1.Complementary and Alternative Medicine(CAM) in Urology.
Korean Journal of Urology 2008;49(3):193-202
An increasing use of complementary and alternative medicine(CAM) is apparent both in Asian and in Western countries for the management of numerous diseases to improve symptoms and to improve general health and well being. Many patients with benign prostatitc hyperplasia(BPH) and lower urinary tract symptoms(LUTS), erectile dysfunction(ED), urinary tract infection(UTI) are using CAM. Complementary and alternative medicines for urologic malignancies such as renal cell carcinoma, bladder cancer, and prostate cancer are also one of the important issues in the management of patients. Dietary supplements and nutraceuticals are commonly used modality for the patients with BPH/LUTS or ED. Vegetables and cruciferous fruits showed significant preventive effect on urologic malignancies in many studies. Phytotherapy for BPH including beta-sitosterols, saw palmetto, pygeum, and nettles etc, is under vigorous research for their therapeutic effect. No solid evidence showing better effective treatment modality for ED than placebo was found yet in CAM area. Recently, a potent NO donor, L-arginine is under research with promising results. Cranberry juice has been used for the patients with recurrent UTI but safety was a limit for its use. Various antioxidants have been studied for prevention of urological malignancies. Lycopene, isoflavone, vitamin A, C, and E, and polyphenols showed the possibility of decreasing cancer incidence in many studies but their effect is still controversial. Vitamin D is known to be associated with cancer progression and the effect of combination treatment with other chemotherapeutic agents for advanced cancer is under trial. CAM is used by a number of patients with urological diseases and urologists need to have both accurate knowledge and apprehension of CAM. The possible effects and side effects should be defined and offered to the urologic patients by urologists.
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2.Two Cases of Congenital Renal Hypoplasia.
Jun Ho CHANG ; Oh Tac WHANG ; Tae Eun CHOUNG ; Kwang Soo JUN ; Eung Jib KWAN
Korean Journal of Urology 1971;12(4):409-412
The incidence of congenital unilateral renal hypoplasia is extremely rare.Two cases of congenital unilateral renal hypoplasia were presented with review of literature.
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3.MR Findings of the Intraventricular Tumors.
Ji Hoon SIN ; Ho Kyu LEE ; Hyun Jin KIM ; Chang Jin KIM ; Soo Mee LIM ; Myung Joon LEE ; Choong Gon CHOI ; Dae Chul SUH
Journal of the Korean Radiological Society 1998;38(6):993-999
With regard to various pathologic conditions, it is important to understand not only MR findings, which dependon the anatomic location of intraventricular lesions, but also the anatomic location most appropriate for surgicalintervention. In this paper we will analyze and demonstrate the incidence and characteristic MR findings ofvarious intraventricular tumors according to the location of ventricles.
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4.Study on the Anti-Smooth Muscle Antibody and Anti-Nuclear Antibody of Chronic Active Hepatitis, Chronic Persistant Heratitis and Liver Cirrhosis in Korea.
Kap No LEE ; Seung Yong PAIK ; Sang Kook LEE
Korean Journal of Pathology 1986;20(2):147-156
In Korea chronic liver diseases are the important medical issues because of their high incidence, poor prognosis and no available therapeutic resume. It is believed that the etiologic agent of most of chronic liver diseases in Korea is hepatitis B virus. To find out the incidence of positivity and to understand the autoantibodies in some of the chronic liver diseases in Korea, anti-smooth muscle antibody and anti-nuclear antibody tests were performed on 43 patient serum with chronic active hepatitis, 13 patient serum with chronic persistant hepatitis and 20 patient serum with liver cirrhosis, who diagnosed by liver biopsies. The results of the study are summarized as follows: 1) The positivity of anti-smooth muscle antibody in chronic active hepatitis was 93.0%, that in chronic persistant hepatitis 60.0% and that in liver cirrhosis 80.0%. 2) The positivity of anti-nuclear antibody in chronic active hepatitis was 18.6%, that in chronic persistant hepatitis 15.4%, that in liver cirrhosis 5.0%. 3) The test efficiency of anti-smooth muscle antibody to differentiate chronic active hepatitis from chronic persistant hepatitis and liver cirrhosis was 48.7%. The above results suggest that the antismooth muscle antibody may be related to the "necrosis of liver cells", and further studies are needed to fine out any relationship between the autoantibody and the disturbance of immune regulatory function if there is, as this study suggested.
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5.Flexion-distraction Injury in Cervico-thoracic Junction: A Case Report.
Ye Soo PARK ; Kang Wook KIM ; Ki Chul PARK
Journal of Korean Society of Spine Surgery 2006;13(3):215-218
Injuries at the cervico-thoracic junction can be difficult to diagnose (with an incidence as high as 9% of all spinal injuries) and to stabilize, because of anatomic complexities. We report a case with that was treated with a lateral mass screw and transpedicular screw-rod fixation for a flexion-distraction injury at the cervico-thoracic junction and we present a review of the literature.
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6.Incidence of Parasites in Seoul Area Based on An Examination of the Severance Hospital Out-Patients.
Chin Thack SOH ; Keun Tae LEE ; Eui Woong SHIN ; Tae Chul KANG
Yonsei Medical Journal 1961;2(1):31-41
Of 14,682 samples of feces examined, 81.7% were positive for intestinal helminths. Trichocephalus trichiurus was observed most frequently, in 73.2%. Eight other species of helminths found were Ascaris lumbricoides, Hookworm, Trichostrongylus orientalis, Clonorchis sinensis, Tapeworm, Hymenolepis nana, Paragoniumus westermani and Enterobius vermicularis, listed in decreasing order. Double infections were found more frequently than single infections, and mixed infection of five or more species of helminths occurred in 0.2% Of 10,320 samples of feces examined, 22.3% were positive for intestinal protozoa, Entamoeba coli was observed most frequently, in 11.1%. Six other species, Endolimax nana, Giardia lamblia, Entamoeba histolytica, Iodamoeba butschlii, Chilomastix mesnill and lsospora hominis were found, in the order. It was noticed that E. histolytica was found more frequently in trichurial infection than with other helminths. Of 1,050 samples of sputum from the T. B. Clinic, 7.0% were positive for paragonimus eggs. Trichomonas vaginalis were found in 35.8%of 1,146 vaginal swabs examined. Seven cases of Plasmodium vivax infection were found among 140 suspected blood smears.
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7.A Clinical Study on Herpes Zoster and Chicken Pox.
Jin Woo KIM ; Si Yong KIM ; Kang Woo LEE ; Won HOUH ; Ock Ja CHO ; Seung Won LEE
Korean Journal of Dermatology 1982;20(1):69-76
The purpose of this study was to elucidate the epidemiology and the clinical characteristics of herpes zoster and chicken pox. 703 patients with herpes zoster and 237 patients with chicken pox who were seen at the Department of Dermatology, St. Marys Hospital during 8 years were taken for this retrospective study. Both groups of the patients were evaluated in regard to annual, seasonal and monthly incidence, age incidence and sex ratio. Patients with herpes zoster were further assessed concerning associated conditions, dermatomic distributions and complications. The results were as follows, 1. The annual rate for chicken pox ranged from 0.03% to 0.18% (mean 0.13%) and revealed no epidemics, however, its incidence was higher in early summer and winter. There was no sexual difference. Chicken pox was seen most. frequently in the 0-9 year age group (91.1%). 2. The annual rate for herpes zoster ranged from 0.23% to 0.52% (mean 0.38%). There were no significant annual, seasonal and monthly variations, and there was a. equal sex ratio. Herpes zoster was seen most frequently in the 50-59 year age group (19.1%) 3. The frequencies of the associated conditions in herpes zoster, in descending order, were infectious disease (2. 7%), diabetes mellitus (2.3%), malignant neoplasm(1. 4%), immunosuppressive drug (l. 4%), autoimmune disease (0.6%), and radiation therapy (0.4%). 4. The dermatomic involvement of herpes zoster was most frequent on thoracic dermatome (53.5%) and others were cervical (16.5%), lumber (10.1%), ophthalmic branch of trigeminal nerve (8.8%), sacral (1.6%), maxillary branch of trigemenal nerve (1.3%), mandibular branch of trigemical nerve (0.6%) and facial nerve dermatome (0.1%). The incidence of involving two different dermatomes was 2.9% and was most common on cervicothoracic dermatome (1.8%). However, one case of cervico thoracic dermatome showed bilateral involvement. 5. The most common complication of herpes zoster was postherpetic neuralgia (6.5%) and others were secondary bacterial infection (2.6%), keratoconjunctivitis (0.6%), keloid formation (0.3%), generalized varicelliform eruption (0.1%), Ramsay-Hunt syndrome (0.1%) and recurrent herpes zoster (0.1%). The mean age of incidence for postherpetic neuralgia was 58.4 years and its incidence was the highest over 70 years (39.5%). Postherpetic neuralgia was most frequently seen in the involvement of ophtalmic branch of trigeminal nerve.
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8.A Statistical Study of Dermatoses (1971 - 1980).
Kee Seok HUH ; Jong Bong KAHNG ; Inn Ki CHUN ; Young Pio KIM
Korean Journal of Dermatology 1982;20(1):59-67
The statistics of 40,611 new cases of skin diseases seen in Dermatologic department of Chonnam University Hospital from 1971 to 1980 are analysed and significant changes in incidence of the 25 most common dermatoses are discussed in detail and the results are comared with other surveys. The results of this study are summed up in 4 tables. Table 1. Shows the annual frequency of the 25 most common dermatoses. Table 2. Shows the frequency of the 25 most common dermatoses by age group. Table 3. Shows the frequency of the 25 most common derrnatoses by season, sex and region. Table 4. Shows the comparison of frequency of the 20 most common dermatoses with other reports.
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9.Study on Establishment of Disease Database and Query System Through Internet Using Uniform Hospital Discharge Data Sets.
Yoo Kyung PU ; Kwang Hwan KIM ; Sun Won SEO ; Jin Sook SUH ; Mi Jeong KIM ; Jung Don SEO ; Seok Jun YOON ; Young Sung LEE ; Moo Sik LEE
Journal of Korean Society of Medical Informatics 2002;8(3):19-26
It is necessary to have accurate statistical data of disease for planning and evaluating public health policy as well as assessing population health index. The national health insurance data is the only data to assess incidence of diseases nation-wide. However, inaccuracy of the data pose serious limitations of use of the data. The Medical Record Departments of individual health facilities have used discharge summary information for hospital management and clinical research, but a nation-wide integrated database of diseases has not been setup and utilized. We applied previously developed Korean Uniform Hospital Discharge Data Sets to collect discha rge summary data from health care facilities and establish integrated database. We also made the question and answer column about disease of the database in the internet. We collected patient discharge data from a tertiary-care hospital for one year using the electronic discharge summary data collection system, except for health care costs. The internet querying system provided optional selection of columns or rows, individual and/or disease groups and surgical procedures. To make query easy, the system provided various functions like querying codes of diseases and/or surgical operations, reviewing questions, downloading results via excel files, help functions of query. The establishment of disease database and the interactive system through internet is in its inception, further studies may be necessary to make it a user friendly and accurate system. There is a need of an accurate assessment of current population-based health status and future trends in Korea. It is hoped that this study may trigger to establish national accurate database for enhancing studies of health policy making, clinical research and vital health statistics by expanding data collections to the se condary- care and primary- care institutions.
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10.Spindle Cell Carcinoma in Larynx: A case showing bone formation.
Hye Kyung AHN ; Hye Rim PARK ; Young Euy PARK
Korean Journal of Pathology 1993;27(3):293-295
Spindle cell carcinoma of the upper aerodigestive tract mucosa was usually presented as polypoid mass and shows squamous cell carcinoma or dysplasia in the surface and underlying spindle cell proliferation. The spindle cell area discloses a variable pattern of sarcoma including rare osteosarcoma of 0~20% incidence. The histogenetic origin of the spindle cell component is now considered a metaplasia of squamous cell carcinoma. We experienced a case of spindle cell carcinoma of larynx showing massive underlying bone formation with proliferation of osteoclast-like cells in 75 year-old man. The immunohistochemical study demonstrates positive reaction with cytokeratin in area of squamous cells and with vimentin in area of spindle cells and osteoclasts. There are very focal reactivity for high molecular weight cytokeratin in spindle cell area.
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