1.The use of home-made blenderized diet in nutritional support in old comatose patients
Limei HUA ; Xiaojun LIU ; Wei GAO
Parenteral & Enteral Nutrition 1997;0(02):-
Objective: To observe the effect of home-made blenderized diet on nutritional support in old comatose patients.Methods: Sixty-three old comatose patients were fed with home-made blenderized diet by nosal gastric feeding.Triceps skinfolds were measured every month.The serum levels of albumin,pre-albumin,total number of lymph cells and hemoglobin were analysed every month.Results: No side effects of abdominal pain,dearrhea,nausea and vomiting were observed in the fed patients.The states of nutrition(such as triceps skinfolds,albumin,pre-albumin,total number of lymph cells and hemoglobin) were improved significantly after home-made blenderized diet.Conclusion: The home-made blenderized diet can support the old comatose patients effectively.
2.Application of internal fixation combined with external fixator for unstable pelvic fracture.
Jin-hua GAO ; Wei HU ; Xiao-shan GUO
China Journal of Orthopaedics and Traumatology 2015;28(8):753-756
OBJECTIVETo invesitigate the clinical effects of percutaneous closed reduction and cannulated screw internal fixation combined with external fixation in the treatment of unstable pelvic fractures.
METHODSFrom April 2006 to May 2009,29 patients with pelvic fractures of rotatory instability were treated with closed reduction and screw internal fixation combined with external fixation. There were 19 males and 10 females with an average age of 31 years old (ranged from 19 to 53 years). Based on the Tile classification,17 cases were type CI and 12 case were type C2. Tornetta standard and Majeed score were used to evaluated the clinical effect after operation.
RESULTSAll patients were followed up from 10 to 24 months with an average of 16 months. There were no nerve injuries and other organ injuries, only one case of infection was found and it was cured with wound dressing. Time of fracture union was from 14 to 18 weeks with the mean of 16.2 weeks. No loosening, slippage or breakage of the screw were found. According to the Tornetta standards,14 cases obtained excellent results, 10 good, 4 fair and 1 poor. The Majeed score was 87.2 ± 11.3, 16 cases got excellent results, 9 good and 4 fair.
CONCLUSIONClosed reduction and screw internal fixation combined with external fixation is an effective way to treat unstable pelvic fractures with Tile type C1 and Tile type C2.
Adolescent ; Adult ; Child ; External Fixators ; Female ; Fracture Fixation, Internal ; methods ; Fractures, Bone ; surgery ; Humans ; Male ; Middle Aged ; Pelvic Bones ; injuries ; surgery
4.Effects of basal rate verification on CSⅡ dose adjustments in brittle diabetes
Wei SUN ; Zhiqiang LU ; Xia HUA ; Xin GAO
Chinese Journal of Endocrinology and Metabolism 2013;(1):26-28
Basal rate verification is the process to find and verify the basal rate of continuous subcutaneous insulin infusion (CSⅡ) required for basal glucose metabolism.In the present study,five cases of brittle diabetes were treated by CSⅡ with Insulin Lispro.After doses were adjusted to reach steady blood glucose levels,basal rate verifying tests were carried out.The results showed that the overall level and stability of blood glucose were improved markedly after CSⅡ.Before and after the verification of the basal rate,there was no significant difference in CSⅡ total doses.Basal rates decreased from 50% of total to 30% (P<0.05),and boluses increased to 70% (P<0.05).The basal rates during lunch and supper time were reduced by half (P<0.05),the boluses of lunch and supper were increased 1.5 times (P<0.05),and square waves were needed to control postprandial blood glucose.These results suggest that the CSⅡ could smoothly control blood glucose level in brittle diabetes without basal rate verification.However,the implementation of the verification could better determine the basal rates for basal glucose metabolism,and thus help to identify diet-related boluses.
5.Study of the counts of T-lymphocyte subgroup in patients with malignant lymphoma
Hua LIU ; Wei WANG ; Chuizhi ZHENG ; Yunsuo GAO
Journal of Leukemia & Lymphoma 2009;18(3):166-168
Objective To detect T-lymphocyte subgroup in patients with malignant lymphoma, and investigate the relationship between the number of the cells and the oncogenesis and development of malignant lymphoma. Methods The counts of T-lymphocyte subgroup in peripheral blood of 106 patients with lymphoma were detected by flow-cytometry, and analyzed in comparison with that of 106 normal people as control. Results The counts of CD+3 cell and the ratio of CD+4/CD+8 in patients with malignant lymphoma were significantly lower than that of control group (P<0.05). The number of CD+3 were significantly lower and CD+8 were higher than that of control group in patients with NHL at early ( Ⅰ, Ⅱ ) stage (P<0.05). The counts of CD+3 CD+4 cell and the rate of CD+4/CD+8 in patients with NHL at advanced (Ⅲ ,Ⅳ) stage were significantly ldwer than that of control group (P<0.05). Conclusion The function of immune is decreased in patients with malignant lymphoma, and these changes had correlation with clinic stage. It is of active significance by detecting T-lymphocyte subgroup in peripheral blood in patients with malignant lymphoma to evaluate the function of immune and find out the relationship between the number of the immune cells and the oneogenesis and development of malignant lymphoma.
6.Expression of 3 markers and its correlation with prognosis of patients with non-small cell lung cancer
Penghua WEI ; Zhipeng SHEN ; Hua WANG ; Suquan QIAN ; Zhi GAO
International Journal of Laboratory Medicine 2017;38(16):2243-2245,2248
Objective To investigate the expressions of ALCAM,IL-17RA and PIK3CA in patients with non-small cell lung cancer,and to investigate the correlation between the above-mentioned indexes and patients′ prognosis.Methods A total of 65 patients with non-small cell lung cancer admitted to the third People′s Hospital in Liaocheng City were selected and were served as study objects.Immunohistochemical staining(S-P) method was used to detect the expression of ALCAM,IL-17RA and PIK3CA in tissues to analyze the difference of expression between different pathological parameters.And 65 patients were followed up after the operation to compare the survival time of patients in the negative expression group and the positive expression group,and to analyze the correlation between ALCAM,IL-17RA and PIK3CA and the prognosis of the disease.Results Among the 65 cases of patients,47 cases were positive for ALCAM with the positive rate of 72.3%,34 cases were positive for IL-17RA with the positive rate of 52.3%;31 cases were positive for PIK3CA with the positive rate of 47.7%.There was significant difference in the expression of ALCAM,IL-17RA and PIK3CA in patients with different pathological types,TNM staging and lymph node metastasis(P<0.05).There was no significant statistical difference in the expression of patients with different genders and ages(P>0.05).The median survival time of patients with positive results of ALCAM,IL-17RA and PIK3CA were lower than those of negative group,and the differences were statistically significant(P<0.05).Conclusion The expression of ALCAM,IL-17RA and PIK3CA increased in non-small cell lung cancer tissues to remind the higher degree of malignancy and poor prognosis.
8.Endotracheal intubation with fluoroscopic guidance for treatment of 5 cases with difficult tracheotomy.
Ling GAO ; Wei-hua LOU ; Jian-zhong SANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2012;47(5):422-423
Female
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Fluoroscopy
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Humans
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Intubation, Intratracheal
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Male
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Middle Aged
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Tracheotomy
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methods
9.Expression of cadherin genes in chronic myeloid leukemia and its significance
Hongqin GAO ; Jingyu WEI ; Hua YAN ; Jianbin YANG
Journal of Leukemia & Lymphoma 2015;24(11):672-675
Objective To explore the expression of cadherin (Cad) genes in patients with chronic myeloid leukemia (CML),and to elucidate the significance of Cad genes in the development of CML.Methods E-Cad and N-Cad gene expression levels in bone marrow mononuclear cells (BM-MNC) from 48 CML patients (29 in chronic phase,19 in progressive phase) were detected by real time quantitative polymerase chain reaction (qRT-PCR).Results Gene expression of E-Cad and N-Cad was detectable in CML BM-MNC.E-Cad gene expression level was lower in progressive CML than that in chronic CML (0.20 ± 0.35 vs 1.19 ± 0.87,P < 0.01),while N-Cad was highly expressed in progressive CML than in chronic CML (0.89 ± 0.45 vs 0.57 ± 0.47,P < 0.05).E-Cad gene expression level was negatively corrclatcd with thc pcrccntagc of peripheral blood progenitor cells (r =-0.705,P < 0.01).Conclusion E-Cad and N-Cad gene expression correlates with the progression of CML,and might be used as an evaluation index for disease development.
10.Short and long-term effects of CSII on diabetes after necrotizing pancreatitis
Wei SUN ; Zhiqiang LU ; Xia HUA ; Xin GAO
Chinese Journal of Endocrinology and Metabolism 2011;27(8):687-689
This paper presents a case of post-pancreatitis diabetes mellitus with seriously damaged islet function. The blood glucose level was successfully controlled by continuous subcutaneous insulin infusion ( CSII )therapy both in short and long terms.