1.Pathophysiology of Proteinuria.
Korean Journal of Pediatrics 2004;47(Suppl 4):S877-S885
No abstract available.
Proteinuria*
2.Proteinuria.
Korean Journal of Pediatrics 2004;47(Suppl 4):S861-S866
No abstract available.
Proteinuria*
3.Proteinuria.
Seung Hyun YOO ; Byung Hoe KIM ; Eui Won HWANG
Korean Journal of Medicine 2002;62(4):369-378
No abstract available.
Proteinuria*
4.Albumin Creatinine Ratio as Screening Test for Microalbuminuria in Patients with Type 2 Diabetes.
Jung Eun LEE ; Jung Hwan PARK ; Dong Jun PARK ; Eun Young SEONG ; Kwon Wook JOO ; Yon Su KIM ; Curie AHN ; Jin Suk HAN ; Suhnggwon KIM ; Jung Sang LEE
Korean Journal of Nephrology 2004;23(3):405-411
OBJECTIVE: Albumin creatinine ratio (ACR) in a spot urine is replacing albumin excretion rate (AER) in 24 hour-collected urine as screening test for microalbuminuria because of simplicity and reliance. There are some controversies about the most relevant ACR value in detecting microalbuminuria. Most commonly recommended cut-off value is 30 mg/gm. Some recommends sex-specific ACR cut-off value: 17 mg/gm for men, 25 mg/gm for women. In this report, we evaluated diagnostic characteristics of ACR according to above different cut-off values and estimated most relevant ACR cut-off value for microalbuminuria in patients with type 2 diabetes. METHODS: Urine was collected for 24hours for the measurement of microalbumin in type 2 diabetes who admitted in SNUH. The next day, first morning urine was obtained for microalbumin and creatinine concentration in patients with albumin excretion rate (AER) below 300 mg/day. RESULTS: 33% of total 156 patients had microalbuminuria. ACR correlated positively with AER. According to regression equations of AER and ACR, an AER of 30 mg/day corresponded to an ACR of 32 mg/gm. Positive and negative predictive values of ACR 30 mg/gm for microalbuminuria were 81% and 84% in men. In women, these were 80% and 86% respectively. Using recommended sex-specific ACR cutoff values, these were 52% and 94% in men, 68% and 91% in women. The most relevant ACR cutoff from receiver operating characteristics curve was 32 mg/gm in our study. CONCLUSION: Using ACR 30 mg/gm as cut-off values of microalbuminuria, positive and negative predictive value were above 80% in both men and women. In patients visiting SNUH, ACR 32 mg/gm may be more relevant in screening microalbuminuria in type 2 diabetes.
Albuminuria
;
Creatinine*
;
Female
;
Humans
;
Male
;
Mass Screening*
;
Proteinuria
;
ROC Curve
5.Performance Evaluation of MEDITAPE UC-11A Strip Test in Estimating the Urine Albumin-to-Creatinine Ratio and Urine Protein-to-Creatinine Ratio
Shinae YU ; Sae Am SONG ; Kyung Ran JUN ; Jeong Nyeo LEE
Laboratory Medicine Online 2020;10(1):52-57
Proteinuria, including albuminuria, is a primary or major clinical sign of kidney disease. The urine albumin-to-creatinine ratio (UACR) and urine protein-to-creatinine ratio (UPCR) are used to screen patients with chronic diseases, such as diabetes and hypertension, which increase the risk of chronic kidney disease. Here, we evaluated the performance of the MEDITAPE UC-11A strips (Sysmex, Japan), compared with that of the quantitative assay, in assessing UACR and UPCR.METHODS: We obtained a total of 808 random urine specimens. UACR and UPCR, semiquantitatively analyzed using MEDITAPE UC-11A strips with a UC-3500 automated strip reader (Sysmex, Japan), were compared to UACR and UPCR measured by a quantitative assay.RESULTS: The concordance rates of UACR and UPCR, analyzed using MEDITAPE UC-11A, and those analyzed using the quantitative assay, were 70.1% and 78.7%, respectively. Using UACR, analyzed via quantitative assay, as a reference to estimate albuminuria (UACR >30 mg/g), the concordance rate, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of UACR, analyzed using MEDITAPE UC-11A, were 80.5, 97.5, 67.0, 70.3, and 97.1%, respectively. Using UPCR, analyzed via quantitative assay, as a reference to estimate proteinuria (UPCR >0.15 g/g), the concordance rate, sensitivity, specificity, PPV, and NPV of UPCR, analyzed using MEDITAPE UC-11A, were 86.7, 94.4, 81.5, 77.6, and 95.6%, respectively.CONCLUSIONS: UACR and UPCR, analyzed using MEDITAPE UC-11A, exhibited relatively high sensitivity and NPV, which is beneficial for laboratory screening for both albuminuria and proteinuria.]]>
Albuminuria
;
Chronic Disease
;
Humans
;
Hypertension
;
Kidney Diseases
;
Mass Screening
;
Proteinuria
;
Renal Insufficiency, Chronic
;
Sensitivity and Specificity
6.A Case of Nutcracker Syndrome Presenting with Orthostatic Proteinuria.
Young Bin KIM ; Sung Chul BAEK ; Hwang Jae YOO ; Cheol Hong KIM ; Hyun Hee LEE ; Pyung Kil KIM ; Noh Hyuck PARK
Journal of the Korean Society of Pediatric Nephrology 2004;8(1):74-79
Orthostatic proteinuria is documented as a benign condition and the most common cause of isolated proteinuria. The etiology and pathogenesis of orthostatic proteinuria is not clear yet. Recently there were a few report that nutcracker syndrome seemed to cause orthostatic proteinuria. We experienced a case of a twelve-year-old female patient with incidently discovered orthostatic proteinuria who was suspected to have nutcracker phenomenon by doppler sonography. We confirmed this patient as nutcracker syndrome by renal venography.
Female
;
Humans
;
Phlebography
;
Proteinuria*
7.Correlation between Microalbuminuria Checked by RIA & Micral-Test®.
Chan Woo LEE ; Kyu Chang WON ; Soo Bong CHOI
Yeungnam University Journal of Medicine 1991;8(2):158-163
It is evident that an elevation of airway albumin excreation rate without clinical proteinuria strongly predicts a later progression on diabetic renal disease. So we studied the correlation between Microalbumin checkly RIA & Micral-Test®. We collected urine between 08:00 h and 08:00 h next day and then checked microalbuminuria by radioimmunoassay method and Micral-Test® The results are as follows: 1. There was significant correlation between microalbuminuria checked by RIA & Micral-Test® 2. There was poor correlation between diabetes duration or HV-A1c and maximal change in albumin excreation rate. 3. So we concluded that Micral-Test® can be used in laboratory instead of RIA.
Methods
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Proteinuria
;
Radioimmunoassay
8.Detection of tubular proteinuria using gradient gel SDS-PAGE.
Korean Journal of Clinical Pathology 1991;11(3):529-536
No abstract available.
Electrophoresis, Polyacrylamide Gel*
;
Proteinuria*
9.Differential Diagnosis and Treatment of Proteinuria.
Korean Journal of Medicine 2013;85(4):374-377
No abstract available.
Diagnosis, Differential
;
Proteinuria
10.Differential Diagnosis and Treatment of Proteinuria.
Korean Journal of Medicine 2013;85(4):374-377
No abstract available.
Diagnosis, Differential
;
Proteinuria