1.The STAT3 in Glucose Homeostasis.
Bon Jeong KU ; Su Hyeon PARK ; Koon Soon KIM ; Young Kun LIM ; Min Ho SHONG
Journal of Korean Society of Endocrinology 2004;19(3):274-280
No abstract avaiable.
Glucose*
;
Homeostasis*
2.Function of Adipocytes in Energy Homeostasis.
Journal of Korean Society of Pediatric Endocrinology 2002;7(2):145-149
No abstract available.
Adipocytes*
;
Homeostasis*
3.FEA model analysis of the effects of the stress distribution of saddle-type implants on the alveolar bone and the structural/physical stability of implants.
Yoon Soo KONG ; Jun Woo PARK ; Dong Ju CHOI
Maxillofacial Plastic and Reconstructive Surgery 2016;38(2):9-
BACKGROUND: As dental implants receive masticatory stress, the distribution of stress is very important to peri-implant bone homeostasis and implant survival. In this report, we created a saddle-type implant and analyzed its stability and ability to distribute stress to the surrounding bone. METHODS: The implants were designed as a saddle-type implant (SI) that wrapped around the alveolar bone, and the sizes of the saddles were 2.5, 3.5, 4.5, and 5.5 mm. The X and Y displacement were compared to clarify the effects of the saddle structures. The control group consisted of dental implants without the saddle design (CI). Using finite element modeling (FEM), the stress distribution around the dental implants was analyzed. RESULTS: With saddle-type implants, saddles longer than 4.5 mm were more effective for stress distribution than CI. Regarding lateral displacement, a SI of 2.5 mm was effective for stress distribution compared to lateral displacement. ASI that was 5.6 mm in length was more effective for stress distribution than a CI that was 10 mm in length. CONCLUSIONS: The saddle-type implant could have a bone-gaining effect. Because it has stress-distributing effects, it might protect the newly formed bone under the implant.
Dental Implants
;
Homeostasis
4.Research progress on autophagy regulating excessive inflammation.
Acta Physiologica Sinica 2014;66(6):739-745
Autophagy is a highly conserved cellular self-digestion pathway, by which intracellular damaged proteins or organelles are delivered to lysosomes for degradation, so as to protect from various dangerous stimuli and maintain cellular homeostasis. Inflammation is a defensive response to injury or pathogens, through which various inflammatory mediators coordinate host defense and repair. However, uncontrolled inflammatory responses can lead to secondary damage and pathogenesis of inflammatory disease. Recent studies indicate that autophagy pathway and related proteins may play important roles in regulating immune response and controlling excessive inflammation. This review introduced research progress in the role of autophagy in regulating excessive inflammation and possible mechanisms.
Autophagy
;
Homeostasis
;
Humans
;
Inflammation
5.Sodium Homeostasis by Neonatal Kidney.
Journal of the Korean Pediatric Society 1987;30(1):17-25
No abstract available.
Homeostasis*
;
Kidney*
;
Sodium*
6.Regulation of Calcium and Phosphorus Homeostasis.
Journal of Korean Society of Pediatric Endocrinology 2001;6(1):1-2
No abstract available.
Calcium*
;
Homeostasis*
;
Phosphorus*
7.Molecular basis and homeostatic regulation of Zinc taste.
Rui LUO ; Yuxiang ZHANG ; Yinjun JIA ; Yan ZHANG ; Zongyang LI ; Jieqing ZHAO ; Ting LIU ; Wei ZHANG
Protein & Cell 2022;13(6):462-469
8.Morphological analysis of autophagy.
Acta Pharmaceutica Sinica 2016;51(1):39-44
Autophagy is an important homeostatic cellular recycling mechanism responsible for degrading injured or dysfunctional subcellular organelles and proteins in all living cells. The process of autophagy can be divided into three relatively independent steps: the initiation of phagophore, the formation of autophagosome and the maturation/degradation stage. Different morphological characteristics and molecular marker changes can be observed at these stages. Morphological approaches are useful to produce novel knowledge that would not be achieved through other experimental methods. Here we summarize the morphological methods in monitoring autophagy, the principles in data interpretation and the cautions that should be considered in the study of autophagy.
Autophagy
;
Homeostasis
;
Humans
;
Organelles
;
Phagosomes
9.Recent Research in Inner Ear Homeostasis for Understanding Pathophysiology of Meniere's Disease.
Korean Journal of Otolaryngology - Head and Neck Surgery 2004;47(9):803-811
No abstract available.
Ear, Inner*
;
Homeostasis*
;
Meniere Disease*
10.ATP13A2 and Alpha-synuclein: a Metal Taste in Autophagy.
Tomas LOPES DA FONSECA ; Tiago Fleming OUTEIRO
Experimental Neurobiology 2014;23(4):314-323
Parkinson's Disease (PD) is a complex and multifactorial disorder of both idiopathic and genetic origin. Thus far, more than 20 genes have been linked to familial forms of PD. Two of these genes encode for ATP13A2 and alpha-synuclein (asyn), proteins that seem to be members of a common network in both physiological and disease conditions. Thus, two different hypotheses have emerged supporting a role of ATP13A2 and asyn in metal homeostasis or in autophagy. Interestingly, an appealing theory might combine these two cellular pathways. Here we review the novel findings in the interaction between these two proteins and debate the exciting roads still ahead.
alpha-Synuclein*
;
Autophagy*
;
Homeostasis
;
Parkinson Disease