1.Granulocyte Colony-Stimulating Factor-Induced Psoriasiform Dermatitis Improved by Narrowband Ultraviolet B.
Min Soo JANG ; Jong Bin PARK ; Joon Hee KIM ; Myeong Hyeon YANG ; Kang Hoon LEE ; Sang Hwa HAN ; Kee Suck SUH
Annals of Dermatology 2017;29(2):232-233
No abstract available.
Dermatitis*
;
Granulocytes*
2.Phase II clinical trial of recombinant human granulocyte colony-stimulating factor(fhG-CSF)(KRN8601) in advanced cancer patients with myelosuppression after chemotherapy.
Jae Kyung ROH ; Jin Hyuk CHOI ; Kyung Hee LEE ; Hye Ran LEE ; Nae Choon YOO ; Joo Hang KIM ; Byung Soo KIM ; Ho Young LIM
Journal of the Korean Cancer Association 1993;25(5):725-735
No abstract available.
Drug Therapy*
;
Granulocytes*
;
Humans*
3.The effect of granulocyte colony stimulating facto(G-CSF) in a patient with propylthiouracil-induced agranulocytosis.
Kwang Hyen YOU ; Seung Si SON ; Seung Yel SONG ; Myoung Seon PARK ; Yong Gu LEE ; Chung Gu CHO
Journal of Korean Society of Endocrinology 1993;8(3):347-350
No abstract available.
Agranulocytosis*
;
Granulocytes*
;
Humans
4.To evaluate the efficacy of transfusion of white blood granulocyte mass for treating severe burn with bacterial infection and intoxication associated with leucopenia
Journal of Practical Medicine 2003;454(6):26-28
83 burn patients with the syndrome of bacterial infection and intoxication associated with leucopenia were divided in to 2 groups, the one of 32 patients without transfusion of white blood granulocyte, the other 51 patients with a transfusion rich with neutrophile leucocyte. Results: In the group of the syndrome of severe bacterial infection and intoxication associated with leucopenia, 39.2% have had complication, less than no transfusion group (68.7%). Mortality of the transfusion group: 82.4%, is higher than no transfusion group: 40.6%
Burns
;
Bacterial Infections
;
Granulocytes
5.Efficacy of recombinant human granulocyte colony-stimulating factor(neutrogin) for chemotherapy induced neutropenia in patients with advanced lung carcinoma.
Nae Choon YOO ; Joo Hang KIM ; Yi Young LEE ; Se Kyoo KIM ; Sung Kyoo KIM ; Won Young LEE ; Bong Soo CHA ; Jin Hyuk CHOI ; Ho Young LIM ; Jae Kyung ROH ; Byung Soo KIM
Journal of the Korean Cancer Association 1993;25(2):236-246
No abstract available.
Drug Therapy*
;
Granulocytes*
;
Humans*
;
Lung*
;
Neutropenia*
6.Unusual Morphology of Eosinophil Nucleus: Presented with Double Chromatin Filament Bridge: Report of Three Cases.
Ae Seek KIM ; Young Hee KONG ; Ji Youn KIM
Korean Journal of Clinical Pathology 1998;18(2):122-125
We found an unusual morphology of eosinophil nucleus having longer chromatin filament in addition to a single narrow chromatin bridge. The nucleus having two chromatin filament bridge looked like two legged eosinophil, instead of usual glasses shape. As the physiologic function of the nucleus of granulocyte segmentation and the mechanism by which the lobes are formed during differention is still unknown, we could not know the definite nature and significance of these double chromatin filament. However we could suggest that they may be a reactive change of eosinophilia. This not uncommon morphology has not been described as yet. Here we report three cases of unusual morphology of eosinophil nucleus presenting double chromatin filament bridge, one case with a band form nucleus looked like ring shape, with brief review of literatures.
Chromatin*
;
Eosinophilia
;
Eosinophils*
;
Eyeglasses
;
Glass
;
Granulocytes
;
Leg
7.Two cases of congenital agranulocytosis treated with recombinant human granulocyte colony-stimulating factor.
Byoung Ho CHA ; Seung Hwan OH ; Chukl Joo LYU ; Chang Hyun YANG ; Kir Young KIM
Korean Journal of Hematology 1992;27(2):325-329
No abstract available.
Agranulocytosis*
;
Granulocyte Colony-Stimulating Factor*
;
Granulocytes*
;
Humans*
8.Is Adsorptive Granulocyte and Monocyte Apheresis Effective as an Alternative Treatment Option in Patients with Ulcerative Colitis?.
Gut and Liver 2017;11(2):171-172
No abstract available.
Blood Component Removal*
;
Colitis, Ulcerative*
;
Granulocytes*
;
Humans
;
Monocytes*
;
Ulcer*
9.Late Onset Agranulocytosis with Clozapine Associated with HLA DR4 Responding to Treatment with Granulocyte Colony-stimulating Factor: A Case Report and Review of Literature.
Aakanksha SINGH ; Sandeep GROVER ; Pankaj MALHOTRA ; Subhash C VARMA
Clinical Psychopharmacology and Neuroscience 2016;14(2):212-217
Agranulocytosis as a side effect of clozapine has been reported to be associated with initial phases of treatment, i.e., first six months. Agranulocytosis with clozapine during the initial phases of treatment has been linked to genetic vulnerability in the form of variations in the human leukocyte-antigen haplotypes. However, there is limited literature on late onset agranulocytosis with clozapine and this has very rarely been linked to human leukocyte-antigen haplotypes vulnerability. In this report we review the existing data on late onset agranulocytosis with clozapine and describe the case of a young man, who developed agranulocytosis with clozapine after 35 months of treatment and was found to have genetic vulnerability in form of being positive for HLA DR4. This case highlights underlying autoimmune immune mechanism in clozapine-induced agranulocytosis and the need for frequent blood count monitoring on clozapine even after the initial 6 months of starting treatment especially in patients with genetic vulnerability to develop this condition.
Agranulocytosis*
;
Clozapine*
;
Granulocyte Colony-Stimulating Factor*
;
Granulocytes*
;
Haplotypes
;
Humans
;
Neutropenia
10.A Comparative Study of Biological and Analytical Variabilities in Automated Blood Cell Analysis.
Sae Yun BAIK ; Yun Sik KWAK ; Wee Gyo LEE ; Bong Hak HYUN
Korean Journal of Clinical Pathology 1998;18(4):501-505
BACKGROUND: The National Committee for Clinical Laboratory Standards (NCCLS) recommends that the analytical variability must not exceed 25% of the biological variability in automated blood cell analysis. This study was conducted to determine whether routine automated blood cell analysis by Coulter STKS (Coulter Corp., Miami, FL, U.S.A) comforms with the NCCLS's recommendations. METHODS: Routine CBC analysis with STKS was performed on 22 healthy volunteers. The tests included calculating WBC, RBC, hemoglobin, MCV, platelet, MPV, and percentages of the granulocytes, lymphocytes, and monocytes. Blood samples were collected twice in one week interval to study the total variability. For the analytical variability, blood samples from 12 subjects were tested twice immediately after venipuncture for within-run variability, and samples from 10 subjects were tested immediately and 6 hours after venipuncture for within-day variability. The analytical variability was calculated as the sum of within-run and within-day variabilities. The biological variability was calculated by subtracting the analytical variability from total variability. The ratios of analytical and biological variabilities were calculated by dividing the analytical variability by the biological variability. RESULTS: Ratios of analytical and biological variabilities were as follows: 0.22 for WBC, 0.20 for RBC, 0.21 for hemoglobin, 0.39 for platelet, 1.98 for MPV, 0.07 for %granulocyte, 0.11 for %lymphocyte, and 1.81 for %monocyte. The ratio for MCV was not obtained because the analytical variability exceeded total variability. CONCLUSIONS: The analytical variability did not exceed 25% of the biological variability in all test categories except platelet, MPV and the percentage of monocyte. Thus, it is recommended that the analytic variability of all test categories be reduced so as to be in conformity with the NCCLS' recommendations.
Blood Cells*
;
Blood Platelets
;
Granulocytes
;
Healthy Volunteers
;
Lymphocytes
;
Monocytes
;
Phlebotomy