No abstract available.
Lymphocytosis* ; T-Lymphocytes* ; Thymoma*

No abstract available.
Cerebrospinal Fluid* ; Child* ; Humans ; Lymphocytosis* ; Meningitis, Bacterial*

A case of infectious mononucleosis was presented. She was admitted to the hospital with the anterior cervical lymphadenopathy. Erythematous skin rashes on both low extermities, and splenomegaly. Her chief complaints were fever and sore throat. She showed atypical lymphocytes in peripheral blood smear with relative lymphocytosis. Mono-spot test was positive. She received symptomatic therapy and discharged without any complications. So, we report this case and review the brief literatures of infectious mononucleosis with the respect to etiology, clinical course, and histological characteristics of the disease.
Exanthema ; Fever ; Infectious Mononucleosis ; Lymphatic Diseases ; Lymphocytes ; Lymphocytosis ; Pharyngitis ; Splenomegaly

Self-healing reticulohistiocytosis is a perinatal disease characterized by rapidly developing and involuting benign histiocytic infiltration of the skin and other organ. We had recently experienced a case of a self-healing reticulohistiocytosis in 99-day-old infant who presented with multiple erythematous nodular lesions on face and trunk and pancytopenia. Our case differed from those previously reported in that extracutaneous involvement was found. The patient had pancytopenia, hypertriglyceridemia, hypofibrinogenemia hyperferritinemia and hepatosplenomegaly as well as skin lesions. Bone marrow showed a marked lymphocytosis with many histiocytes. We described a detailed clinical features of this case and reviewed the literatures.
Bone Marrow ; Histiocytes ; Humans ; Hypertriglyceridemia ; Infant ; Lymphocytosis ; Pancytopenia ; Skin

T-cell prolymphocytic leukemia (T-PLL) is a post-thymic T-cell malignancy that has an aggressive clinical course and it is a distinct clinico-biological entity from other T-cell disorders. It is now apparent that this disease represents a separate entity from CLL. Clinically, T-PLL presents with hepatosplenomegaly, lymphadenopathy, skin lesion, and marked lymphocytosis exceeding 100x109/L. Because its clinical course is aggressive, the treatment is difficult. We report a case of small cell variant of T-cell with a review of literatures.
Leukemia, Prolymphocytic, T-Cell* ; Lymphatic Diseases ; Lymphocytosis ; Skin ; T-Lymphocytes*

Humans ; Infectious Mononucleosis/complications* ; Lymphocytosis ; Lymphohistiocytosis, Hemophagocytic/etiology*

B-Lymphocytes ; Bone Neoplasms ; Humans ; Lumbar Vertebrae ; Lymphocytosis ; Plasmacytoma

Sulfone hypersensitivity syndrome, which is characterized by fever, skin rash, hemolytic anemia, atypical lymphocytosis, and acute hepatic injury, is a potentially fatal variant of dapsone hypersensitivity. A 62-year-old woman with a history of arthralgia developed sulfone syndrome while receiving dapsone 100 mg/day for 20 days. Fever, malaise, prominent rashes, hepatitis, eosinophilia and hemolytic anemia developed and she which required hospitalization. The patient's symptoms reversed following discontinuation of dapsone and administration of steroid (0.5 mg/kg). A case of sulfone syndrome and a brief review of the literature were presented.
Anemia, Hemolytic ; Arthralgia ; Dapsone* ; Eosinophilia ; Exanthema ; Female ; Fever ; Hepatitis ; Hospitalization ; Humans ; Hypersensitivity* ; Lymphocytosis ; Middle Aged

Diffuse infiltrative lymphocytosis syndrome is an autoimmune syndrome that is characterized by the oligoclonal expansion of CD8+ T-lymphocytes in response to human immunodeficiency virus (HIV) antigens. The clinical manifestations include bilateral enlargement of the parotid glands, lymphocytic interstitial pneumonitis, lymphocytic hepatitis, neurological involvement and systemic lymphadenopathies. In addition to a positive HIV test, the diagnostic histopathological findings are CD8+ T-lymphocytic infiltrations in the lymphnodes, liver, lung, muscle and the salivary or lacrimal glands without granulomatous or neoplastic involvement. We report a case of pulmonary involvement of diffuse infiltrative lymphocytosis syndrome that was associated with a human immunodeficiency virus infection.
Hepatitis ; HIV* ; Humans* ; Lacrimal Apparatus ; Liver ; Lung ; Lung Diseases, Interstitial ; Lymphocytosis* ; Parotid Gland ; T-Lymphocytes

There have been some 50 reports on the blood pictures of leprosy patients, but all of them have been dealt with the peripheral blood and more over each investigator presented the different data. In order to find cut the typical blood pictures both peripheral and bone marrow as well as the blood pictures between the various types of leprosy and the nature of anemia brought about after the use of D.D.S. derivatives, the author examined the blood of 53 cases of early leprosy patients with the following results: 1. Peripheral Blood Pictures: a. About one third of leprosy patients showel the anemic blood picture and one half of T type leprosy cases gave the anemic picture. Almost all of them were normocytic and hypochromic anemia. b. Shift to the left was found in about 50% of the cases. c. Eosinophilia was observed in the majority of the cases and all of the T type showed eosinophilia. d. There was found lymphocytosis in approximately one third of total cases and half of T type patients showed lymphocytosis. e. Lymphopenia was encountered in one fourth of them and was most frequently seen in L type patients. F. About half of all cases showed monocytopenia. g. Only 10% of patients showed the accelaration in Erythrocyte Sedimentation Rate. 2. Bone Marrow Findings: a. Myeloblastosis was noted in about 50% of them and more frequently seen in T type and I group than the other types. b. There was observed eosinophilia in almost all cases and especially its frequency was higher in T type and I group. c. Lymphocytosis was found in about one third of the total eases and its frequency was highest in L type. whereas in the peripheral blood the lymphocytosis was most frequently seen in T type. d. Plasmocytosis was noted in the majority of the patients and was found in all cases of T type and I group. 3. Seventy percent of the cases showed the increased WBC alkaline phosphatase. 4. No granulomatous changes or any other pathological changes were noted in the histological section of the bone marrow
Alkaline Phosphatase ; Anemia ; Anemia, Hypochromic ; Blood Sedimentation ; Bone Marrow ; Eosinophilia ; Humans ; Leprosy* ; Lymphocytosis ; Lymphopenia ; Research Personnel