1.A case of antineoplastic treatment - related leukoencephalopathy.
Jee Suk YU ; Se Hee HWANG ; Baeck Hee LEE ; Yong Seung HWANG ; Hyo Seop AHN
Journal of the Korean Child Neurology Society 1993;1(1):165-172
No abstract available.
Leukoencephalopathies*
2.Chemotherapy-induced leukoencephalopathy: A case series.
Paula Bianca E. NUQUI ; Flerida G. HERNANDEZ
Journal of Medicine University of Santo Tomas 2021;5(1):658-663
Rationale: Leukoencephalopathy, a complication associated with chemotherapy has been reported after giving high doses of methotrexate and cytarabine with no specific risk factors to date.
Objectives:
1. To review the prevalence of chemotherapy-induced leukoencephalopathy in children with acute lymphoblastic leukemia (ALL).
2. To present the clinical course, pathogenesis and neuro-imaging findings of chemotherapy-induced leukoencephalopathy in children with ALL.
Case: We reported three cases of adolescent ALL precursor B-cell patients who received high doses of methotrexate and presented with neurologic and MRI findings consistent with leukoencephalopathy. Our patients were only placed on supportive measures with adequate hydration, without providing any special intervention. Yet, all of them had complete neurological recovery.
Discussion and Summary: Methotrexate is a cell cycle-specific agent that inhibits the enzyme dihydrofolate reductase, preventing the conversion of folic acid to tetrahydrofolic acid and inhibiting cell replication. It is one of the most commonly implicated drug causing leukoencephalopathy. [3] On MRI T2-weighted images, all of them had hyperintensities on the posterior frontal/parietal corona radiata and centrum semiovale consistent with leukoencephalopathy. Complete recovery happened spontaneously in all of the cases. There is no standard treatment for acute and subacute toxicities from methotrexate.
Leukoencephalopathies ;
3.Toxic Leukoencephalopathy and Hypokalemia Due to Exposure to Trimethyltin.
Zigao WANG ; Lu XIONG ; Hengbing ZU
Journal of Clinical Neurology 2017;13(3):298-299
No abstract available.
Hypokalemia*
;
Leukoencephalopathies*
4.Reversible Delayed Hypoxic Leukoencephalopathy from Respiration Failure during Sleep
Subin LEE ; Seung Ho RYU ; Byoung Seok KIM ; Jeongkyu LEE ; Hyun Jeong HAN
Journal of the Korean Neurological Association 2018;36(4):375-377
No abstract available.
Leukoencephalopathies
;
Respiration
5.A Case of Post-Transfusion Posterior Leukoencephalopathy with Cytotoxic and Vasogenic Edema.
Jong Yun LEE ; Sun Ah PARK ; Seung Koo LEE ; Kyoung HEO ; Byung In LEE
Journal of the Korean Neurological Association 2003;21(1):97-100
We report a patient who developed posterior leukoencephalopatty (PLE) after a transfusion with vasospasm and both features of cytotoxic and vasogenic edema. The cytotoxic edema developed in the cerebral region hemodynamically more compromised. Different mechanisms may occur in PLE according to the degree of ischemic burden related to vasospasm.
Edema*
;
Humans
;
Leukoencephalopathies*
6.Whole Brain Radiation Therapy Associated Diffuse Progressive Leukoencephalopathy and Brain Atrophy.
Byeong suk KIM ; Jin Hee KIM ; Yun Ha HWANG ; Taewon KIM
Journal of the Korean Neurological Association 2017;35(3):189-190
No abstract available.
Atrophy*
;
Brain*
;
Leukoencephalopathies*
7.Methotrexate-Induced Leukoencephalopathy Presenting Like Acute Stroke
Woo Seok HA ; Bo Kyu CHOI ; Yujin KOO ; Hyo Suk NAM
Journal of the Korean Neurological Association 2019;37(4):417-419
No abstract available.
Leukoencephalopathies
;
Methotrexate
;
Stroke
8.Radiation-induced Leukoencephalopathy Presenting as Lower Body Parkinsonism.
Jaehyung KIM ; Chang Hwan RYU ; Wonjae SUNG ; Hyunseung GWAK ; Kyung Pil OH ; Seong Ho KOH ; Kyu Yong LEE ; Young Joo LEE ; Hojin CHOI
Journal of the Korean Neurological Association 2015;33(4):355-357
No abstract available.
Cranial Irradiation
;
Leukoencephalopathies*
;
Parkinsonian Disorders*
9.Alanyl-tRNA Synthetase 2-Related Dementia with Selective Bilateral Frontal Cystic Leukoencephalopathy.
Guilhem CARLE ; Alexandre MORIN ; Camille NOIRAY ; Perrine ROY-JOLY ; Laurent COHEN ; Richard LEVY ; Simon SAMAAN ; Yann NADJAR
Journal of Clinical Neurology 2018;14(3):420-422
No abstract available.
Alanine-tRNA Ligase*
;
Dementia*
;
Leukoencephalopathies*
10.Poliodystrophia Cerebri Progressiva(Diffuse Degeneration of Grey Matter).
Yonsei Medical Journal 1960;1(1):45-51
No abstract available.
Diffuse Cerebral Sclerosis of Schilder*
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