Objective To observe and analyze the euthyrox intervention effect of early hypothyroidism after 131I therapy for hyperthyroidism. Methods 200 cases of patients with hyperthyroidism in our hospital from March 2014 to April 2016 were selected as the object of the experiment needs, all the patients were randomly divided into two groups, respectively into study group and control group, two groups there are 100 patients. All patients before admission were accepted 131I treatment, control group received routine treatment, the study group was treated with 131I in twentieth days after start of continuous use of euthyrox, 20 days of continuous use, the two groups of patients with thyroid ultrasound, thyroid gland imaging, thyroid function and perturbation the rate of iodine was detected and observed. And the two groups of patients in the clinical efficacy of different after treatment were compared. Results The patients in the study group and the control group in 3 months after treatment, 9 months and 12 months the incidence of hypothyroidism were compared, research The incidence rate of hypothyroidism group was significantly lower than the control group, the differences between the groups were statistically significant (P<0.05). Patients in the study group and the control group at the same time, the cure rate of hyperthyroidism compared to the study group was significantly higher than that of control group, with statistical significance (P<0.05). Conclusion In patients with early after 131I treatment for patients taking euthyrox can to some extent reduce the occurrence of hypothyroidism, but also can improve the cure rate of hyperthyroidism for the first time, a higher application value.

[Objective] To discuss the operation mode of thyroid tiny papil ary caracinoma and offer foundation for clinical choice. [Method] Make analysis on the clinical data and fol ow-up results of 176 cases of the disease above. [Result] Al were made operation, and there ’re no death. Compare the resec-tion of deseased gland and isthmus with ful resection of the thyroid, the difference of hoarse sound and low-calcium occurrence rate had statistical mean-ing; on uni-lateral and double lateral central ALND, the hoarse sound and low-calcium occurrence rate had no marked statistical meaning. [Conclusion] The diseased gland and isthmus resection+double lateral ALND not only doesnt ’increase post-operation complications, but improves patients ’life quality, which is the main operation for thyroid tiny papil ary carcinoma.

Bombesin in central nervous system (CNS) is closely related to thermoregulation. Injection of bombesin into some parts of brain caused hypothermia significantly, especially in POAH, and this effect can be enhanced by the cold ambient temperature. The mechanism might be suppress heat production and disrupt the regulatory function of thermoregulatory centre. Morever, other neuropeptides, food deprivation and lesion of VMH (ventromedial hypothalamus) affected the action of bombesin.

The article reviewed the concept of normal binocular vision and general examination methods of binocular vision and its normal range.New investigation progresses about monocular and binocular depth perception in neuro-physiology and neuro-anatomy were introduced.The depth perception from monocular and binocular depth cues was integrated in parietal area of caudal intraparietal sulcus(CIP).Mono-eye also had depth perception.Strabismus and amblyopia could damage the binocular vision and binocular depth perception.Binocular vision damage and its treatment results with doffing suppression training,fusion training,and stereopsis training in strabismus and amblyopia patients were explained in detail in this article.

The differentiation of cells types and layers in the cerebellar cortex of 74 white micefrom the time of birth to the adult age were observed by the methods of Nissl, Golgi,Cajal and Golgi-Cox. The external granular layer of the folia of the cerebellar cortex attained the greatestthickness in the fourth on the fifth day; at the same time, mitosis was seen. There after,this layer became gradually thinner; from eighteenth to twentieth day after birth it even-tually disappeared. Some cells of the external granular layer differentiated into granular and stellatecells. The Purkinje cells after birth were in primitive form with perisomatic dendrites.From the eighth day on, perisomatic dendrites became atrophic and disappeared. In thethird week, the Purkinje cells reached the mature stage. The Purkinje cells after birth, besides the ones in their normal position, might befound in the submeningeal spaces, external granular layer, molecular layer, internal granu-lar layer and medulla of the cerebellum. A part of these displaced cells may be origi-nated from the external granular layer. With the disapperance of the external granular layer, the Purkinje cells becamecompletely matured. In accordance the animals in this period began to be able of in-dependent activities, such as running, jumping, etc.

Objective To understand the epidemiological characteristics of bacillary dysentery and etiological characteristics of Shigella in Tianjin, and to provide evidence for the prevention and control measures. Methods The data of disease surveillance information reporting system from 2008 to 2014 were analyzed retrospectively. A total of 3955 stool samples came from the clinically diagnosed cases of bacillary dysentery were collected, according to the extraction method of stratified sampling in Tianjin city, suburban area, Binhai New Area and suburban area sentinel hospitals, and according to the sampling interval for the May to October from 2008 to 2014. Samples were detected and cultured for Shigella flora. Results (1) Epidemiological characteristics:from 2008 to 2014, a total of 65179 cases of bacillary dysentery were reported in Tianjin city, with an average annual incidence of 72.00/100 thousand. The annual incidence rate showed a downward trend year by year. The incidence was a downward trend, including urban (120.28/100 thousand), suburban areas (70.36/100 thousand), Binhai New Area (64.22/100 thousand) and the outer suburbs (19.39/100 thousand). The onset time was mainly concentrated in June-September, and the peak incidence occurred in August. The incidence rate was higher in people below 5 years old and above the age of 85. The annual incidence rate was higher in male patients of 0 to 24 years old and above 75 years old than that of female. The annual incidence rate was higher in female patients of 50 to 74 years old age group than that of male (P<0.05). The distribution of occupation was scattered among children and retirees. (2) Distribution of bacteria:the 229 Shigella strains were positive (5.79%), including 136 strains of Shigella sonnei (59.39%), 93 strains of Shigella flexneri (40.61%). The 89 strains of Shigella flexneri (4 strains were not detected) were detected in 8 subtypes, F2a (49.44%), F2b (22.47%) and FX (13.48%). The subtypes of Shigella flexneri were detected decreased year by year from 2008 to 2014, showing a single subtype. The highest detection rate of Shigella was found in 10-19 years old (9.55%). The S.sonnei positive rate was the highest in urban (5.09%), and the Shigella flexneri positive rate was the highest in suburban areas (3.09%). Conclusion The key population for the prevention and control of bacillary dysentery in Tianjin is scattered children and old people. It is necessary to strengthen the propaganda and health education to improve the health consciousness of the key population and their daily nursing staff. With the continuous changes of Shigella flora, it is necessary to carry out long-term monitoring to find out the regularity of shigella.

Based on the requirements of Good Preparation Practice in Medical Institutions(GPP) and considering the actual conditions of the hospital,we decided upon a right way in the reconstruction of the hospital's preparation room and amelioration of the equipment and apparatus that constituted 30% of the investment.The results were reduced investment,higher efficiency,with perfect conformity to the GPP requirements.

Reforming the managerial system and the educational system of higher medical education is the requirement of the social development in the twenty-first century. The article expounds the fundamental characteristics of medical education including small scale, longer-duration program, and high expenditure. It emphasizes the significance of following the rule of medical education, and analyzes the important position of medical college and the relation of medical college to affiliated hospitals and other related colleges in the comprehensive university. Based on the requirement of the social development and the trend of higher medical education internationalization, it also analyzes the necessity of the adjustment on the medical educational system and the way of the adjustment.

In the teaching of pathology,instructor guides students to identify the similar and different spots between affection and normal tissue by previewing and contrasting teaching,so students learn how to discriminate different forms of affection generally and under the microscopic,and associated the clinical symptom.These exercises conduce to cultivate the logical thinking,observation and practice capability of students and do the groundwork for the clinic study.

Objective To evaluate the efficacy and safety of TACE combined with Apatinib versus TACE monothcrapy in the treatment of advanced hepatocellular carcinoma (HCC).Methods A total of 44 patients with advanced HCC were enrolled and divided randomly into group A (n=22) and group B (n=22).The patients in group A were treated with TACE monotherapy while group B were treated with TACE combined with Apatinib.The serum alpha fetoprotein (AFP) levels were compared between the two groups three months after treatment.The objective response rate (ORR) after 3,6,9 and 12 months,the progression-free survival (PFS) and incidence of adverse reactions were also compared.Results The serum AFP levels decreased apparently in two groups three months after treatment,and statistic differences were observed in each group (Z=-2.289,-2.953,both P ＜0.05),while no statistic differences was obtained between the two groups after treatment (Z=-0.126,P＞0.05).No statistic differences were found in ORR between the two groups 3 and 6 months after treatment (both P ＞0.05),while statistic differences were manifested after 9 and 12 months (both P ＜0.05).The medium PFS in group A significantly lower than that in group B (x2 =6.576,P=0.01).The apatinib-related adverse reactions including hypertension,hand-foot syndrome and proteinuria in group B were higher than those in group A,and statistically significant difference were obtained (allP＜0.05).The adverse reactions were relieved after symptomatic treatment.Conclusion TACE combined with apatinib may improve the mid-long term efficacy in patients with advanced HCC.And the relatively safety of TACE combined with apatinib is confirmed.