1.The reliability and validity of Chinese version of the rejection sensitivity questionnaire
Chinese Journal of Behavioral Medicine and Brain Science 2012;21(8):757-759
ObjectiveTo assess the reliability and validity of the Chinese version of the rejection sensitivity questionnaire(RSQ).Methods813 college students were investigated with RSQ and each caregiver was retested 4 weeks later.Results ( 1 ) All items had good discrimination.(2) Exploratory factor analysis showed the Chinese version of RSQ consisted of three factors which could explain 45.986% of the total variance.Confirmatory factor analysis indicated that there was high fitting degree between the three-factor model and the two-dimension model.They were significantly correlated with RSQ total score( r =0.661 ~ 0.851,P < 0.001 ).(3) The Cronbach's alpha coefficient was 0.809.The three factor's Cronbach's alphas were 0.684,0.631 and 0.534 respectively.The test-retest coefficient was 0.892 (P < 0.001 ).ConclusionThe Chinese version of RSQ is a reliable and valid measurement for assessing the rejection sensitivity of the Chinese college students.
2.Value of CT histogram analysis in the diagnosis of primary hepatic carcinoma
Journal of Practical Radiology 2014;(10):1733-1735
Objective To explore the application value of CT value histogram in differential diagnosis between primary hepatoma and other space-occupying lesions in liver.Methods From 2012 to 2013,the imaging data in 243 patients with different isolated space-occupying lesions in liver were analyzed retrospectively who underwent both enhanced and unenhanced abdominal CT scans. The lesions were confirmed as hepatic cyst,hepatic hemangioma or primary hepatoma by pathological and other clinical proofs and divided into 3 groups.The histograms of plain scan and post-contrast triphases were drawn respectively using an attached picture-making software.Relevant data of the histograms were analyzed and compared using the SPSS among three groups.Results The CT value histograms of hepatic cysts,hemangiomas and majority of hepatomas presented normal distribution curves.Negative skewness distribution curve was showed in the tumor within necrosis and liquefaction,whereas the positive curve was showed in hepatoma with more calcification.Some significant differences in the Mean,SD,Max,Min,and R values were confirmed.Conclusion Skew-ness distribution curve has a relative high specificity in diagnosis of primary hepatoma.Both dramatic decrease of the Mean value in delayed phase and obvious increase of the R value in plain scan suggest the possibility of primary hepatoma.
3.Comment on "Bioethics is love of life"
Chinese Medical Ethics 1994;0(05):-
Professor Macer summarizes the essence and concepts of bioethics with love as the universal ethical basis,but it effective resources and evidence proves to be limited.In fact,the "love" could be the motive of ethics rather than the basis of ethics.For the origins of ethics are vastly related with compassion and mercy.
4.Therapeutic effects of induced pluripotent stem cells on primary open angle glaucoma
Chinese Journal of Experimental Ophthalmology 2017;35(9):773-777
Glaucoma is an group of ocular disease associated with the degeneration of retinal ganglion cells and it finally causes vision loss.Primary open angle glaucoma (POAG) is a main type of glaucoma worldwide.The primary reason of POAG is elevated intraocular pressure (lOP) caused by the degeneration or dysfunction of the trabecular meshwork (TM).Recent studies showed that stem cell-based therapy becomes a promising approach to treat the degenerative diseases,including POAG.Among multiple types of stem cells,induced pluripotent stem cell (iPSC) is the one with the most clinical potential due to its autologous derivation and non-ethical issue.In this paper,we summarized the encouraging therapeutic effects of iPSCs on POAG from different species,different etiological factors and different pathological stages.Although these encouraging studies suggest that iPSC is a fabulous stem cell type to regenerate the damaged tissue,more efforts are required for clinical application.In addition,we discussed several solutions to improve the safety of iPSCs and provided potential approaches to improve the therapeutic efficiency and specific targeting.Answering these questions will help us to better understand the characteristics of iPSCs and promote the development of bench to bedside research.
5.Treatment of Hyperlipidemia by Acupuncture and Cupping Method on Back-shu Points
Journal of Acupuncture and Tuina Science 2005;3(1):14-15
Xinshu (BL 15), Feishu (BL 13), Pishu (BL 20), Ganshu (BL 18), Shenshu (BL23) and Geshu (BL 17) were selected and the needles were retained for 30 min. After the needles were taken out, cupping method was applied on each acupoint. In the treatment of total 36 cases of hyperlipidemia, the results showed remarkable effect in 22 cases, effect in 9cases and failure in 5 cases, and the total effective rate in 86.1%.
6.Factors influencing the assay of ?_1-antitrypsin bioactivity
Chinese Journal of Blood Transfusion 1988;0(04):-
Objective To study the factors influencing the assay of ? 1 antitrypsin(? 1 AT) bioactivity. Methods Various concentrations of PEG(MW, 4000), sucrose, sodium citrate and ethanol were added before determining ? 1 AT activity. Results ? 1 AT activity increased approximately 100% compared with the controls when the PEG concentration reached 20%. Conclusion PEG concentration influences the ? 1 AT activity assay.
7.Research progress of pathogenic mechanism of congenital neutropenia.
Chinese Journal of Pediatrics 2012;50(11):868-871
Adaptor Proteins, Signal Transducing
;
genetics
;
Bone Marrow Diseases
;
genetics
;
pathology
;
DNA Mutational Analysis
;
DNA-Binding Proteins
;
genetics
;
Exocrine Pancreatic Insufficiency
;
genetics
;
pathology
;
Glucose-6-Phosphatase
;
genetics
;
Humans
;
Leukocyte Elastase
;
genetics
;
Lipomatosis
;
genetics
;
pathology
;
Mutation
;
Neutropenia
;
congenital
;
genetics
;
Proteins
;
genetics
;
Transcription Factors
;
genetics
8.Interventional therapy for complex intracranial aneurysms
International Journal of Cerebrovascular Diseases 2009;17(6):470-474
Complex intracranial aneurysms refer to huge aneurysm, wide-necked aneurysm, fusiform aneurysm, microaneurysm, dissecting aneurysm and pseudoaneurysm.Endovascular interventional therapy is one of the safe and effective methods for intracranial aneurysms. However, the treatment is still limited by the morphology and is challenged by the recurrence for most of the complex intracranial aneurysms. The article reviews the treatment progress of complex intracranial aneurysms.
9.Analysis of pregnancy outcome of category Ⅱ fetal heart rate tracing
Chongqing Medicine 2014;(11):1320-1322
Objective To explore the potential risk of category Ⅱ fetal heart rate(FHR) tracing according to the latest electron-ic fetal monitoring tracings .Methods The prenatal fetal heart rate tracings in 400 parturients with hospitalized delivery in this hos-pital from November 2011 to October 2012 were classified by category .Among them ,the pregnancy outcomes were compared be-tween the category Ⅰ FHR tracings(control group) and category Ⅱ FHR tracings(observation group) .Results The case number of meconium-staining amniotic fluid ,cesarean rate ,hypamniony and umbilical cord abnormality was significantly higher than that of the control group with statistical difference between the two groups (P<0 .05);the case number of neonatal asphyxia ,aging of pla-centa and neonatal death had no statistical difference between the two groups (P>0 .05);among the groups with various fetal heart monitoring abnormalities ,the rate of meconium-staining amniotic fluid in the decreased variation group was significantly higher than that in the fetal tachycardia group ,the difference showing statistical significance (P<0 .05);the rate of meconium-staining amniotic fluid in the fetal tachycardia group was significantly higher than that in the prolonged acceleration and ineffective acceleration group with statistical difference (P< 0 .05);the pregnant outcomes had no statistical differences among the other groups .Conclusion Compared with the category Ⅰ FHR tracings ,the category Ⅱ FHR tracings indicate a potential risk to the fetus ,which need to strengthen the prenatal and intrapartum fetal monitoring .
10.Effect of continuity of midwifery service model on delivery outcomes in pregnant women
Chinese Journal of Practical Nursing 2017;33(7):516-519
Objective To explore the effect of continuity of midwifery service model on delivery outcomes in pregnant women. Methods From January 2015 to June 2016,100 single pregnant women with full-term and cephalic presentation who accepted midwife outpatient education were selected from our hospital and divided into observation group, at the same time,100 cases of full-term and cephalic presentation accepting obstetrics regular check as control group. Both delivery methods and total labor time were compared between two groups; the rates of episiotomy, weight gain during pregnancy, postpartum hemorrhage, neonatal asphyxia and macrosomia were all observed. Results The observation group maternal weight gained, the total labor time were (12.26±0.95) kg, (445.21±246.34) min, the control group were (14.48± 1.89) kg, (642.26±258.81) min, there wwa significant difference (t=-10.534,-3.456, P < 0.01).The observation group cesarean section rate, postpartum hemorrhage rate, the rate of fetal macrosomia were 29%(29/100), 2%(2/100), 3%(3/100), the control group were 45%(45/100),10%(10/100),12%(12/100), there was significant difference (χ2=7.040, 5.674, 5.838, P<0.05). In the observation group, the rate of perineal resection were 26% (26/100) and 0 respectively, the control group were 30%(30/100) and 2% (2/100), there was no difference between the two groups (χ2=1.109, 2.020, P > 0.05). Conclusions Continuous care provided by midwife can effectively promote natural birth, reduce the incidences of macrosomia and postpartum hemorrhage, enhance the quality of obstetric services, is worth promoting in clinical application.