1.The reliability and validity of Chinese version of the rejection sensitivity questionnaire
Chinese Journal of Behavioral Medicine and Brain Science 2012;21(8):757-759
ObjectiveTo assess the reliability and validity of the Chinese version of the rejection sensitivity questionnaire(RSQ).Methods813 college students were investigated with RSQ and each caregiver was retested 4 weeks later.Results ( 1 ) All items had good discrimination.(2) Exploratory factor analysis showed the Chinese version of RSQ consisted of three factors which could explain 45.986% of the total variance.Confirmatory factor analysis indicated that there was high fitting degree between the three-factor model and the two-dimension model.They were significantly correlated with RSQ total score( r =0.661 ~ 0.851,P < 0.001 ).(3) The Cronbach's alpha coefficient was 0.809.The three factor's Cronbach's alphas were 0.684,0.631 and 0.534 respectively.The test-retest coefficient was 0.892 (P < 0.001 ).ConclusionThe Chinese version of RSQ is a reliable and valid measurement for assessing the rejection sensitivity of the Chinese college students.
2.Treatment of Hyperlipidemia by Acupuncture and Cupping Method on Back-shu Points
Journal of Acupuncture and Tuina Science 2005;3(1):14-15
Xinshu (BL 15), Feishu (BL 13), Pishu (BL 20), Ganshu (BL 18), Shenshu (BL23) and Geshu (BL 17) were selected and the needles were retained for 30 min. After the needles were taken out, cupping method was applied on each acupoint. In the treatment of total 36 cases of hyperlipidemia, the results showed remarkable effect in 22 cases, effect in 9cases and failure in 5 cases, and the total effective rate in 86.1%.
3.Comment on "Bioethics is love of life"
Chinese Medical Ethics 1994;0(05):-
Professor Macer summarizes the essence and concepts of bioethics with love as the universal ethical basis,but it effective resources and evidence proves to be limited.In fact,the "love" could be the motive of ethics rather than the basis of ethics.For the origins of ethics are vastly related with compassion and mercy.
4.Therapeutic effects of induced pluripotent stem cells on primary open angle glaucoma
Chinese Journal of Experimental Ophthalmology 2017;35(9):773-777
Glaucoma is an group of ocular disease associated with the degeneration of retinal ganglion cells and it finally causes vision loss.Primary open angle glaucoma (POAG) is a main type of glaucoma worldwide.The primary reason of POAG is elevated intraocular pressure (lOP) caused by the degeneration or dysfunction of the trabecular meshwork (TM).Recent studies showed that stem cell-based therapy becomes a promising approach to treat the degenerative diseases,including POAG.Among multiple types of stem cells,induced pluripotent stem cell (iPSC) is the one with the most clinical potential due to its autologous derivation and non-ethical issue.In this paper,we summarized the encouraging therapeutic effects of iPSCs on POAG from different species,different etiological factors and different pathological stages.Although these encouraging studies suggest that iPSC is a fabulous stem cell type to regenerate the damaged tissue,more efforts are required for clinical application.In addition,we discussed several solutions to improve the safety of iPSCs and provided potential approaches to improve the therapeutic efficiency and specific targeting.Answering these questions will help us to better understand the characteristics of iPSCs and promote the development of bench to bedside research.
5.Value of CT histogram analysis in the diagnosis of primary hepatic carcinoma
Journal of Practical Radiology 2014;(10):1733-1735
Objective To explore the application value of CT value histogram in differential diagnosis between primary hepatoma and other space-occupying lesions in liver.Methods From 2012 to 2013,the imaging data in 243 patients with different isolated space-occupying lesions in liver were analyzed retrospectively who underwent both enhanced and unenhanced abdominal CT scans. The lesions were confirmed as hepatic cyst,hepatic hemangioma or primary hepatoma by pathological and other clinical proofs and divided into 3 groups.The histograms of plain scan and post-contrast triphases were drawn respectively using an attached picture-making software.Relevant data of the histograms were analyzed and compared using the SPSS among three groups.Results The CT value histograms of hepatic cysts,hemangiomas and majority of hepatomas presented normal distribution curves.Negative skewness distribution curve was showed in the tumor within necrosis and liquefaction,whereas the positive curve was showed in hepatoma with more calcification.Some significant differences in the Mean,SD,Max,Min,and R values were confirmed.Conclusion Skew-ness distribution curve has a relative high specificity in diagnosis of primary hepatoma.Both dramatic decrease of the Mean value in delayed phase and obvious increase of the R value in plain scan suggest the possibility of primary hepatoma.
6.Factors influencing the assay of ?_1-antitrypsin bioactivity
Chinese Journal of Blood Transfusion 1988;0(04):-
Objective To study the factors influencing the assay of ? 1 antitrypsin(? 1 AT) bioactivity. Methods Various concentrations of PEG(MW, 4000), sucrose, sodium citrate and ethanol were added before determining ? 1 AT activity. Results ? 1 AT activity increased approximately 100% compared with the controls when the PEG concentration reached 20%. Conclusion PEG concentration influences the ? 1 AT activity assay.
7.Research progress of pathogenic mechanism of congenital neutropenia.
Chinese Journal of Pediatrics 2012;50(11):868-871
Adaptor Proteins, Signal Transducing
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genetics
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Bone Marrow Diseases
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genetics
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pathology
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DNA Mutational Analysis
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DNA-Binding Proteins
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genetics
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Exocrine Pancreatic Insufficiency
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genetics
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pathology
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Glucose-6-Phosphatase
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genetics
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Humans
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Leukocyte Elastase
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genetics
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Lipomatosis
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genetics
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pathology
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Mutation
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Neutropenia
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congenital
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genetics
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Proteins
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genetics
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Transcription Factors
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genetics
9.Progress on the killer immunoglobulin-like receptor in the acute rejection response with kidney transplantation
International Journal of Surgery 2009;36(2):103-106
The success of organ transplantation depends on the prevetion of acute rejection. T and B lymphocytes, the major components of the cellular and humoral immunization mediating the rejection response, respectively, have been extensively studied. The importance of matural killer(NK) cells in transplantation has become an increasing area of interest as reagents for their study have become available. Basing on this on the killer immunoglobulin-like receptor in the acute rejection response with kidney transplantation.
10.Inhibitory effects of docosahexaenoic acid on the growth of incubated human pancreatic cancer cell lines
Chinese Journal of Clinical Nutrition 2009;17(1):49-52
Objective To investigate the effects of docosahexaenoic acid (DHA) on the growth of human pancreatic cancer cell lines. Methods Human pancreatic cancer cell lines Patu8988 and SW1990 were treated with DHA. The cell proliferation was evaluated by MTT assay. Cell cycle, apoptosis, and cyclooxygenase-2 ex-pression were evaluated by flow cytometry. Results After incubation of pancreatic cancer cell with DHA for 24 to 72 hours, cell proliferation significantly decreased (P<0. 01) and apoptosis increased, both of which were time- dependent and dose-dependent After incubation with 50μg/ml DHA for 24 hours, cyclooxygenase-2 expression of pancreatic cancer cell lines significantly decreased (P < 0. 05). Conclusions DHA can inhibit the growth of hu- man pancreatic cancer cells via decreasing cell proliferation and inducing apoptosis. These effects may be associat- ed with the decrease of cyclooxygenase-2 expression.