80 and further did Spearman correlation analysis and Logistic regression analysis to all patients for the prognosis and its factors(age,gender,SIRS,infection,blood sodium/potassium/free calcium,CRP,PLT and PCIS value as well as blood sugar level).Results the SIRS rate of the subject patients in PICU was 48.3%.SIRS group featured higher MODS rate,lower PCIS value and worse prognosis than those in Non-SIRS group(Pa80(P

Objective: To establish a three dimensional finite element model of normal clavicle and calculate the stress and strain distribution on the clavicle under the axial load,so as to provide a numerical model for analysis of biomechanical behaviors. Methods: The right clavicle of a healthy normal male was scanned by CT and serial sections were obtained. Then the CT images were fed into the Simpleware and ANSYS software to create the model through a serial steps including meshing, assigning the material attribution,restricting the freedom and simulating axial loading. The result of stress distribution and response of the model was obtained. Results: The established model had 62 182 nodes and 40 878 tetrahedral units. The stress mainly concentrated within the middle 1/3 part of the clavicle under axial loading,and the stress on the inferior surface was obviously higher than that on the superior surface. Conclusion: The stress distribution analysis explains the reason why the middle 1/3 region of clavicle is prone to fracture. The stress mainly focuses on the inferior surface and the bending movement leading to clavicle fracture is located on the coronal plane,indicating that placement of plate in the superior surface can effectively balance the bending movement and avoid fixation failure during internal fixation of middle segment clavicle fracture. In a word, finite element analysis can be used to effectively investigate the biomechanic characteristics of clavicle.

Objective: To explore the effect of psychotherapy in treating middle school students with IAD (internet addiction disorder). Methods: 23 cases of middle school students with IAD had been treated by cognitive therapy or behavior therapy. The IAD scale, SCL-90 scale and SDS scale were used to evaluate the effect before and after therapy. Results: After therapy, the total scores and most dimensions scores in IAD scale, SCL-90 scale and SDS scale decreased significantly than that before therapy. Conclusions: Psychotherapy especially cognitive therapy and behavior therapy is an effective in treating middle school students with IAD.

Chromosome Aberrations ; Combined Modality Therapy ; Humans ; Killer Cells, Natural ; pathology ; Lymphoma, T-Cell ; etiology ; genetics ; pathology ; therapy ; Nose Neoplasms ; etiology ; genetics ; pathology ; therapy ; Prognosis

Hepatectomy ; methods ; Humans ; Liver ; blood supply

Animals ; Female ; Gonads ; physiopathology ; Hypothermia ; chemically induced ; physiopathology ; Male ; Rats ; Rats, Wistar ; Sex Factors ; Soman ; adverse effects ; pharmacology

Diagnosis, Differential ; Humans ; RNA, Viral ; genetics ; Reverse Transcriptase Polymerase Chain Reaction ; SARS Virus ; genetics ; Sequence Analysis, DNA ; Severe Acute Respiratory Syndrome ; diagnosis ; virology

Melanin is formed by oxidative polymerization of phenolic compounds,basically different kinds of melanin come from different organisms.DOPA melanin and DHN melanin have same physical and chemical characters although they have different biosynthetic pathway.DHN melanin is common in plant fungi and plays an important role on infection.The melanin accumulates in the fungal cell walls and prevents organic and inorganic molecules penetrating out,that insures appressorium's pressure and infection ability.This paper has reviewed the kinds and characters,especially discussed the role of melanin during pathogen infection based on our some research.

Adult ; Hand Injuries ; surgery ; Humans ; Male ; Occupational Diseases ; surgery ; Paint

OBJECTIVETo systematically evaluate prostate health index (PHI) in predicting the results of prostate biopsy in the diagnosis of prostate cancer.

METHODSWe retrieved the literature relevant to the value of PHI in predicting prostate cancer at prostate biopsy published from the inception to February 2014 in the databanks of PubMed (1966 - 2014), CNKI (1982 - 2014), VIP (1989 - 2014), and Cochrane Library (1999 - 2014). According to the inclusion and exclusion criteria and retrieval strategies, we extracted the data, evaluated the quality of the included literature, and performed meta-analysis using the Meta-Disc 1.4 software.

RESULTSTotally, 64 articles were identified, of which 52 were excluded and 12 included with 1 430 cases of prostate cancer and 2 159 normal or BPH controls. There was heterogeneity among the included studies. Based on the random effect model, in predicting the results of prostate biopsy in the diagnosis of prostate cancer, serum PHI exhibited a pooled sensitivity of 55.1% (95% CI: 0.525 - 0.577), a pooled specificity of 71.5% (95% CI: 0.695 - 0.734), a positive likelihood ratio (P-LR) of 2.379 (95% CI: 1.922 - 2.943), a negative likelihood ratio (N-LR) of 0.515 (95% CI: 0.428 - 0.619), a diagnosis odds ratio (DOR) of 5.268 (95% CI: 3.870 - 7.170), a summary receiver operating characteristic curve--area under the curve (SROC AUC) of 0.7578, and a Q * index of 0.6999.

CONCLUSIONSerum PHI plays a role of auxiliary diagnosis in detecting prostate cancer and can be used in the prediction of the results of prostate biopsy.

Aged ; Biopsy, Needle ; Humans ; Male ; Middle Aged ; Prostate ; pathology ; Prostatic Neoplasms ; diagnosis ; pathology