No abstract available.
Rabies*

80% subjects among 50 bitten by dogs/cats were fully injected 4-6 doses of rabies vaccine. By ELISA (platelia Rage kit of Diagnostic Pasteur), we found that 42.5% of serum samples taken after injection 4 doses of rabies vaccine have titer 0.5IU/ml, it met WHO's minimum requirement. The GMT was 2.71 EU/ml. 62.5% of serum samples taken after injection 6 doses of rabies vaccine have titer 0.5IU/ml. The GMT was 3.14UE/ml.
Vaccines ; Rabies

This is a study on establishing the National References for inactivated rabies vaccine for human produced in ViÖt Nam. The results showed that the ViÖt Nam National References for Rabies Vaccine met the requirements of WHO
Vaccines ; Rabies

Rabies virus

Rabies virus ; physiology

The mortality rate due to rabies/100.000 inhabitants in Viet Nam was 0,43 during 1991-1995, was the highest mortality among 10 epidemic infectious diseases. From 1996-2000, some active interventive solutions had been implemented such as establishing the steering committee for rabies control; strengthening the role of the authority and co-ordination of ministries and sectors, promoting propaganda, education, training and building the special network; enhancing the quality of treatment and prevention for people who had been beaten by mad animals and suspected mad animals. As a result during 1996-2000 the mortality caused by bites of mad animals throughout the country reduced by more than 65% compared with 1991-1995. In some key provinces the mortality cause by bites of mad animals decreased 80-95%
Rabies ; Prevention & control

Study on the use of caprylic acid in the purification of anti rabies serum. The use of coprylic acid (octanoic) in the cleaning process IgG from horse plasma was studied to apply in the purification of anti rabies serum in the Institute of Vaccine and Biological Substances. When using caprylic acid in the purification of serum, the quality and quantity of the products were improved. The purity and colour of product was managed as desire. The process had a high effectiveness and short time of purification
Caprylic acid ; Rabies

1,763,616 victims were bitten by mad suspected dogs in Southern provinces during 5 years had been vaccineated, in which 148 victims died (0.08%). Ben Tre province had the highest victims and the highest mortality rate, while Ca Mau province was at the lowest. Especially there was no death by rabies in Binh Duong and Soc Trang provinces. There was an insignificant difference between male and female victims. The age over 15 was 61%; 91.47% had vaccineated before 15 days of bites and 80.71% bitten by dogs; 78% were mild bites, far from nervous centre. The victims died due to rabies decreased 50% in 2000 compared with this in 1996
Rabies ; Prevention & control

21,933 people were bitten by mad suspected cattles had been vaccinated and 171 patients died due to rabies during 1990-1997 in Hai Phong city. The mortality rate due to no vaccination was 76%, inadequate vaccination 12,9%. There wasn't death following the results of 100 cases who had been selected for study to evaluate the effect of Fuenzalida vaccine
vaccines ; Rabies ; death

Vnukovo-32 a cell culture rabies is used to study the vaccine strain technology of inactivated culture rabies vaccine production in primary hamster kidney cells. The master and working seeds meet the criteria of rabies vaccine strain titer (5.5 log LD 50 - 7.1 log LD 50/ml) according to WHO standard. During the study, we have used the procedure for inactivated, non concentrated rabies vaccine production of Russia and other countries procedures as references. The result was we constructed the procedure for inactivated, concentrated cell culture rabies vaccine production at laboratory scale.
Rabies Vaccines ; Cells, Laboratories