1.Improvement Effect of Eucalyptol Enteric Soft Capsule on Lipopolysaccharide-induced Acute Lung Injury in Mice
China Pharmacy 2017;28(19):2655-2658
OBJECTIVE:To investigate the improvement effect of Eucalyptol enteric soft capsule on mice with lipopolysaccha-ride(LPS)-induced acute lung injury(ALI). METHODS:60 mice were randomly divided into blank control group,model control group,Eucalyptol enteric soft capsule low-dose,medium-dose,high-dose groups(100,300,900 mg/kg),12 in each group. Mice in administration groups were intragastrically given relevant medicines,mice in blank control group and model control group were intragastrically given equal volume of normal saline(0.1 mL/10 g). After 2 h of administration,except for the blank control group, ALI was induced in other groups by atomized LPS. After 6 h of modeling,the mice were sacrificed,alveolar lavage fluid(BALF) and lung tissue were taken. Morphological changes of lung tissue were observed under microscope;number of total cells,neutro-phils in BALF were calculated by blood cell count plate and staining by wright-giemsa respectively. Total protein concentration in BALF supernatant was detected by BCA method;TNF-α,IL-6 contents in BALF supernatant were determined by enzyme-linked immunosorbent assay. RESULTS:Compared with blank control group,lung tissue of mice in model control group showed obvious pathological damage and severe pulmonary edema;number of total cells,neutrophils in BALF,total protein concentration and TNF-α,IL-6 contents in BALF supernatant were significantly increased(P<0.01). Compared with model control group,pathologi-cal damage in lung tissue of mice was obviously improved in Eucalyptol enteric soft capsule high-dose group,number of total cells,neutrophils in BALF,total protein concentration and TNF-α,IL-6 contents in BALF supernatant were significantly decreased (P<0.05);and there were no significant differences in other groups (P>0.05). CONCLUSIONS:High-dose Eucalyptol enteric soft capsule can obviously improve LPS-induced ALI of mice.
2.The rate of lower reproductive tract infection of pregnant and its effect on pregnancy outcome
Danhua SUN ; Xuan LI ; Cuifang YANG
Clinical Medicine of China 2014;30(4):347-349
Objective To investigate the rate of lower reproductive tract infection during pregnancy and the its impact on pregnancy outcome.Methods Five hundred and twenty pregnant women were enrolled in the study who were hospitalized for delivery from Jan.2010 to Jan.2012 at Hebei Port Group Company Limited Harbor hospital.All pregnant women were performed the bacteria detection in vagina before delivery,including candida albicans,bacterial vaginosis,trichomonas,mycoplasma,trachomatis and Neisseria gonorrhoeae,group B hemolytic streptococci GBS.The pregnant outcomes were followed.According to the results of bacteria detection,107 patients (20.58%) were with varying degrees of vaginitis and they were served as positive group.Other 403 patients were served as negative group.Results (1) Of 107 vaginitis women,48 cases (44.86%) were infected with candida albicans,and 22 cases (20.56%) were with bacterial vaginosis.The infection by mycoplasma,chlamydia,group B streptococcal infections were majority,while the trichomonas vaginalis,Neisseria gonorrhoeae infection were minority.(2) Compared with the negative group,incidence of premature rupture of membranes,preterm birth,puerperal infection and fetal distress in positive group were higher and the differences were significant(15.89% vs.5.08%,12.15% vs.3.15%,8.41% vs.1.94%,5.61% vs.1.21% ; x2 =14.642,14.498,11.264,7.934; P < 0.01).Conclusion The incidence of genital tract infection is higher during the pregnancy.Bacteria infection detection should be performed and treated as early as possible in order to reduce the occurrence of adverse pregnancy outcome.
3.Effects of scalp acupuncture on acute cerebral ischemia-reperfusion injury in rats.
Hongxing ZHANG ; Qiong WANG ; Li ZHOU ; Lingguang LIU ; Xuan YANG ; Min YANG ; Yinni LIU ; Xuan LI
Journal of Integrative Medicine 2009;7(8):769-74
To explore the mechanisms of scalp acupuncture in treating cerebral ischemia in rats.
4.The influence on smoking and drinking status of officers and soldiers after health management
Zhenzhen WANG ; Xianrong LUO ; Xuan YANG ; Jun YANG ; Shaen LI
Chinese Journal of Behavioral Medicine and Brain Science 2014;23(3):261-263
Objective To investigate the influence of smoking,drinking cognition and behavior among the officers and soldiers in South China War Zone after health management,and to explore the establishrent of appropriate health management model for the army.Methods Harmfulness cognition,rate,quantity,types of drinking and smoking were investigated and analyzed before and after health management among 1 102 officers and soldiers in South China War Zone by providing a set of health education,psychological counseling service,disease and lifestyle intervention of health management as a whole.Results The harmfulness cognition rate of smoking and drinking raised from 95.6% and 94.1% to 98.7% and 97.8%,the smoking and drinking rate dropped from 64.7% and 72.6% to 37.2% and 61.4% after health management.The x2 values were 18,18.9,153,20.8,and had significant difference (P<0.001).The rate of occasional smoking,a small amount of smoking,often smoking dropped from 28.3%,25.8%,45.9% to 18.5%,12.2%,31.5% as well as the rate of occasional drinking,a small amount of drinking,often drinking has dropped from 56.6%,32.3%,11.1% to 49.8%,23.4%,4.1%.The x2 values were 26.8,62.1,31,9.61,8.06,19.4,and had significant difference (all P<0.01).Conclusion The health management improves the harmfulness cognition of smoking and drinking,and decreases the rate and quantity of smoking and driking.It has a positive effect on improving the heahh literacy and developing health way of life in officers and soldiers.
5.Congenital tracheal diverticulum in a case.
Yang WANG ; Li-li WANG ; Gui-hua XUAN
Chinese Journal of Pediatrics 2010;48(5):397-398
6.Changes in bone mineral density and bone turnover in postmenopausal osteoporotic patients treated with salmon calcitonin nasal spray
Lige SONG ; Xiangjun MENG ; Yingli XUAN ; Hao YANG ; Hong LI ; Miao XUAN ; Xiuzhen ZHANG
Chinese Journal of Endocrinology and Metabolism 2011;27(2):106-109
Objective To study the changes of bone mineral density(BMD)and bone turnover in postmenopausal osteoporotic patients treated with salmon calcitonin nasal spray. Methods Sixty-seven postmenopausal osteoporotic patients were enrolled in our trial. All of them received calcium and vitamin D; 37patients were treated with salmon calcitonin nasal spray for 12 months and the other 30 patients received calcium and vitamin D only. Dual-energy X-ray absorptiometry(DEXA)and measurements of a series of bone turnover indices were performed before and after medication for 6 and 12 months. Results After treatment with salmon calcitonin nasal spray for6 months, BMD in lumbar spine 2-4 increased but no change occurred in femoral neck. However, after treatment for 12 months, BMD in both lumbar spine 2-4 and femoral neck increased. In the control group, BMD in lumbar spine 2-4 decreased after treatment for 6 and 12 months, but BMD in femoral neck decreased only after 12months. Comparing with the control group, after treatment with salmon calcitonin nasal spray, BMD in lumbar spine 2-4 and femoral neck were increased obviously. The level of TRACP-5b and NTX/Cr decreased after treatment with salmon calcitonin nasal spray for6 months and 12 months, while BALP increased only after treatment for 12 months. In the control group, BALP decreased after treatment for 12 months. The level of 25-(OH)vitamin D increased after treatment for 6 months and 12 months in both groups. Conclusions Long-term treatment with salmon calcitonin nasal spray prevents bone loss and may increase bone mass.
7.Research progress of Chinese medicine treatment for chest contusion
Haiwen PAN ; Haiyun YANG ; Tianhang XUAN ; Chongzhi ZHAO ; Qingbin LI
International Journal of Traditional Chinese Medicine 2016;38(9):859-861
Chest contusion is the soft-tissue injury disorders that the external violence directly destroys the chest wall and the soft tissues, causing chest pain, fullness, and symptoms aggravate when the chest moves. Chinese medicine showed many treatments with clinical efficacy. Therefore, Chinese medicine has been widely used in clinics. This paper was to review the research progress of Chinese medicine treatment for chest contusion.
8.Study on Determination of Main Components in Honey by Near-infrared Spectroscopy
Lin QIU ; Ying LIU ; Yuanyuan ZHANG ; Wanyi LI ; Xuan YANG
World Science and Technology-Modernization of Traditional Chinese Medicine 2015;(9):1949-1952
This study was aimed to establish a fast determination method of main components in honey. Honey samples from difference production bases were used as study objects. Transmission and reflection spectra of different honey samples were collected with the Fourier transform near infrared spectrometer. The main components in honey (moisture content, fructose content, glucose content and reducing sugar content) were detected by the near infrared quantitative analysis technique. The near infrared quantitative analysis models of moisture content, fructose content, glucose content and reducing sugar content in honey were established by the partial least squares (PLS). The results showed that the correlation coefficient (r) of the moisture content, fructose content, glucose content and reducing sugar content in honey were 0.997 25, 0.973 90, 0.927 94 and 0.952 68, respectively. The root mean square error of prediction (RMSEP) were 0.165 (%), 0.564 (%), 1.300 (%) and 1.270 (%), respectively. It was concluded that determination of main components in honey by the near-infrared spectroscopy technology was a fast and nondestructive determination method with high accuracy, which can be used in the quantitative detection of main components in honey.
9.Computer-aided prosthetic socket manufacturing system based on an advanced manufacture technology
Peng YANG ; Lingling CHEN ; Song LI ; Bokai XUAN
Chinese Journal of Tissue Engineering Research 2009;13(22):4391-4395
OBJECTIVE:To overcome the shortcoming of manual method,computer-aided manufacturing (CAM) system of prosthetic socket is applied to improve socket's quality and processing efficiency,which also reduces the demand of operator's knowledge and experience.METHODS:Prosthetic socket CAM system was discussed based on an advanced manufacture technology,and the hardware and software were designed.The advanced manufacture platform was composed of an industrial personal computer (IPC),a motion control card,four sets of Panasonic digital AC servo control system,four lead screw guides,two spindle motor of milling cutter,a transducer,two switching power supply,limit switch and proximity switch.The software of prosthetic socket CAM system mainly included three function modules:parameter setting,machine testing and beginning processing.Through adjusting command pulse's input and driver's coefficient,the motor worked at different speeds.RESULTS:The result of experiment demonstrated that maximum rotational speed restriction was applied to protect the motor,and the motor could work very smoothly without vibration in very low speed.It was suitable for manufacture prosthetic sockets,and could manufacture the high quality prosthetic socket to satisfy the requirements of amputee.CONCLUSION:Prosthetic socket CAM system based on the advanced manufacture platform can overcome the shortcoming of traditional manual method,ensure product quality,and reduce the cost.The protracted experience of certified prosthetist was incorporated into the design program to reduce the demand of manipulator's knowledge and experience,increase the one-time success rate of manufacture prosthetic sockets,and improve the quality uncertainty of sockets.It can change the backward production mode of designing,measuring,taking model,and modifying model which depends on handwork.
10.Creation of a special medical service mechanism for large international sport events
Yang LI ; Shiying XUAN ; Tongqin HAN ; Qian GAO
Chinese Journal of Hospital Administration 2009;25(6):379-381
For medical service provision for the Olympic Games, a special medical service mechanism for important international sport events eventually took shape, based on task analysis and medical services provided in test games for two years including 2006 and 2007 Qingdao Sailing Regatta. This mechanism features the following: First, "7-Special" sport event medical practice - Medical zones, medical teams, service flows, service signs, medical papers, and drug management, all exclusively earmarked for the event; Second, medical services up to international standard; Third, special flows for medical rescue; Fourth, Special system for information reporting. Thanks to this special mechanism, the hospital provided its medical assurance for the Olympic Games successfully, and upgraded its routine medical services as a result.