1.Imaging Technology and Imaging Findings in Pulmonary Aspergilloma
Lvjiao CHEN ; Jun XIA ; Yixiong CHEN
Journal of Practical Radiology 2001;0(05):-
Objective To investigate imaging technology and imaging finding in pulmonary aspergilloma.Methods Chest radiography,X-ray tomography and CT were perfovmed in 15 cases of pulmonary aspergilloma confirmed by pathology and the imaging results were compared with pathology.Results The accuracy was 60% for chest radiography,80% for chest radiography and X-ray tomography,93.3% for chest radiography and CT.“Air crescent sign” or “air ring sign” were shown in 9 patients.The fungus ball could move with the change of patient's body position in 5 cases. Conclusion A mobile intracavitary mass with “air crescent sign” or “air ring sign” is the imaging characteristics of pulmonary aspergilloma.
2.The research on the relationship between CD44,CYP2E1 genetic polymorphisms and esophageal cancer
Hong XIA ; Jun ZHOU ; Hongjun CHEN
China Oncology 2001;0(03):-
Background and purpose:Esophageal carcinoma is a common malignant tumor.Patients with esophageal carcinoma have a low survival rate.CD44 gene and CYP2E1 gene are related to invasion and metastasis of esophageal cancer,therefore we studied CD44 and CYP2E1 gene polymorphism in regard to its relationship with esophageal cancer. Methods :We analyzed CD44 and CYP2E1 genetic polymorphism in 45 cases with esophageal cancer and adjacent tissues by PCR technology. Results :CD44 protein was significantly over-expressed in tumor tissues than that in adjacent tissue(P
3.The influence of extract of schisandra chinensis and paeonia veitchii on the level of cytokines in serum of asthmatic rats
Xia CHEN ; Jun TANG ; Jing FENG
Chongqing Medicine 2013;(29):3486-3487,3490
Objective To investigate the influence of extract of schisandra chinensis and paeonia veitchii on level of cytokines in asthmatic rats .Methods SD rats were randomly divided into three groups :Chinese medicine-treated ,untreated asthma ,physiologi-cal saline control groups .The tracheal pathology and symptom of different groups were observed ,then cytokine expressions in ser-um were detected with enzyme-linked immunosorbent assay (ELISA ) .Results Chinese herb extract obviously improved tracheal pathology and airway symptoms .The levels of IL-4 ,IL-6、IL-13 in serum of Chinese medicine-treated and untreated asthma groups were significantly increased ,while the IFN-γ expression was reduced .But after treatment of Chinese herb extract ,compared with untreated asthma group the IFN-γexpression was significantly increased in Chinese medicine-treated group .Conclusion The effect of extract of schisandra chinensis and paeonia veitchii could reduce airway inflammation of asthma rats may by significantly in-creased IFN-γexpression .
4.Effect of Bifidobacterium spent culture supernatant on Pseudomonas aeruginosa adhering to intestinal epithelial cells
Jun CHEN ; Peiyuan XIA ; Guangxia XIAO
Journal of Third Military Medical University 2003;0(16):-
Objective To study the effect of Bifidobacterium spent culture supernatant (SCS) on adhesion of Pseudomonas aeruginosa to intestinal epithelial cells. Methods The intestinal epithelial cells were cultured,then divided into three groups: control,Pseudomonas aeruginosa adhesion group,SCS and Pseudomonas aeruginosa adhesion group. The effects of SCS on cell viability,the number of adhering and invasive bacteria were evaluated with MTT assay and lysis-counting assay in 1,3,6 h. Results At 3 h after SCS treatment,the amount of Pseudomonas aeruginosa decreased significantly,and the number of adhering and invasive bacteria decreased by 71% and 87% respectively. Conclusion SCS could protect the intestinal epithelial cells by inhibiting the adhesion and invasion of Pseudomonas aeruginosa.
5.Helical CT Scan:the Value in the Diagnosis of Small Renal Cell Carcinoma
Wenzhao ZHONG ; Yixiong CHEN ; Jun XIA
Journal of Practical Radiology 2001;0(05):-
Objective To evaluate the value of helical CT scan in the diagnosis of small renal cell carcinoma.Methods The helical CT features of small renal cell carcinoma proved by operation and pathology in 14 cases were studied retrospectively.Results CT showedisodense mass in 7 cases,slightly low density mass in 5 cases,slightly hyperdense mass in 1 case,cystic and solid mass in 1 case,and among them 2 cases showed punctural calcification.The lesions showed marked enhancement in cortical phase in 12 cases,slight to moderateenhancement in 2 cases,in parenchymal phase,the tumor density dropped promptly,and in the pelvic phase the tumor density droppedfurther. Conclusion Small renal cell carcinoma is of certain characteristic on multi-phasic spiral CT contrast-enhanced scan,it is a very valuable method in diangosis of small renal cell carcinoma.
6.The relationship between restoration and furcation involvement on molar teeth
Jiuyu GE ; Tiemei WANG ; Jun Zhang ; Jun JI ; Xia Chen
Journal of Practical Stomatology 1995;0(04):-
Objective: To investigate the correlation between the presence of a crown (CR) or a proximal restoration (PR) and furcation involvement (FI) on molars. Methods: Data were collected from 237 teeth in 44 patients who had restored and non-restored molars with or without FI.The clinical examinations were conducted on the molars including CR,PR,FI, mobility(MO), endodontic treatment(EN) and probe of periodontal attachment level(PAL). Results: Molars with CR or PR had a significantly highter percentage of FI (P0.05) when compared to molars without restorations. Conclusion: The molars with crowns or restorations involving the proximal tooth surfaces have a highter prevalence of FI and more periodontal attachment lose than molars without restorations.
7.Inhibitory effects and mechanism of arsenic trioxide on the growth of melanoma B16 cells
Jun XIA ; Junxia CHEN ; Lihua YU ; Xiuyun CUI ; Zhiwe CHEN
Chinese Pharmacological Bulletin 2003;0(09):-
Aim The present study was designed to investigate the growth inhibition and anti-angiogenesis of arsenic trioxide (As 2O 3) on B16 cells xenografts in C57BL/6J mice and observe the effects of As 2O 3 on cell proliferation, cell morphology, cell cycle and apoptosis in vitro. Methods Mice melanoma cell line B16 was transplanted into C57BL/6J mice. The weight of tumor and percent of tumor development were examined after As 2O 3 intraperitoneal administration. HE staining and immunohistochemistry for Ⅷ-R Ag were performed to detect the microvessel density in tumor tissues. CellTiter 96 Aqueous One was used to determine the cell proliferation. Giemsa and Feulgen staining were used to observe the morphological changes of the cells. Cell cycle and apoptosis were analyzed by flow cytometry (FCM). Results As 2O 3 significantly inhibited the tumor growth in vivo, with an inhibitory rate of 81.61%. The microvessel density in tumor tissues was obviously reduced after treated with As 2O 3. There was obviously a concentration-dependent relationship between As 2O 3 and the inhibition of B16 cells proliferation (P
8.Volumetric MRI analysis of the amygdala and hippocampus in subjects with major depression.
Jun, XIA ; Jun, CHEN ; Yicheng, ZHOU ; Jingfeng, ZHANG ; Bo, YANG ; Liming, XIA ; Chengyuan, WANG
Journal of Huazhong University of Science and Technology (Medical Sciences) 2004;24(5):500-2, 506
In order to explore the MRI volume of the amygdala and hippocampus in patients with major depression, quantitative MRI of the amygdala and hippocampus were studied in 22 patients with major depression and compared with 13 age-matched controls. The results showed that both groups exhibited similar significant hippocampal asymmetry (left smaller than right). The volume of the bilateral hippocampus was significantly smaller in the major depression group than that in control group. The patients had significant asymmetry of the amygdalar volumes (right smaller than left). No correlation was found between hippocampal volume abnormalities and ill duration. It was concluded that the hippocampus and amygdala within limbic-cortical networks may play a crucial role in the pathogenesis of major depression.
Amygdala/*pathology
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Anthropometry
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Depressive Disorder, Major/*pathology
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Hippocampus/*pathology
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Magnetic Resonance Imaging
9.Investigation of the strategies and effect of serf-management of chronic pain for aged people
Mingxia CHEN ; Qin XU ; Xuezhou XIA ; Jun ZHANG ; Shuqin ZHU
Chinese Journal of Practical Nursing 2008;24(24):65-67
Objective To discuss the clinical feature of chronic pain of aged people and strategies and effect of its self-management as well as their relationship.Methods Investigation with questionnaires wag carried out in 243 aged people who were above 65 years old to understand the clinical feature of chronic pain and strategies of its self-management.The results underwent analysis.Results Non-narcotic analgesics,physical exercise,cold and heat therapy and spiritual activity were used most frequently in selfmanagement of pain.No statistical difference existed in the use of self-management strategies between people in different age groups.Effect of self-management strategies was negatively correlated with degree of pain,interrupting with daily life and anxiety,but Wag positively correlated with self-efficacy score.Conclusions Aged people ale willing to attemp various strategies to cope with chronic pain.We should pain attention to the standardization of physical exercise,confrontation of anxiety and improvement of self-efficacy to improve the effect of self-management.
10.The effect of nursing intervention on postnral hypotension of aged with heart disease
Fengguang PENG ; Xia WEI ; Jun YUAN ; Minzhi CHEN
Chinese Journal of Primary Medicine and Pharmacy 2008;15(3):414-415
Objective To study the effect of nursing intervention on postural hypotension of aged with heart disease.Methods Nursing intervention were gived to the 68 aged patients with heart disease and postural hypotension.The effect of nursing intervention on postural hyporension and hypotension associated symptoms were observed.Results The postural hypotension was improved and the incidence of hypotension associated symptoms were reduced after nursing intervention.Differences were statistically significant(P<0.01).Conclusion Nursing intervention was effective on the improvement of postural hypotension.