No abstract available.
Autoimmunity* ; Hypothyroidism* ; Thyroid Gland*

No abstract available.
Animals ; Autoimmunity* ; Mice*

The immune status in 26 typhoid fever patients has been studied. They are 15 males, 112 females from 16 to 30 years old. This study reveals that: during the fever period of the disease, pronounced disturbances in immune, homeostasis are observed, which are manifested by lymphopenia, with a considerable rise of natural killer (NK) and active rosette forming cells (Ea). At the period of convalescence, the parameters decreased to normal value, except a mild increase of immunoglobulin (IgM, IgG)
Typhoid Fever ; Autoimmunity

40 out of 50 subjects bitten by dog/cat were injected completely 4- 6 doses of rabies vaccine. Using ELISA, the authors found that 42.5% of serum samples that taken after injecting 4 doses of rabies vaccine had antibody titer 0.5IU/ml, met the WHO’s minimum requirement. The GMT was 2.71IU/ml. 62.5% of serum samples taken after injecting 6 doses of rabies vaccine had antibody titer 0.5IU/ml. The GMT was 3.14EU/ml
Immune System ; Vaccines ; Rabies ; Autoimmunity

40 out of 50 subjects bitten by dog/cat were injected completely 4- 6 doses of rabies vaccine. Using ELISA, the authors found that 42.5% of serum samples that taken after injecting 4 doses of rabies vaccine had antibody titer ³0.5IU/ml, met the WHO’s minimum requirement. The GMT was 2.71IU/ml. 62.5% of serum samples taken after injecting 6 doses of rabies vaccine had antibody titer ³0.5IU/ml. The GMT was 3.14EU/ml.
Immune System ; Vaccines ; Rabies ; Autoimmunity

Neutrophils are the most abundant white blood cells in the peripheral blood and have long been recognized as the major phagocytes in acute infection by destroying extracellular pathogens. Although research on neutrophils hampered by intractability in the experiments, the newly discovered effector functions of neutrophils includes granular proteins, and cytokines, extracellular traps. With all effector mechanism neutrophils play a critical role in the pathogenesis of acute and chronic infection, autoimmunity and cancer.
Autoimmunity ; Cytokines ; Inflammation ; Leukocytes ; Neutrophils ; Phagocytes ; Proteins

PURPOSE: The etiology of chronic nonbacterial prostatitis is unclear but it appears to be either an infectious disease caused by yet unidentified pathogens or a noninfectious form of inflammation. But, recent data showed that the chronic nonbacterial prostatitis is developed from abnormalities in autoimmunity. We examined the serum CD4, CD8, CD4/CD8 and CD16 levels in patients with chronic nonbacterial prostatitis and normal volunteers, so we tried to reveal their differences in both two groups and the relationship of its pathogenesis. MATERIALS AND METHODS: Between Aug. 1996 and Nov. 1996, we examined the serum level of CD4, CD8 and CD16 in patient with chronic nonbacterial prostatitis(n=20) and in normal patients including volunteers(n=16). RESULTS: The results showed decreased CD4, and increased CD8 which lead to decreased CD4/CD8 ratio and normal CD16 levels. CONCLUSIONS: We believe that our experimental data would show changes of T-cell subclones in chronic nonbacterial prostatitis patients and suggest the basic data in understanding the etiology of chronic nonbacterial prostatitis.
Autoimmunity ; Communicable Diseases ; Healthy Volunteers ; Humans ; Inflammation ; Prostatitis* ; T-Lymphocytes*

Clinical manifestations of hypothyroidism are very various and these degree are related to the severity and duration of the disease. Pericardial effusions, one of the manifestations of hypothy-roidism, were relatively common in the past. However, recently they may not be so frequent representative of hypothyroid subjects. The higher frequency of Hashimotos thyroiditis in Turners syndrome, especially those with an X-isochromosome, compared with the general population is well known. The pathophysiological process of autoimmunity is thought to be linked with the presence of an abnormal X-chromosome. Recently we experienced a case of X-isochromosome Turners syndrome with hypothyroidism and pericardial effusion and report it with reviews of the literatures.
Autoimmunity ; Hypothyroidism* ; Pericardial Effusion* ; Thyroid Gland ; Thyroiditis ; Turner Syndrome*

Autoimmunity ; Humans ; Immunity, Innate ; Liver Cirrhosis, Biliary ; immunology

Myasthenia gravis is relatively rare disease which is related autoimmune response. There are various methods of management for myasthenia gravis, but nowaday radical thymectomy is the treatment of choice in the aspect of bringing out complete remission and clinical improvement. Sixteen patient of myasthenia gravis underwent radical thymectomy during last eight years, and its result was analyed. Complete remission was achieved in five patients(31 %) and pharmacological or symptomatic improvement in seven patients(44 %), thus giving a total remission in 12 patients(75 %). Postoperative result was not correlated with age, sex, degree of preoperative symptom, surgical approach, pathologic diagnosis.
Autoimmunity ; Diagnosis ; Humans ; Myasthenia Gravis* ; Rare Diseases ; Thymectomy