Child ; Guidelines as Topic ; Humans ; Rhinitis, Allergic, Perennial ; diagnosis ; therapy ; Rhinitis, Allergic, Seasonal ; diagnosis ; therapy

Humans ; Rhinitis ; classification

Chronic Disease ; Humans ; Rhinitis ; Sinusitis

Environment ; Humans ; Rhinitis, Allergic ; epidemiology

Chronic Disease ; Combined Modality Therapy ; Humans ; Research ; Sinusitis ; therapy

Child ; Humans ; Rhinitis, Allergic, Perennial ; diagnosis ; therapy

OBJECTIVE To observe the inhibition of the expression of HIF-1? and VEGF induced by LPS in primary human nasal epithelial cell (HNEC) by dexamethasone. METHODS Epithelial cells of nasal polyps (NP) and inferior turbinate (IT) were cultured without serum under stimulus of LPS 100 ng/ml, IL-1? 20 ng/ml, LPS 100 ng/ml +dexamethasone 13 ng/ml and IL-1? 20 ng/ml+ dexamethasone 13 ng/ml for 3h, 6h and 9h respectively. The expression of HIF-1?, VEGF protein and mRNA derived from epithelial cells was detected by immunocytochemistry and situ hybridization. RESULTS ①The expression of HIF-1? and VEGF increased under the stimulus of LPS and IL-1? with the increasing of time and concentration, especially under LPS 100 ng/ml for 6h (P

Adenoid cystic carcinoma(ACC) of the salivary gland constitutes approximately 21.9%-24.0% of all salivary gland malignant tumors,and is described as a tumor with indolent,but persistent and recurrent,growth and late onset of metastases,leading eventually to death.This review focuses on the advances in the studies of the diagnosis,treatment,and prognosis of ACC in the recent years.

Child ; Humans ; Rhinitis, Allergic ; Rhinitis, Allergic, Perennial

Anaphylaxis ; Humans ; Hypersensitivity ; Rhinitis ; classification ; Rhinitis, Allergic, Perennial ; Rhinitis, Allergic, Seasonal ; Terminology as Topic