Administration, Oral ; Anti-Inflammatory Agents, Non-Steroidal ; adverse effects ; therapeutic use ; Aspirin ; adverse effects ; therapeutic use ; Brain Edema ; chemically induced ; Child ; Coma ; chemically induced ; Female ; Humans ; Liver ; drug effects ; pathology ; physiopathology ; Reye Syndrome ; chemically induced ; Treatment Outcome

Adolescent ; Adult ; Dimethylformamide ; adverse effects ; Female ; Humans ; Kidney ; drug effects ; physiopathology ; Lipid Metabolism ; drug effects ; Liver ; drug effects ; physiopathology ; Male ; Middle Aged ; Occupational Exposure ; adverse effects ; Young Adult

Adolescent ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Male ; Paraquat ; poisoning

Adult ; Aged ; Atrial Fibrillation ; etiology ; prevention & control ; Bronchoalveolar Lavage ; adverse effects ; Humans ; Male ; Middle Aged

Adenocarcinoma ; metabolism ; pathology ; Adult ; Aged ; Carcinoma, Non-Small-Cell Lung ; metabolism ; pathology ; Carcinoma, Squamous Cell ; metabolism ; pathology ; Female ; Humans ; Immunohistochemistry ; Lung ; chemistry ; pathology ; Lung Neoplasms ; metabolism ; pathology ; Male ; Middle Aged ; Oxidoreductases ; metabolism ; Sex Factors ; Smoking ; Tumor Suppressor Proteins ; metabolism ; WW Domain-Containing Oxidoreductase

Salsola collina is widely distributed in droughty and semi-droughty area, which is used as a kind of folk remedy in traditional Chinese medicine for treatment of hypertension. The study is on the chemical constituents of this herb from its aerial parts to obtain its active constituents. Dried and crushed aerial parts of this herb were extracted three times with 95% EtOH at reflux. The ethanol extracts were combined and concentrated under reduced pressure at 70 ℃ to yield residue, which was suspended in water and successively partitioned with light petroleum, chloroform and n-butanol. The chloroform and n-butanol fractions were treated by various chromatographic techniques, such as silica gel, C18 reversed-phase silica gel and macroporous resin column chromatography. Compounds were elucidated by their physicochemical properties and spectroscopic analysis. In the course of our study on searching biological active components from this herb, a new alkaloid together with three known alkaloids were isolated and identified as N-transferuloyl-3-methyldopamine (1), 3-[4-(β-D-glucopyranosyloxy)-3- methoxyphenyl]-N-[2-(4-hydroxyl-3-methoxyphenyl)ethyl]-2-propenamide (2), salsoline A (3), salsoline B (4). Compound 4 is a new compound and named as salsoline B, while compound 2 was obtained in Salsola collina for the first time.

Objective To evaluate the diagnostic evaluation of isotropic scanning and Lung Care soft- ware in solitary pulmonary nodules,and to improve the diagnostic accuracy.Methods 52 patients suffered from SPN were included in our study.Two experts in CT analyzed the films.First,they read the axial images and made diagnosis.Then isotropic scanning and lung care software approaches were used on 16 spiral CT and another analysis were made again.The results were compared with pathological diagnosis respectively. Results Spiculated sign,lobulated sign,vessel convergence were found more on isotropic scanning approach, that had significant difference with axial images analysis(P

Objective To study the relationship between renal morphology and renal function,and to assess the value of CT as a criterion to grade renal function.Methods Enhancement CT were performed in 89 patients with no local renal disease whose split renal glomerular filtration rates(GFR)were measured by renal dynamic imaging with ~(99)Tc~m-DTPA.The 178 kidneys were divided into normal renal function,mild and severe renal impairment groups according to renal function.Differences between three groups respect to the mean thickness of renal cortex and parenchyma were assessed by ANOVA.Using Pearson's correlation test,the correlation between the renal cortex,parenchyma thicknesses and renal GFR were examined.The value of CT in predicting renal function was assessed by using ROC analysis.Results The renal cortex thicknesses of normal renal function,mild and severe renal impairment groups were(5.9?1.1),(4.6? 1.1),and(3.3?1.0)mm respectively,and the renal parenchyma thicknesses were(26.3?4.2), (21.3?4.6),(16.2?4.6)mm.There were significant differences of renal cortex,parenchyma thicknesses between 3 groups(cortex F=54.78,P

Objective To discuss the relationship between thickness of RNFL and visual field, and its application in forensic identification. Methods Using the GDxVCC and Octopus automatic perimeter to check on 52 optic nerve lesion cases. The data is grouped according to valid value of visual field (Group1- severe injury group, Group2-minor injury group, Group3- slight and following slight injury group) , calculated for the averaged RNFL thickness, and analyzed by ANOVA. Meanwhile, the correlation between RNFL thickness and visual field indices(effective value of visual field, MD, MS, sLV) was analyzed with Pearson's correlation and described in scattered plot. Results Group 1 to 3 average RNFL thickness was 60.9036±9.53514μm, 53.6474±15.45306μm, 36.3±8.45695μm accordingly. Through ANOVA we can see that differences wer significant between every group. The valid value of visual field and MS were positively with the average RNFL thickness with a correlation of 0.543, 0.400, respectively(P<0.05). The MD and sLV were negatively correlated with the average RNFL thickness with correlation -0.450、-0.440, respectively(P<0.05). Linear relationship between the average RNFL thickness and effective value of visual field, MD, MS, sLV were Y=0.967X+19.508, Y=0.095X-10.858, Y=0.175X+9.187, Y=-0.205X+20.215accordingly. Nonlinear relationship between the average RNFL thickness and effective value of visual field, MD, MS, sLV were Y=-0.037X2+5.208X-93.795, Y=0.010X2-1.325X+50.111, Y=-0.008X2+1.103X-15.606, Y=0.004X2 -0.520X+22.232. Conclusion RNFL thickness measurement is expected to be an objective assessment in visual field, a new morphological methods.

Objective To investigate the effect of Huangqi four Decoction in treating gestational diabetes mellitus (GDM) and its effect on the levels of Mg2+,CRP,adiponectin and complications.Methods In our hospital from August 2015 to January 2017 were 130 cases of gestational diabetes patients as the research object,the patients were randomly divided into observation group and control group with 65 cases in each group,the control group was given conventional treatment,patients in the observation group in the conventional treatment based on the use of Astragalus four gentleman decoction,observe two groups of patients before and after fasting blood glucose (FPG),2h postprandial blood glucose (2 hPG),glycosylated hemoglobin (HbA1c),and Mg2+,CRP and serum adiponectin levels and occurrence of complications after treatment and the curative effect.Results After treatment,the observation group FPG[(5.30±0.3)mmol/L],2 hPG[(5.36±0.27)mmol/L],HbA1c[(5.58±1.29%)]levels were lower than those of control group[(5.68±0.38)mmol/L,(6.01±0.33)mmol/L,(6.86±1.35)%],the two groups was statistically significant (P<0.05).In the observation group,Mg2+ [(1.25±0.36)mmol/L] and adiponectin[(35.24±5.18)μg/L] levels were higher than those of the control group [(0.91±0.30)mmol/L and (30.76±4.85)μg/L],while CRP [(1.59±0.35)mg/L] was lower than control group[(2.21±0.46)mg/L],the difference was statistically significance(P<0.05);observation group of adverse reactions in patients with abdominal pain,abdominal distension,the incidence of hypoglycemia (9.23%) than in the control group (38.46%),the two groups was statistically significant (P<0.05);the patients in observation group after treatment The total effective rate (96.92%) was higher than that of the control group (n=87.69%),and the difference between the two groups was statistically significant (P<0.05).Conclusion Astragalus four Decoction in the treatment of gestational diabetes can effectively reduce blood glucose,improve Mg2+,CRP,adiponectin and other related indicators,reduce the incidence of complications,the effect is significant,worthy of clinical application.