1.Bilingual education in the teaching of cardiothoracic surgery practice and exploration
Chun HUANG ; Xiaoyong XIANG ; Bin WANG
Chinese Journal of Medical Education Research 2011;10(3):325-327
Bilingual education is an imporant teaching reform in universities. In recent years, cardiothoracic department has enacted the practice and exploration for bilingual teaching of cardiothoracic surgery. By creating high-quality teaching team, improving teaching methods and quality, creating bilingual learning environment, we have achieved satisfactory teaching effect.
2.Postoperative new onset arrhythmias after video-assisted thoracoscopic surgery compared with traditional open lung lobectomy : a prospective cohort study
Xiaowen WANG ; Chun HUANG ; Mingjian GE ; Bin WANG ; Xiaoyong XIANG
Chinese Journal of Thoracic and Cardiovascular Surgery 2013;(1):4-7
Objective Arrhythmias are one of the main causes of postoperative morbidity after thoracic surgery.The aim of this study was to evaluate whether video-assisted thoracoscopic surgery decreases the risk of postoperative arrhythmias compared with traditional open lung lobectomy.Methods 138 consecutive patients were enrolled from January 2011 to February 2012,after five age and risk factors matched,68 patients undergoing video-assisted thoracic surgery and 70 patients undergoing traditional open lung lobectomy were eligible for analysis.The rhythm was documented preoperatively and postoperatively with standard electrocardiogram (ECG) recording and ECG monitoring.All patients followed 3 months after hospital admission.Results There was a 17.6% incidence (12/68) of postoperative new-onset arrhythmias undergoing video-assisted thoracic surgery and 18.6% of patients (13/70) undergoing thoracotomy,but the difference was not statistically significant.In both groups,atrial fibrillation was the most common arrhythmia (60%).There was no significant difference in the other morbidity (P >0.05) and mortality rate(P =0.57,1.5% vs 2.9%) between the two groups.Conclusion New-onset arrhythmias,most frequently atrial fibrillation,are common after lung lobectomy.Regardless of surgical approach,postoperative arrhythmias after lobectomy occurred with equal frequency.New insights in the pathophysiology of postoperative thoracic arrhythmias and advances in prevention and therapy are need future study.
3.Effect of ligustrazine on expression of RhoA mRNA, ROCK-II protein in the lung and airway inflammation of allergic asthma model mice.
Yun-chun LUO ; Qiang-wei XIANG ; Qiang WANG
Chinese Journal of Pediatrics 2008;46(11):868-869
Animals
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Asthma
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drug therapy
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metabolism
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Inflammation
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Lung
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drug effects
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metabolism
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pathology
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Male
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Mice
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Mice, Inbred BALB C
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Phytotherapy
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Pyrazines
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pharmacology
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therapeutic use
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RNA, Messenger
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metabolism
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rho GTP-Binding Proteins
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metabolism
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rho-Associated Kinases
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metabolism
4.Therapeutic Effect of High Frequency Oscillatory Ventilation on Premature Infants with Respiratory Distress Syndrome
yan, WANG ; xiang-yong, KONG ; zhi-chun, FENG
Journal of Applied Clinical Pediatrics 2006;0(14):-
Objective To evaluate the effect of the high frequency oscillatory ventilation(HFOV) on the treatment of premature neonates with respiratory distress syndrome(RDS).Methods Seventy premature infants with RDS were randomly grouped as HFOV group(n=33) and conventional mandatory ventilation group(CMV group,n=37),based on their fetal age,weight,age,and their clinical condition from Jan.to Sep.in 2009.The blood gas analysis was detected and compared between the 2 groups.Results In HFOV group,the inhaled oxygen concentration,pa(CO2) decreased after treatment for 6 h,which were significantly lower than those at the beginning of the therapy(Pa
5.Design of an implantable system for the extraction, transmission and control of the cranial neural electric signals in brain computer interface
Xiang XIE ; Guolin LI ; Chun ZHANG ; Zhihua WANG
Chinese Journal of Tissue Engineering Research 2005;9(4):250-253
AIM:With the development of microelectronics and the microsurgery,it becomes possible to directly extract all kinds of information from the brains of organisms.How to establish a communicative pathway that does not dependent on human brain and human tissues between human brain and computer?Hence,we explored a design project of an implantable system that could be reasonably applied in the extraction,transmission and control of the cranial neural electric signals in brain computer interface(BCI). METHODS:To bring out a design project of an implantable electric system for the extraction,transmission and control of the cranial neural electric signals through the application of the latest microelectronic techniques into the domain of the extraction of brain electric signal and to discuss in detail the key technique,difficulty and possible solutions involved in the projects. CONCLUSION:The proposed project can collect cranial neural electric signals from different depth within 16× 16 with the data precision of 12 bit,which is a closed loop control system.
6.Two special cerebral hyponatremia.
Xiang-zhen NAN ; Yong-qing WANG ; Chun-xue YAN
Chinese Journal of Pediatrics 2003;41(9):715-717
7.Extraventricular neurocytoma of spinal cord: report of a case.
Chun-nian WANG ; Xiang-lei HE ; Zhao-xia XIA
Chinese Journal of Pathology 2012;41(10):702-703
Antigens, Nuclear
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metabolism
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Cordotomy
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methods
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Diagnosis, Differential
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Ependymoma
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metabolism
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pathology
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Follow-Up Studies
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Humans
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Male
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Middle Aged
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Nerve Tissue Proteins
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metabolism
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Neurocytoma
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metabolism
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pathology
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surgery
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Oligodendroglioma
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S100 Proteins
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metabolism
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Spinal Cord Neoplasms
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metabolism
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pathology
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surgery
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Synaptophysin
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metabolism
8.Clear cell papillary cystadenoma of left mesosalpinx associated with von Hippel-Lindau disease: report of a case.
Xiang-lei HE ; Chun-nian WANG ; Jian-min ZHANG
Chinese Journal of Pathology 2009;38(5):349-350
Adenocarcinoma, Clear Cell
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complications
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metabolism
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pathology
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surgery
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Adenoma
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pathology
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Adnexal Diseases
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pathology
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Adult
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Carcinoma, Renal Cell
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pathology
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secondary
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Cystadenoma, Papillary
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complications
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metabolism
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pathology
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surgery
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Diagnosis, Differential
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Fallopian Tube Neoplasms
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complications
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metabolism
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pathology
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surgery
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Female
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Follow-Up Studies
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Humans
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Keratin-7
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metabolism
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Kidney Neoplasms
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pathology
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secondary
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Mucin-1
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metabolism
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von Hippel-Lindau Disease
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complications
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metabolism
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pathology
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surgery
9.Filtration of the Best Medicine Concentration for Treatment of Open Soft Tissue Damage with the Improved Gudaofang
Chao XIANG ; Chun LI ; Jianhua RAO ; Zongsuai WANG ; Bifeng LI
Modern Hospital 2017;17(5):761-763
Objective To observe the clinical efficacy of improved Gudaofang at different concentrations for the treatment of soft tissue damage so as to determine its optimal concentration.Methods 150 patients with open soft tissue damage treated in our hospital from June 2014 to June 2016 were randomly divided into treatment Group A (n=40) and Group B (n=40), Group C(n=30)and control Group D (n=40).Group A, Group B and Group C were treated with 10%, 20%, 30% of improved Gudaofang respectively, while the control Group D was treated with 75% of alcohol.Its clinical efficacy was evaluated by tenderness score and swelling degree.Results Compared with post-treatment, different concentrations of improved Gudaofang significantly reduced the tenderness score and swelling degree (P<0.05).The total effective rate of Group A, Group B, Group C were 92.5%, 97.5% and 97.5%, respectively, were significantly better than the control Group D with 77.5% (P<0.05).Conclusion Different concentrations of improved Gudaofang has a certain clinical efficacy on treating open soft tissue damage.20% concentration of improved Gudaofang has the best cost-effective and is optimal drug concentration.
10.Comparison of two preparation methods applied in tanshinone II(A)-loaded PLGA nanoparticles.
Liang-Chun GAN ; Shi-Xiang HOU ; Yue-Qi BI ; Chang-Guang WANG ; Xin-Chun WANG ; Qi-Xiang CHEN
China Journal of Chinese Materia Medica 2007;32(7):578-581
OBJECTIVETo optimize formulation of tanshinone II(A)-loaded PLGA nanoparticles and compare the difference of two methods in preparation and quality of nanoparticles.
METHODThe two methods were nanoprecipitation method and emulsion-evaporation method. Single factor experiments and central composite design and response surface method were used to optimize the formulation of nanoparticles. The nanoparticles were characterized at size, morphology, entrapment efficiency, drug loading, drug recovery rate, crystallinity and drug release in vitro.
RESULTThe mean diameters were 225 nm and 183 nm, the entrapment efficiency were 95.49% and 87.99%, the drug loading were 2.03% and 0.16%, and the drug recovery rates were 38.42% and 17.59% respectively for nanoprecipitation method and emulsion-evaporation method.
CONCLUSIONNanoprecipitation method was better than emulsion-evaporation method for preparation of tanshinone II(A)-loaded PLGA nanoparticles.
Chemical Precipitation ; Crystallization ; Diterpenes, Abietane ; Emulsions ; Lactic Acid ; chemistry ; Nanoparticles ; chemistry ; Particle Size ; Phenanthrenes ; chemistry ; isolation & purification ; Plant Roots ; chemistry ; Plants, Medicinal ; chemistry ; Polyglycolic Acid ; chemistry ; Polymers ; chemistry ; Quality Control ; Salvia miltiorrhiza ; chemistry ; Technology, Pharmaceutical ; methods ; Volatilization