No abstract available.
Hypokalemia

No abstract available.
Hypokalemia*

No abstract available.
Hypokalemia

No abstract available.
Hypokalemia* ; Leukoencephalopathies*

Thyrotoxic periodic paralysis represents a rare neurological emergency of an endocrine disorder. It poses a diagnostic challenge to the clinicians, as it is an uncommon disorder and its clinical presentation is similar to the more common hypokalemic paralysis. Adding to the diagnostic dilemma is that most patients do not have prior history of thyroid disorder and only have subtle features of hyperthyroidism. Hence, the diagnosis can be easily missed without a high clinical index of suspicion. These patients usually present to the emergency department with acute flaccid paralysis and all physicians should be aware of this clinical entity. The disease can be life-threatening if early diagnosis and prompt therapy is not initiated. We report three interesting cases in which periodic paralysis was the initial manifestation of underlying Graves’ disease in two and occurred in the third case who was previously diagnosed with thyrotoxicosis due to non-adherence to drug therapy.
Hypokalemia ; Paralysis

No abstract available.
Diarrhea* ; Hypokalemia* ; Vipoma

No abstract available.
Humans ; Hypertension* ; Hypokalemia*

No abstract available.
Alkalosis ; Humans ; Hypokalemia

Proton pump inhibitors (PPIs) are the mainstay of therapy for all gastric acid related diseases and are commonly used in current clinical practice. Although widely regarded as safe, PPIs have been associated with a variety of adverse effects, including hypomagnesaemia. The postulated mechanism of PPI-related hypomagnesaemia involves inhibition of intestinal magnesium absorption via transient receptor potential melastin (TRPM) 6 and 7 cation channels. PPI-induced hypomagnesaemia (PPIH) has become a well recognized phenomenon since it was first reported in 2006. Clinical concerns arise from growing number of case reports presenting PPIH as a consequence of long-term PPI use, with more than 30 cases published to date. In this article, we report 2 cases of PPIH associated with the use of pantoprazole. Both patients presented with severe hypomagnesaemia and hypocalcaemia. One of them had associated hypokalemia and cardiac arrhythmia. A casual relation with PPIs postulated and supported by resolution of electrolyte abnormalities after discontinuation of PPIs.
Proton Pump Inhibitors ; Hypokalemia

Background: Although decreased potassium levels may have a role in the etiopathogenesis of preeclampsia, small number of studies has been done to determine their relationship. Objectives: This study was done to know whether serum potassium is significantly decreased in hypertensive disorders of pregnancy, to determine if the level of potassium correlates with the severity of hypertension, to know whether we can recommend serum potassium as part of preeclamptic work up, and ultimately, to determine if potassium supplementation can be advised to preeclamptic women during prenatal check-up. In this prospective, cross sectional study, subjects were 338, 169 of whom had uncomplicated pregnancies, while 169 had preeclampsia (72 of whom had systolic BP(SBP) 140-150mmHg, while 97 had SBP ?160mmHg). Baseline serum potassium were taken upon admission. The mean serum potassium was significantly lower at 3.37±0.41mmol/L (p-value<0.0003) in hypertensive women (versus 3.62±0.31mmol/L in uncomplicated pregnancies). Furthermore, the serum potassium was significantly decreased in patients with SBP>160mmHg (3.31±0.46) when compared with those with SBP140-150mmHg (3.45±0.32), with p0.013. Wilcoxon Signed-Rank Test showed Z-value -5.68 (significant at p?0.05), showing a significant difference between the level of serum potassium in normotensive compared to hypertensive patients. Chi-Square test showed X2?45.46 (in the critical region 5.9), therefore the level of serum potassium is dependent on the level of BP. Pearson Correlation coefficient showed r -0.1135 stating a negative correlation, hence, as the BP increases, serum potassium decreases. Conclusion This study suggests that hypokalemia observed in preeclamptic patients may bring about altered homeostatis in serum and therefore may act as predisposing factors in pathogenesis of preeclampsia. The authors recommend the addition of serum potassium as part of the criteria of severity of preeclampsia. Hypertensive pregnant women are advised to consume diet containing adequate amount of potassium or have a potassium supplementation during prenatal check up.
Hypokalemia ; Pre-Eclampsia