Objective:To investigate serum level of vascular endothelial growth factor(VEGF)in patients with rheumatoid arthritis(RA).Methods:VEGF ELISA Quantikine kit.The serum RF level was also d etermined using Beckman Array 360.Results:The serum concen tration of VEGF was significantly higher in patients with RA than in healthy co ntrol(P＜0.01).Conclusion:It suggests that VEGF is involved in the pathog enesis of RA and that measurment of serum concentration of VEGF is noninvasive, usful method for monitoring the disease activity of RA.

Arthritis, Juvenile ; classification ; diagnosis ; therapy ; Child ; Female ; Follow-Up Studies ; Humans ; Male ; Prognosis

Esophagus ; Foreign Bodies ; Humans ; Male ; Middle Aged

AIM To examine the effects of lovastatin, probucol on the intracellular cholesterol content and cholesterol efflux. METHODS With the model of foam cells through depositing the oxidized low-density lipoprotein (OXLDL) into mouse peritoneal macrophages, intracellular cholesterol content was examined by high performance liquid chromatography after the administration of lovastatin and probucol at different concentration. RESULTS The CE/TC ratios of the model group were beyond 50% and extremely higher than those of the normal and negative groups, suggesting that the model of foam cells was established triumphantly. Lovastatin decreased intracellular TC, CE and CE/TC significantly and dose-dependently. Probucol also possessed such effects on intracellular TC, CE, but no dose-dependently, and no effect on the ratio of CE/TC. CONCLUSION The results showed lovastatin might be conducive to plagues stability by increasing cholesterol efflux from the foam cells and decreasing the intracellular cholesterol content. Probucol did not have this effect although it decreased intracellular TC and CE content.

Adult ; Computer-Aided Design ; Humans ; Male ; Malocclusion ; diagnostic imaging ; therapy ; Orthodontic Appliance Design ; Orthodontic Brackets ; Orthodontic Wires ; Radiography, Panoramic

Adolescent ; Humans ; Kearns-Sayre Syndrome ; Male

Carcinoma, Squamous Cell ; pathology ; therapy ; Female ; Humans ; Neoplasm Invasiveness ; Uterine Cervical Neoplasms ; pathology ; therapy

Anti-Bacterial Agents ; administration & dosage ; therapeutic use ; Chest Tubes ; Erythromycin ; administration & dosage ; therapeutic use ; Humans ; Infant, Newborn ; Male ; Thoracic Cavity ; drug effects ; pathology ; Thoracic Diseases ; pathology ; therapy ; Treatment Outcome

Objective To investigate the correlation between executive function(EF) and characteristic of symptom in children with Tourette′s syndrome(TS).Methods EF were measured with Wisconsin Card Sorting Test(WCST) in 53 patients with TS,and symptom characteristics were evaluated with Achenbach Child Behavior Checklist(CBCL) and Yale Global Tic Severity Scale(YGTSS).Results Compared with healthy control,TS had poor executive performances significantly in WCST(all P

0.05),and the expression of HoxB5 in the model group tapered after the 7th day,but the expression of HoxB5 increased and reached the peak on the 7th day and expressed in a stable level in the control group and were significantly higher than those of model group(Pa