1.Clinical study on validation systemic inflammatory response syndrome score in predicting prognosis in acute craniocerebral trauma
Zhijun ZHU ; Wen HUANG ; Yi OUYANG
Chinese Journal of Postgraduates of Medicine 2008;31(29):18-20
Objective To explore the effect and significance of systemic inflammatory response syndrome(SIRS )score in predicting prognosis in acute craniocerebral trauma. Methods The clinical data of 620 patients were collected at admission from January 2003 to December 2007, GCS and SIRS score were calculated in 24 hours.The relation of the mortality rates and GCS score were analyzed in different SIRS score patients by controlling age. Results With SIRS score increasing,mortality rates increased as well,and pa-tients with SIRS (score≥2) mortality rates had significantly higher,and also in the same age and GCS score group.Mortality rotes were significant in staifistics (P<0.05). Conclusion SIRS score is significant inde-pendent predicting prognosis in acute craniocerebral trauma and in clinic.
2.CT evaluation of hepatocellular carcinomas supplied by right inferior phrenic arteries
Ming WEN ; Mingxia ZHU ; Yonghuo HUANG
Chinese Journal of Radiology 1994;0(06):-
Objective To evaluate the CT appearance of the hepatocellular carcinomas (HCC) supplied by the right inferior phrenic arteries (RIPA). Methods A total of 195 consecutive cases of HCCs examined with helical CT and arteriography were studied. 15 proven HCCs cases were supplied by the RIPA. On arterial phase CT images, the size of the RIPA, the left inferior phrenic arteries, and HCCs were measured, and the origin of RIPA and the location of HCCs were recorded. The CT findings in these 15 cases were correlated with arteriographic images. Results CT showed RIPA on the right diaphragmatic crus as high attenuation in all patients. The origin of RIPA was demonstrated in 11 cases. The diameter of the RIPA (3.1?1.1) mm was larger than that of the left inferior phrenic artery (1.3?0.4) mm ( P
3.Predicting cerebral palsy of high risk neonates:A comparative analysis of the validity of general movement assessment and classical neurological motor examination
Jinhua HUANG ; Xiaohong WEN ; Shuiyun WANG ; Yuee ZHU
Chinese Journal of Physical Medicine and Rehabilitation 2011;33(10):755-758
Objective To compare the validity of general movements ( GM ) assessment with that of a 52 item neurological motor examination in predicting cerebral palsy among high risk neonates.Methods Eighty-four infants aged 12 months at high risk were evaluated simultaneously with GM assessment and the 52 item neurological motor examination.The utility of the two methods in predicting cerebral palsy was then compared.Results There were 4 cerebral palsy patients among the 84 high risk neonates.The GM assessment's predictive validity for Monotonous movements was 78.57%,its sensitivity was 25%,its specificity was 81.25%,its positive predictive value was 6.25%,its negative predictive value was 95.59%,and its kappa value was 0.215.The comparable values for the Cramped-synchronised scale were validity 96.43%,sensitivity 50%,specificity 98.75%,positive predictive value 66.67%,negative predictive value 97.53%,and kappa value O.553.The values for the absence of Fidgety movements were validity 98.81%,sensitivity 75%,specificity 100%,positive predictive value 100%,negative predictive value 98.77%,and kappa value 0.851.For the entire 52 items of the neurological motor examination the corresponding values were validity 51.19%,sensitivity 100%,specificity 48.75%,positive predictive value 8.89%,negative predictive value 100%,and kappa value 0.083.Conclusions GM assessment can predict the severe neurological deficits of cerebral palsy among high risk neonates by the age of 12 months.The 52-item neurological motor examination can detect mild and moderate neurological deficits.GM assessment combined with the 52-item neurological motor examination is a desirable and effective way to assess high risk infants.
4.Clinical center-based health management and quality of life of patients with asthma
Wen WANG ; Kewu HUANG ; Qiuyun LIU ; Yaling ZHU ; Chen WANG
Chinese Journal of Health Management 2011;05(4):199-203
Objective To evaluate the effects of clinical center-based health management on quality of life (QOL) of patients with asthma. Methods A total of 642 patients who had received standard antiasthma treatment over 3 years in our clinical center from September 2005 up to now were randomly assigned to the good compliance group ( group A, n = 326 ) and bad compliance group ( group B, n = 316 ). A questionnaire was used to estimate the awareness about asthma,medical therapy and disease control. Levels of QOL were compared at 6 months and 1 and 3 years after health education. Results In group A,uncontrolled,partly controlled, and completely controlled asthma were found in 21%, 47%, and 32% participants, respectively. Significant difference of QOL was shown between the 2 groups after the intervention ( P < 0. 05 ). At 6 months, forced expiratory volume in one second ( FEV1 ), percentage of predicted FEV1 ( FEV1 % pre) ,and peak expiratory flow rate ( PEF)were significantly improved in group A ( all P <0. 05 ),although acute attack and hospitalization were largely reduced. In comparison with baseline,6 months and 1 year,self-reported QOL, limitation of motion, stimulus avoidance and response, and disease concerns were significantly changed at 3 years. Conclusions Clinic center-based health management could benefit disease control and QOL of patients with asthma.
5.MR-guided percutaneous sclerotherapy of venous vascular malformations of the extremities
Xianjin ZHU ; Wu WANG ; Wen HONG ; Zhenguo HUANG ; Xuezhe ZHANG
Chinese Journal of Radiology 2009;43(5):531-534
Objective To prospectively assess the therapeutic procedure and outcome of MR-guided percutaneous sclerotherapy in patients with venous vascular malformations of the extremities. Methods Fifty-seven percutaneous sclerotherapy treatments were performed under MR guidance in 28 patients with venous vascular malformation. Assessment was conducted to analyze (1) individual success of therapy, (2) improvement of clinical symptoms, ( 3 ) occurrence of complications, (4) volume changes at follow-up examinations, (5) contrast-to -noise ration (CNR) changes. Paired-t test was used to compare the volume and CNR of pre- and postintervention. Results All MR-guided percutaneous sclerotherapy were performed successfully and without serious complications. Individual predominant symptoms were improved, especially about the pain and functional impairment. The mean lesion volumes of pre- and post-intervention were (56. 8 ± 11.7 ) cm3 and ( 27.0 ± 7.2 ) cm3 respectively, which showed significant difference ( t = 8. 90, P < 0. 01 ). The percentage of volume shrinkage ranged from 28. 5% to 74. 4% [ mean ( 54. 4 ± 5. 3 ) % ]. The CNR of the pre and post-interventional images were 21.9 ± 2. 0 and 8.4 ± 0. 9 respectively. There was significant difference(t = 21.76, P < 0.01 ) between them, and the percentages of CNR decrease were 40.0% to 78. 0% [ the mean(61.0 ± 3.6)%]. Conclusion MR-guided sclerotherapy of venous vascular malformations of the extremities is a safe and efficient technique.
6.Congenital aortic arch twist abnormality with thoracic aorta aneurysm: a case report.
Wei-hua ZHU ; Wen-bin ZHANG ; Xian-mei HUANG
Chinese Journal of Pediatrics 2005;43(7):540-540
Abnormalities, Multiple
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diagnosis
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diagnostic imaging
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Aorta, Thoracic
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abnormalities
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diagnostic imaging
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Aortic Aneurysm, Thoracic
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congenital
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diagnosis
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diagnostic imaging
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Aortic Diseases
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congenital
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diagnosis
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diagnostic imaging
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Child
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Diagnosis, Differential
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Humans
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Male
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Radiography
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Rare Diseases
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X-Rays
7.Effects of low dose mifepristone on population and subsets of natural killer cells in human endometrium during receptive phase
Hong-Xia ZHU ; Wu-Wen ZHANG ; Li-Li HUANG ;
Chinese Journal of Obstetrics and Gynecology 2000;0(12):-
0.05).Conclusion Low dose mifepristones increase the number of CD_(56)~+ NK cells and the percentage of CD_3~-CD_(56)~+ CD_(16)~-NK subset,which might result in the disturbance of human endometrial immuno-mieroenviromnent during receptive phase and lead to imolantation failure.
8.Comparison of ambulatory and conventional urodynamics in females with stress urinary incontinence
Jianguo WEN ; Wen ZHU ; Li YANG ; Lingang CUI ; Xiaoping SHANG ; Ruili ZHANG ; Jinsheng LI ; Chenxu HUANG
Chinese Journal of Urology 2013;(2):116-119
Objective To compare the application of ambulatory urodynamic(AUM)and conventional urodynamic(CUD)in detecting stress urinary incontinence(SUI)and detrusor overactivity(DO)in females.Methods Incontinence questionnaire short form(ICI-Q-SF),CUD and AUM were administrated on 30 female patients with the mean age of 49.4(32-63)years.The duration of symptom was 4.7 (1-9)years.The patients were divided into 3 groups of mild(n =9),moderate(n =15)and severe (n =6)according to ICI-Q-SF.Three micturition cycles were recorded during AUM.Results SUI and DO detected by AUM were 90% and 37%,significantly more than those by CUD of 70% and 10%(P <0.05).Twenty-one moderate and severe SUI patients diagnosed by ICI-Q-SF,detected by AUM and CUD simultaneously showed that abdominal leak point pressure(ALPP)and voided volume were lower,and detrusor pressure was higher recorded by AUM than those by CUD significantly(P < 0.05).Conclusions SUI and DO are easier detected by AUM than by CUD.AUM is a useful additional tool in clinical practice for those patients CUD failed to explain their symptoms.
9.Angiographic features of infarct-related artery and the therapeutic efficacy of intravenous thrombolysis in patients with acute myocardial infarction
Hanchun WEN ; Jijin ZHU ; Lang LI ; Liguang ZHU ; Zhiheng ZEN ; Kai HUANG ; Yongwei YE ; Shiwen LU
Chinese Journal of Emergency Medicine 2011;20(3):283-286
Objective To evaluate the angiographic findings and the therapeutic effect of thrombolysis in AMI (acute myocardial infarction) patients. Method A retrospective study were carried out in consecutive eighty-four inpatients with AMI treated with intravenous thrombolysis and coronary angiography was taken within a week after illness onset from January 2000 to August 2007. The patients were divided into successful recanalization group and non-recanalization group. Single factor χ2 test and multi-factor logistic regression analysis were applied to observe the relationship among the angiographic features of IRA (infarct-related artery including the number of stnosis, the location of stenosis, the severity of stenosis and the morphological changes) and treatment effect of intravenous urokinase thrombolysis. Results (1) Single factor χ2 test showed that location and the extent of lesion of IRA were eligible to enter the logistic regression formula (P < 0.05),whereas the number of lesions and the severity of IRA's stenosis were not eligible to enter the logistic regression formula (P > 0. 05). (2) Multi-factor logistic regression analysis showed that the extent of lesion of IRA was the only factor that had a negative impact on the therapeutic effect of intravenous thrombolysis.Conclusions The study shows that the extent of lesion of IRA is the only factor that has a negative impact on the therapeutic effect of intravenous thrombolysis; The number, the location of lesion and the severity of stenosis of IRA have no impact on the therapeutic effect of intravenous thrombolysis in AMI.
10.Assessment of right ventricular function in patients with right ventricular overload using real-time three-dimensional echocardiography
Ting XU ; Yuwen JIANG ; Wen ZHU ; Hui ZHU ; Guoqian HUANG ; Yong LI
Chinese Journal of Ultrasonography 2016;(1):7-11
Objective To evaluate global and segmental right ventricular ( RV ) systolic functions in patients with excessive volume or pressure load using real‐time three‐dimensional echocardiography ( RT‐3DE) . Methods Forty‐five patients with RV volume overload ,45 patients with RV pressure overload and 45 healthy subjects were underwent RT‐3DE . RV global and segmental ( inflow ,body ,outflow ) end‐diastolic volume (EDV) ,end‐systolic volume (ESV) ,stroke volume (SV) and ejection fraction (EF) were analyzed with TomTec software . The correlations between EF with the three‐dimensional method and two‐dimensional parameters including right ventricle systolic pressure( RVSP) were discussed . Results Global EDV and ESV increased significantly in both patient groups compared with controls ( all P < 0 .05) ,but there was no difference between two patient groups ( P >0 .05) .Compensated increase of SV was found in sixty percent of patients with volume overload but none with pressure overload ( P < 0 .05) . Global EF decreased significantly in both of patient groups (all P <0 .05) ,which was more significant patients with pressure overload ( P < 0 .05 ) . Different patterns of the regional dysfunction were found among the different RV segments . No correlation was found between RVSP and global or segmental EF in patients with pressure overload . Conclusions RT‐3DE could be used to assess global and segmental RV systolic function in patients with pressure and volume overload .