We constructed the family tree database (DB) by using a new family code system that can logically express interpersonal family relationships and by comparing and complementing health insurance eligibility data and resident register data of the National Health Information Database (NHID). In the family tree DB, Parents and grandparents are matched for more than 95% of those who were born between 2010 and 2017. Codes for inverse relationships and extended relationships are generated using sequences of the three-digit basic family codes. The family tree DB contains variables such as sex, birth year, family relations, and degree of kinship (maximum of 4) between subjects and family members. Using the family tree DB, we find that prevalence rates of hypertension, diabetes, ischemic heart disease, cerebrovascular disease, and cancer are higher for those with family history. The family tree DB may omit some relationships due to incomplete past data, and some family relations cannot be uniquely determined because the source data only contain relationships between head and members of the household. The family tree DB is a part of the NHID, and researchers can submit requests for data on the website at http://nhiss.nhis.or.kr. Requested data will be provided after approval from the data service review board. However, the family tree DB can be limitedly provided for studies with high public value in order to maximize personal information protection.
Cerebrovascular Disorders ; Complement System Proteins ; Computer Security ; Family Characteristics ; Family Relations ; Grandparents ; Head ; Humans ; Hypertension ; Insurance, Health ; Interpersonal Relations ; Korea ; Logic ; Myocardial Ischemia ; Parents ; Parturition ; Pedigree ; Prevalence

Background: The family life cycle describes the stages of family development starting from the formation of the emerging adults to marriage, birth of children, growth into adolescents, adulthood and families in later life. The cycle includes individual developmental changes of family members, evolution of marital relationship and cyclic development of the evolving family unit. Presently, there is no study that describes the developmental tasks, structures and functions of Filipino families with young children. Objective: The objective of the study was to describe the developmental tasks, family structure and functions among selected Filipino families with young children. Methods: A cross-sectional study was conducted from January to March 2016 on a total of 353 Filipino parents of families with young children ages 0-12 years old. Results: The extended type of family (65%) is more predominant than the nuclear type (35%) among the participants. A high Family APGAR score of 9.2 (SD ± 1.1) translated to highly functioning families with young children. Overall, the first order changes on financing, marital adjustments and extended family relationships were highly met except that on the unexpected costs of family life. For second order changes, there was a significant association of decline in intimacy over time among couples progress thru the life stages (X2 12.75, p-value 0.013). Partners were able to adjust the marital relationship mainly through communication and acceptance. The parenting roles were done most of the time except for the roles on inspiring children for nationalism and providing wholesome educational materials. Finally, almost all families with young children (99%) were able to align relationship with extended family members. Conclusion The selected Filipino families with young children mostly have an extended family structure and are highly functional. Overall, the first and second developmental tasks were accomplished in varying degrees.
Family ; Family Relations ; Parenting

BACKGROUND: The goals of this study are to investigate the propensity to depression and anxiety in children, and also, to investigate its relationship to the family structure, their life events, and school achievement. We have attempted to aid the continuous and comprehensive management of children with depression and anxiety in a field of family practice. METHODS: A group of 797 boys and girls in 5th and 6th were selected grades a elementary school in their, In the area of ll-san and In-cheon city in August, 1997. Making use of the Kovacs' Children's Depression Inventory(CDI, 1977) and the Spielberger's State-Trait Anxiety Inventory for Children(STAIC, 1973), we investigated the propensity to depression and anxiety by self-rating. At the same time, the general characteristics(gender, age, resideuce, family structure), life events(death single parent, divorced family, death of a sibling, family discord between husband), and school achievement were investigated and assessed their relationship. RESULTS: The Children's Depression Inventory score was 11.69, the State Anxiety Inventory score was 31.51, and the Trait Anxiety Inventory score was 31.49. The CDI score were significantly higher in females, sixth year students, residents execpt for those living in an apartment or villa, and low school achievement group(P<0.01, P<0.05), There was no significance between CDI score and age, whether or not a dual-income family, death of a sib, hospitalization within 6 months, and family discord between husband and wife. The STAIC score was significantly higher for old age, female, sixth year students, and low school achieve menu group(P<0.01), and there was no significance between the STAIC score and residence, whether or not a dual-income family, death of a sibling, hospitalization within 6 months, and family discord between husband and wife. CONCLUSIONS: According to our results, there was a significant correlation between gender, school years, school achievement and a propensity to depression and anxiety. Therefore, family physician should be more involved in family intervention and anticipatory guidance upon medical examination and treatment, if he or she has a symptoms of anxiety and depression.
Anxiety* ; Child* ; Depression* ; Divorce ; Family Practice ; Female ; Hospitalization ; Humans ; Incheon ; Physicians, Family ; Siblings ; Single Parent ; Spouses

PURPOSE: This cross-sectional study was done to compare factors influencing young adolescents' aggression according to family structure. METHODS: Participants were 680 young adolescents aged 11 to 15 years (113 in single father families, 136 in single mother families, 49 in grandparent families, and 382 in both-parent families). All measures were self-administered. Data were analyzed using SPSS 18.0 program and factors affecting young adolescents' aggression were analyzed by stepwise multiple regression. RESULTS: Levels of young adolescents' aggression and all variables were significantly different among the four family structure groups. Factors influencing young adolescents' aggression were also different according to these 4 groups. For single father families, depression-anxiety and family hardiness significantly predicted the level of young adolescents' aggression (adjusted R square=.37, p<.001). For single mother families, depression-anxiety, gender, and friends' support significantly predicted the level of young adolescents' aggression (adjusted R square=.58, p<.001). For grandparent families, depression-anxiety and family support significantly predicted the level of young adolescents' aggression (adjusted R square=.58, p<.001). For both-parent families, depression-anxiety, family hardiness, and friends' support significantly predicted the level of young adolescents' aggression (adjusted R square=.48, p<.001). CONCLUSION: Nurses working with young adolescents should consider family structure-specific factors influencing aggression in this population.
Adolescent ; *Adolescent Psychology ; *Aggression ; Anxiety ; Child ; Cross-Sectional Studies ; Depression ; Family ; Family Relations ; Female ; Humans ; Male ; Questionnaires ; Sex Factors ; Single-Parent Family ; Social Support

Family Characteristics, Social Problems, Divorce

PURPOSE: The study was done to influence of family function and degree of depression on impulsive behavior in adolescents. METHOD: Using convenience sampling 780 adolescents were recruited from October 29 and November 9, 2011. Data were collected using self-report questionnaires which included items on general characteristics, family function, depression, and impulsive behavior. Data were analyzed using t-test, ANOVA, Scheffe test, Pearson Correlation Coefficient, and hierarchical regression analysis. RESULTS: The major findings of this study were as follow; 1) There was a significant negative relationship between family function and impulsive behavior (r=-.236, p<.001) and a positive relationship between depression and impulsive behavior (r=.342, p<.001). 2) Factors with a significant negative association with impulsive behavior were higher school records (beta=-.112, p<.001) and family function: positive resolution of family problems (beta=-.213, p=.008), while a significant positive association was found for unsatisfactory school life (beta=.103, p=.016), family function: emotional reactivity (beta=.159, p=.028), and depression (beta=.301, p<.001). These variables explained 20.1% of variance for impulsive behavior. CONCLUSION: The results of this study identify a relationship between family function, depression, and impulsive behavior in adolescents indicating variables to be addressed to reduce impulsive behavior. These variables can be used in developing intervention programs.
Adolescent ; Depression ; Family Characteristics ; Family Relations ; Humans ; Impulsive Behavior ; Surveys and Questionnaires

PURPOSE: This study was done to identify the relationship of family function, self-efficacy and self-leadership, and to identify factors affecting self-leadership in adolescents. METHOD: Sampling was done using a convenience sampling method and 779 adolescents were recruited between June 4 and 15, 2012. Data were collected using self-report questionnaires which included general characteristics, family function, self-efficacy and self-leadership. Data were analyzed using descriptive, t-test, one way ANOVA, Scheffe test, Pearson correlation coefficient, and stepwise regression analysis with SPSS/WIN 19.0. RESULTS: The major findings of this study were as follow; 1) There were significant relationships between self-leadership and family function (r=.36, p<.001), and self-efficacy (r=.51, p<.001). 2) Self-leadership was significantly associated with self-efficacy (beta=.42, p<.001), family function (beta=.20, p<.001), satisfactory relationships with teachers (beta=.12, p<.001), experience as a leader (beta=.10, p=.001), higher school records (beta=.17, p<.001), and medium school records (beta=.11, p=.001). These variables explained 40.4% of variance in adolescents' self-leadership. CONCLUSION: The results of this study indicate that there is a relationship between family function, self-efficacy and self-leadership in adolescents and that in developing intervention programs to promote self-leadership, in adolescents, these variables should be considered.
Adolescent ; Family Characteristics ; Family Relations ; Humans ; Leadership ; Surveys and Questionnaires ; Self Efficacy

OBJECTIVES: Two related cases of Hemolytic-Uremic Syndrome (HUS) were reported to the Korea National Institute of Health in May, 2001. Shiga toxin 2 genes were detected in both stool samples. We suspected an enterohemorrhagic Escherichia coli (EHEC) infection as the cause of the HUS, and conducted an investigation to find the source of the infection and its route of transmission. METHODS: We performed case investigations on these two related HUS cases, and obtained interviews and rectal swabs form the family members and other close contacts. Additionally, we performed rectal swabs on the cattle raised by the household of the index patient. RESULTS: We found a 20 month old index patient and a 6 year-old cousin had developed HUS, where there had been a 2 day history of contact with the index, and bacteriological examinations for these two patients revealed, indistinguishably, the same E. coli O171. The grandmother of the index patient was found to be asymptomatic, but E. coli O26 was isolated. We also found a probable case in the mother of the cousin. She reported a history of contact with the index, and developed bloody diarrhea of 3 days duration. The test results for the cattle revealed E. coli O26 in one cow, and E. coli O26 and O55 in another. E. coli O26, which was isolated in both cows and the grandmother of the index, were indistinguishably the same. CONCLUSIONS: We found that the E. coli O26 in the grandmother had originated from the cows, and that the E. coli O171 found in the index patient had been transmitted to the cousin through person-to-person contact.
Animals ; Cattle ; Diarrhea ; Enterohemorrhagic Escherichia coli* ; Family Characteristics ; Grandparents ; Hemolytic-Uremic Syndrome ; Humans ; Korea* ; Mothers ; Shiga Toxin 2 ; Zoonoses

Aggrecan is a proteoglycan in the extracellular matrix of growth plate and cartilaginous tissues. Aggrecanopathy has been reported as a genetic cause not only for severe skeletal dysplasia but also for autosomal dominant short stature with normal to advanced bone age. We report a novel heterozygous mutation of ACAN in a Korean family with proportionate short stature identified through targeted exome sequencing. We present a girl of 4 years and 9 months with a family history of short stature over three generations. The paternal grandmother is 143 cm tall (−3.8 as a Korean standard deviation score [SDS]), the father 155 cm (−3.4 SDS), and the index case 96.2 cm (−2.9 SDS). Evaluation for short stature showed normal growth hormone (GH) peaks in the GH provocation test and a mild delayed bone age for chronological age. This subject had clinical characteristics including a triangular face, flat nasal bridge, prognathia, blue sclerae, and brittle teeth. The targeted exome sequencing was applied to detect autosomal dominant growth palate disorder. The novel variant c.910G>A (p.Asp304Asn) in ACAN was identified and this variant was found in the subject's father using Sanger sequencing. This is the first case of Korean familial short stature due to ACAN mutation. ACAN should be considered for proportionate idiopathic short stature, especially in cases of familial short stature.
Aggrecans ; Exome ; Extracellular Matrix ; Family Characteristics ; Fathers ; Female ; Grandparents ; Growth Hormone ; Growth Plate ; Humans ; Palate ; Proteoglycans ; Sclera ; Tooth

BACKGROUND: Patients with parkinsonism exhibit motor symptoms, cognitive impairment, and neuropsychiatric changes, and these symptoms increase caregiver burden. Family dynamics can be influenced by the presence of comorbidities, which is especially important in diseases causing caregiver burden. We investigated the effects of spousal parkinsonism on family functioning and communication. METHODS: Couples without parkinsonism, who visited hospital-based family practices, were recruited by 28 family physicians from 22 hospitals between April 2009 and June 2011; patients with parkinsonism and their spouses were recruited from a single institution. The participants completed questionnaires on demographic characteristics, lifestyle factors, family functioning (the Korean version of the Family Adaptation and Cohesion Evaluation Scale [FACES] III), and family communication (the Family Communication Scale of the FACES-IV). We compared family functioning and communication between spouses of the patients with and without parkinsonism. RESULTS: The mean family adaptability and cohesion scores of the spouses of the patients with parkinsonism were 23.09±6.48 and 32.40±8.43, respectively, whereas those of the control group were 23.84±5.88 and 34.89±7.59, respectively. Family functioning and family communication were significantly different between the spouses of individuals with and without parkinsonism. After adjusting for age, sex, income, and cardiovascular disease in the logistic regression analysis, family functioning was found to significantly deteriorate in the spouses of patients with parkinsonism but not the control group. Family communication decreased significantly in spouses of patients with parkinsonism. CONCLUSION: Family functioning and family communication significantly deteriorated in spouses of patients with parkinsonism.
Cardiovascular Diseases ; Caregivers ; Comorbidity ; Family Characteristics ; Family Practice ; Family Relations ; Humans ; Life Style ; Logistic Models ; Neurobehavioral Manifestations ; Parkinsonian Disorders* ; Physicians, Family ; Spouses*