completely. The contents of COT, PA and MA were measured by GC/MS method with DB-5MS capillary column and EI ion-source.
RESULTThe calibration curves for COT in urine samples were linear over the concentration ranges of 0.0002 approximately 3.5 microg ml(-1), while PA and MA were both of 1.25 approximately 160 microg ml(-1). The limits of quantification were 0.0002 microg ml(-1), 1.25 microg ml(-1) and 1.25 microg ml(-1) for COT, PA and MA, respectively. The assay recoveries for COT, PA and MA ranged from 89.53% approximately 102.4%, 84.88% approximately 91.46% and 83.46% approximately 13.6%, respectively.
CONCLUSIONThe established method can detect cotinine, phenylglyoxylic acid and mandelic acid simultaneously, which would be used in routine assessment and monitoring of the internal exposure to nicotine and styrene in human body.
Cotinine ; urine ; Environmental Pollutants ; urine ; Gas Chromatography-Mass Spectrometry ; Glyoxylates ; urine ; Humans ; Mandelic Acids ; urine
8.Investigation on elimination of two optic isomers of chlorpheniramine in urine on experiments in man
Pharmaceutical Journal 2004;44(2):42-43
The elimination of chlorpheniramine (CPAM) racemic isomers from human urine in experiment. The pharmacokinetic elimination of chlorpheniramine in the product contac including racemic chlorphenyramine and phenylpropano …was assessed in 9 health men and 9 women administrating 8mg racemic chlorphenyramine in Contac after an overnight fast. Urine samples were collected up to 144 hours and individual enatiomers of chlorpheniramine was defermined by HPLC method. There was no difference in the elimination of unchanged CPAM in urine from male and female subjects
Chlorpheniramine
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Urine
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Methods
9.Studies on extraction and in vitro anti-urolithic effect of the prescription ngu linh gia vi
Journal of Medicinal Materials - Hanoi 2003;8(2):76-81
Dried powder extraction: Among the components of the traditional oriental prescription “Ngu linh gia vi”, rhizoma Atractylodis macrocephalae, Polia, Polyporus, rhizoma Alismatis and cortex Cinnamomi were extracted with ethanol 80%; the others were extracted with boiled water. All the extracts were mixed with rhizoma Dioscoreae persimilis powder, then dried in vacuum. The total yield of the dried extract was 7.7% compared with the plant materials. Anti-urolithic effect: In vitro studies showed that the percentages of worn stones were respectively 0.92% (control group), 18.94% (low dose of dried extract group), and 19.97% (high dose of dried extract group).
Drugs
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Urine
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Medicine, Traditional
10.Reporting one case of abnormally high urine hCG level in the pregnancy
Journal of Vietnamese Medicine 2005;309(4):34-36
Reporting one case of abnormal high urine hCG level in the pregnancy. The abnormal high level was still in allowed limits, even higher than normal level. The maximum hCG level was observed at 11 weeks and 5 days of gestational age following the first days of the last menstrual periods. The symptoms such as nausea, vomiting would be severe with very low hCG, last until hCG achieved maximum. This patient was successfully managed with aminazin
Chorionic Gonadotropin
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Pregnancy
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Urine