1.Effect of sodium ozagrel combined with cobamamide and pancreatic kininogenase on diabetic peripheral neuropathy
Clinical Medicine of China 2011;27(6):575-577
Objective To observe curative effect of sodium ozagrel combined with cobamamide and pancreatic kininogenase in patients with diabetic peripheral neuropathy (DNP). Methods Seventy-two diabetes patients with DNP in our hospital from September, 2008 to September, 2010 were randomly divided into observation group and control group. All patients were treated with cobamamide by intramuscular injection and pancreatic kininogenase taken orally. In the observation group sodium ozagrel injection were added to the treatment used in the control group. Results After one course of treatment, the total effective rate in the observation group was 91. 7% (31/36),which was better than the control group (63. 9% ,23/36) (x =7. 6, P<0. 05). Motor nerve conduction velocity of median nerve before and after treatment was (42.9 ± 1.9)m/s and(45. 9 ± 3. 0) m/s in the observation group, and (42. 2 ± 1. 7) m/s and (43. 1 ± 2. 1) m/s in the control group. Motor nerve conduction velocity of peroneal nerve before and after treatment was (34. 9 ± 3. 9) m/s and (46. 1 ±3.0)m/s in the observation group, ,and (35. 6 ±3.4)m/s and(36. 8 ±2. 5)m/s in the control group;Sensory nerve conduction velocity of median nerve was (41.2 ±3.2) m/s and (48. 5 ±4.0) m/s in the observation group,and (41. 5 ±3. 8)m/s and(42.4 ±3. 6) m/s in the control group, sensory nerve conduction velocity of peroneal nerve was(35.4 ±3. 4) m/s and(44. 8 ± 3. 2) m/s in the observation group, and (35. 9 ± 4.4) m/s and(37. 6 ± 3. 3) m/s in the control group. The difference of nerve conduction velocity before and after treatment in the observation group reached the statistical significance(P<0. 05), whereas not significant in the control group (P > 0. 05). After treatment, the nerve conduction velocity in the observation group significant better than those in the control group (P < 0. 05). Conclusion The treatments of sodium ozagrel combined with cobamamide and pancreatic kininogenase in diabetic peripheral neuropathy is safe and effective.
2.The method of communicative English testing in CET
Journal of Chongqing Medical University 2000;25(z1):121-122
The method of Communicative English Testing (MCET) is one of the moder, scientific language testing methods suitable for the principle of quality education. In this article, the writer introduces the theoretical basis, testing content and the application in CET, including the setting and scoring principles by examples on MCET.
3.Applications of the zebrafish in the studies of developmental pediatrics
International Journal of Pediatrics 2011;38(2):178-180
Zebrafish as a new animal model is gradually being recognized. Easy fed, growing rapidly,transparent embryo, strong reproduction, especially similar with human in gene structure, body regulation patterns, and the development of organs and disease, all those characteristics make zebrafish significant in development of vertebrate animal and human disease. This review focuses on discussing the applications of the major organs of zebrafish in the studies of developmental pediatrics.
4.Application of all-inclusive nursing for patients with orthopedic trauma
Chinese Journal of Practical Nursing 2009;25(27):6-8
Objective To discuss the influence of all- inclusive nursing for patients with orthopedic trauma on the aspects of their body and mind. Methods According to the related reference, made out allinclusive nursing ideas, and then used in 100 patients with orthopedic trauma (intervention group), routine rehabilitation was used in the control group (100 cases with orthopedic trauma). Compared the somatopsychic codition and the rehabilitation between the two groups. Results The 6 indexes of rehabilitation in the intervention group were significant better than those of in the control group. Somatopsychic condition in the intervention group was satisfactory. Conclusions All-inclusive nursing should be promoted in chnic by its merits.
5.Research in intermittent urethral catheterization combined with audio frequency electrotherapy and microwave therapy in the treatment of patients with spastic bladder after spinal cord injury
Chinese Journal of Practical Nursing 2008;24(24):8-9
Objective To discuss methods for recovery of bladder function and autonomous urination for patients with spastic bladder after spinal cord injury. Methods Patients in the experimental group(30 cases)received intermittent urethral catheterization 6 times per day,audio frequency electrotherapy and microwave therapy 2 times per day.The control group(30 cases)adopted routine urethral catheterization.The recovery of bladder function of the two groups Was observed.Results The rate of autonomous urination in the experimental group was higher than that of the control group(P<0.01).Increase of bladder capacity and decrease of remnant urine volume in the experimental group was better than that of the control group(P<0.05).Conclusions Intermittent urethral catheterization combined with audio frequency electrotherapy and microwave therapy could effectively promote the recovery of bladder function for patients with spastic bladder after spinal cord injury.
6.The importance to rectify the microecological disturbance of vaginain gestational period in treating colpitis
Chinese Journal of Primary Medicine and Pharmacy 2008;15(7):1124-1126
Objective. To detect vaginal mieroecosystem and discuss the importance to rectify the microeco- logical disturbance of vagina in gestational period in treating colpitis. Methods 250 prenatal care women in our hos- pital were selected as samples. We coUeeted vaginal secretion, made mieroeeological evaluation based on Gram stained smear, and detected leukocyte esterase, concentration of hydrogen dioxide and sialie acid-anhydride esterase. Different treatments were used randomly to these with vaginal ecological disturbance to investigate the cure rate of microeco- logical disturbance of vagina and colpitis,and the recrudescence rate of colpitis. Results 166 of the 250 women had microeeological disturbance of vagina,in the 166 women, 110 had semplice mieroecological disturbance of vagina and 56 had colpitis. In the group with vaginal ecological disturbance, the rate of well-balanced vaginal ecology was in- creased obviously and the rate of colpitiz was low. The difference was of statistical significance. In the group with col- pitis, after equilibrium treatment, the cure rate of colpitis in the study group was much higer than the control group after five-days' treatment,but no significant difference after ten-days' treatment. The recrudescence rate of colpitis was much lower in the study group than that in the control group. Conclusion Rectify the microecological distur- bance of vagina will shorten the period of treatment and reduce the recrudescence rate of colpitis.
7.Experimental study on the effect of yam polysaccharide for diabetic mice
Chinese Journal of Primary Medicine and Pharmacy 2011;18(5):604-605
Objective To explore the effect of yam polysaccharide for the diabetic mice. Methods Ninty mice were randomly divided into three groups ,yam polysaccharide group(n = 30), glibenclamide group (n = 30) and control group(n = 30). Mice were Intraperitoneal injection of alloxan (200mg/kg) to establish diabetic model. Yam polysaccharide group was administered yam polysaccharide for 12d. Results Yam polysaccharide significantly decreased the blood sugar of the diabetic mice. There were not significantly different in two groups (P > 0.05).Conclusion Yam polysaccharide had obvious role in decreasing blood glucose.
8.Analysis of the risk factors of shivering after intraspinal anesthesia
Chinese Journal of Primary Medicine and Pharmacy 2016;23(8):1178-1181
Objective To explore the risk factors of shivering after intraspinal anesthesia.Methods 640 anesthesia recovery patients after intraspinal anesthesia from February 2011 to May 2015 were selected as the research subjects.According to whether patients appeared shivering,they were divided into research group and control group.The research group had 328 cases of appearing shivering,the control group had 312 cases without shivering. Basic clinical data of patients,operation time and blood loss,tympanic membrane temperature,anesthesia,anesthesia blocks plane indicators were compared to explore the risk factors of shivering after intraspinal anesthesia.Results This study included 640 cases,including 328 cases with chills reaction,the incidence rate was 51.25%.Single factor results showed that the low age,male,central cooler,surgery for a long time,the bleeding of more lumbar hemp,choice of anesthetic methods and anesthetic plane above T8 indicators, there were close relationship with shivering after intraspinal anesthesia,the differences between the two groups were statistically significant (χ2 =40.661,17.208, 32.369,32.931,36.624,14.844,26.84,all P<0.05).Multivariable logistic regression analysis results showed that age,gender,core body temperature,operation time,blood loss,spinal canal anesthesia methods and indexes of anes-thetic plane were important risk factors of chills reaction after anesthesia in patients with spinal canal anesthesia (OR=1.843,1.925,2.183,0.548,0.497,0.529,0.743,all P<0.05).Conclusion Male,younger age,operation for a long time,big intraoperative blood loss,tympanic membrane temperature low mode selection subarachnoid block anesthesia,and the anesthesia plane factor are the main risk factors of spinal canal anesthesia patients to appear chills response,the above factors are needed for close monitoring of patients with intraspinal anesthesia in the preoperative period.
9.Using Ig/TCR gene rearrangements to monitor minimal residual disease in pediatric lymphoma
Journal of Leukemia & Lymphoma 2010;19(11):695-698
Detection of minimal residual disease (MRD) exactly for lymphoma is important for estimating prognosis, assessing response, monitoring relapse and instructing treatment. Immunoglobulin (Ig)/T-cell receptor (TCR) gene rearrangements can be used as special tumorous markers for MRD testing by PCR.BIOMED-2 strategy is a method about multiplex PCR reaction designed by European Collaborative Organization. Monitoring MRD can be completed by real-time quantitative PCR. In this paper, the principle and research progress related to the application of IG/TCR in MRD detection are mainly reviewed for lymphoma in children.
10.Discussion on refresher training in the department of obstetrics
Chinese Journal of Medical Education Research 2013;(12):1245-1247
Physicians receiving refresher training are fully involved in clinical work in depart-ment of obstetrics in 3A hospital. The quality of training is related with the improvement of their pro-fessional ability and medical treatment safety of the hospital. To improve the teaching quality for ob-stetrics refresher doctors, several methods were implemented including paying more attention to the humanistic quality training, taking care of their physical and mental health,strengthening their basic rationale and basic skill, upgrading their obstetric knowledge and improving their ability to deal with an emergency condition. All these efforts have achieved good results in obstetric teaching.