A study on the morbidity rate of gonorrhea in Hanoi hospital of Dermatology and Venerology has shown that the rate of isolated gonococcus (neisseria gonorrheae) were 14.31%. This rate in male was higher than this in female. The morbidity rate of receptionist much higher than this than this of others.
Gonorrhea ; Epidemiology

From Nov. 1999 to April 2000, at Ha Noi Centre of Vereno-Dermatology, 365 samples isolated from patients of all ranges of age were studied, using the procedures of antibiogramme to determine the sensitivity of antibiotics to blennorrhagic agent. Results: 65 positive cases (17.8%), among them patients aged 16-40 account for highest positive rate (27.3%). Gonococcus has relatively high resistance to Penicillin (75.4%), then tetracyclin (21.5%), ciprofloxacin (6.2%). The resistance to Kanamycin (18.5%), Nalidizic acide (10.8%), Chloramphenicol (7.7%), Erythromycine (1.5%) were recorded. Multiresistance to 2 antibiotics had the highest rate: PG-TE (16.9%), PG-KA (15.4%), to 3 antibiotics PG-KA-NA (4.6%) was noted. There is no resistance to Ceftriaxon, Spectinomycin, Cephalexin
Neisseria gonorrhoeae ; Neisseria ; Gonorrhea

A total of forty eight (48) patients had consulted the clinic, 38 or 79.16% are symptomatic and 10 or 20.84% has none. These patients came in for various reasons like having a urethral discharge, dysuria, being named as contact, for routine check-up, follow up after self medication and/or empirical treatment. They underwent two methods of collection. The first is the slide-to-urethra which has a higher isolation rate compared with the swabbing method which has a lower rate in the detection of gonorrhea thru gram method.

In the year 2000, in the Institute of Dermato-Venerology 157 of 1323 suspected patients (11.87%) were isolated from culture. By agar dispersion technique, antibiogramme showed that 47.77% were resistant to penicillin, 44.52% to tetracyclin and 42.67% to ciprofloxacine. 100% of isolated strains were well sensitive to cephalosporine of 3rd generation and to spectinomycine
Anti-Bacterial Agents ; Gonorrhea ; Neisseria

Diagnostic ; Neisseria ; Gonorrhea ; Comparative Study

Between September to October 1985, 61 male patients with uncomplicated genital gonorrhea, including 33 PPNG urethritis, were treated with single oral dose of rosoxaci, a new oral quinolone derivative, 300 mg Fifty-three patients returned for a test of cure 3 5 days after the treatment. When a patient was found to be not cured, a second course of treatment was given and followed as above. The overall failure rate of initial treatment was 11.3%(6/53). It was 15. 2%(5/33) for PPNG urethritis and 5%(1/20) for non-PPNG urethritis. During the course of this trial the rate af PPNG among pretreatment isolates was exceptionally high(62.2g) compared to 277. during the period of 198l~4. If the PPNG prevalance rate had been a little lower, for instance 30g the overall failure rate would have been much lower(4.9%). When the second treatment was given to the failure cases 4-6 days after the first treatment. The overall failure rate dropped to 3.8%, 3.1% for PPNG urethritis and 5.0% for non-PPNG urethritis. Ten patients (2l, 3p,) developed postgoriococcal urethritie. Susceptibility test, with disks containing rosoxacin 5mcg, showed the inhibition zone to be greater than 34mm. Eight patients developed minor side effects: dizziness or gastritis. The rosoxacin, oral dose of 300 mg, regimen gave the best result yet by oral treatment for gonorrheae in recent years in Korea.
Dizziness ; Gastritis ; Gonorrhea ; Humans ; Korea ; Male* ; Urethritis*

Ofloxacin, one of the new quinolone derivatives, is found to be highly effective against both PPNG and non-PPNG urethritis. The objective of this trial was to establish the efficacy of two ofloxacin regimens in the treatment of uncomplicated male gonococcal urethritis. A total of 138 patients with uncomplicated gonococcal urethritis seen at the VD Clinic, Choong-Ku Public Health Center, in Seoul in the period of March Jun 1988, were subjected to this study. The patients were divided randomly into two groups and assigned to one of two treatment regimens of afloxacin, 400mg, PO and 200mg, PO, twice a day for 2 days. No failure case was seen in both groups. Both of these ofloxacin regimens were found to be highly effective and safe in the treatment of gonococcal urethrithis. It is suggested that, because of high rate of PPNGs among circulating N. gonorrhoeae, they can be recommended as the first line treatment for gonorrhea in Korea.
Gonorrhea ; Humans ; Korea ; Male* ; Ofloxacin* ; Public Health ; Seoul ; Urethritis*

BACKGROUND: Although the culture of urethral discharge using a cutton swab is regarded as one of the most sensitive and reliable diagnostic methods of gonorrhea, it may give pain or diagnostic methods of gonorrhea, it may give pain or discomfort to patients, and its detection rate may be influenced by the examiner's technical ability. OBJECTIVE: The purpose of this study was to compare the positive culture rates between ure4thral discharge and urinary sediment for the diagnosing of Neisseria gonorrheae. METHODS: We compared this technique with the culture of urethral discharge using the specimens from 357 male patients with gonococcal infection at VD clinic of Jungku Pvblic Health center in Seoul from Jan 1991 to Jun 1993. RESULTS: The culture of urinary sediment was positive in 339 of 357(94.95), whereas the culture of urethral discharge was positive in 346 of 357(96.95). However, these data have no statistical significance(P<0.05). The obe observed sensitivity and specificity of culture of urinary sediment comjpared to culture of urethral discharge were 97.75 and 90.9%, respectively. The predictive value of positive and negative test compared to the culture of urethral discharge were 99.7% and 55.65, respectively. As our data showed low negative predictive value, a negative culture result of urinary sediment does not always imply a negative culture result of urethral discharge. CONCLUSION: Therefore, at present, the previous method of the culture of urethral discharge is more highly recommended and further studies for this diagnostic and/or new method of gonorrhea based on larger group of patients is encouraged.
Gonorrhea ; Humans ; Male ; Neisseria gonorrhoeae* ; Neisseria* ; Sensitivity and Specificity ; Seoul

The treatment of gonorrhea caused by beta-strains of N. gonorrhoeae is quite different from that of non-beta-strains, but it is not always possible in general practice to take cultures of gonococci to detect p-lactamase producing organisms. Therefore treatment regimens commonly used for gonorrhoea should be effective against both PPNG non-PPNG strains. Eighty-seven male uncomplicated gonorrheal patients were treated with intramuscular kanarnycin 2gm in combilnation with talampicillin 2. 5 gm plus probenecid 1grn orally. Sixty-seven patients were followed up. All patients recovered. Ten patients among sixty-seven patients had PPNG. A regimen of intramuscular kanamycin 2 gm, talampicillin 2. 5 gm plus probenecid 1 0 gm orally seems to be one of the most cost effective regimens in Korea.
General Practice ; Gonorrhea* ; Humans ; Kanamycin* ; Korea ; Male* ; Probenecid ; Talampicillin*

BACKGROUND: In recent years gonorrhea has been panendemic and remains one of the most common STDs in the world, especially in developing countries. OBJECTIVE & METHOD: For the detection of a more effective teripeutic regimen and assessing the prevalence of PPNG, will have been trying to study the paieits who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. RESULTS: In 1993, 187 strains of N. gonorrhoeae were isolated, ar, ong which 139(74.3%) were PPNG. CONCLUSION: Our results suggests that the prevalence of PPNG in Seoul is still increasing.
Developing Countries ; Gonorrhea ; Prevalence* ; Public Health ; Seoul* ; Sexually Transmitted Diseases