1.Effect Of Electroacupuncture on Migraine
Tong SI ; Sujie ZHANG ; Zhi LI
Chinese Journal of Rehabilitation Theory and Practice 2009;15(3):218-219
Objective To observe the effect of electroacupuncture on migraine. Methods 60 patients were divided into electroacupuncture group (30 cases) who received electroacupuncture, and control group (30 cases) who received local nerve block. Results In the electroacupuncture group, 22 (73.33%) cases were cured, 6 (20.00%) cases were obviously improved, 2 (6.67%) cases were improved. While in control group, 17 (56.67%) cases were cured, 5 (16.67%) cases were obviously improved, 8 (26.67%) cases were improved. There was significant difference between these two groups (P<0.05). The time of treatment was less in the electroacupuncture group than in the control (P<0.05). Conclusion Electroacupuncture is effective on migraine.
3.Advance in biomarkers of lung cancer in diagnosis and targeted therapy.
Jing ZHANG ; Zhi-yong LIANG ; Xuan ZENG ; Tong-hua LIU
Chinese Journal of Pathology 2009;38(8):564-567
Acid Anhydride Hydrolases
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metabolism
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Apoptosis
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Biomarkers, Tumor
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metabolism
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Caspases
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metabolism
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Cell Adhesion Molecules
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metabolism
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Chromosome Deletion
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Drug Delivery Systems
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GPI-Linked Proteins
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metabolism
;
Humans
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Hyaluronoglucosaminidase
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metabolism
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In Situ Hybridization, Fluorescence
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methods
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Lung Neoplasms
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diagnosis
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drug therapy
;
genetics
;
metabolism
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Neoplasm Proteins
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metabolism
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Neoplasm Staging
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Receptor, Epidermal Growth Factor
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metabolism
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Vascular Endothelial Growth Factor A
;
metabolism
4.Advance in pulmonary adenocarcinoma with micropapillary pattern.
Jing ZHANG ; Zhi-yong LIANG ; Tong-hua LIU
Chinese Journal of Pathology 2011;40(3):202-205
Adenocarcinoma
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drug therapy
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genetics
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metabolism
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pathology
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surgery
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Adenocarcinoma, Bronchiolo-Alveolar
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drug therapy
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genetics
;
metabolism
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pathology
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surgery
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Adenocarcinoma, Papillary
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metabolism
;
pathology
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Cadherins
;
metabolism
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Diagnosis, Differential
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Genes, erbB-1
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genetics
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Humans
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Lung Neoplasms
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drug therapy
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genetics
;
metabolism
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pathology
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surgery
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Lymphatic Metastasis
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Mucin-1
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metabolism
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Mutation
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Neoplasm Invasiveness
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beta Catenin
;
metabolism
5.Experience on epidermal growth factor receptor gene mutation analysis in non-small cell lung cancer.
Jing ZHANG ; Jie GAO ; Zhi-yong LIANG ; Tong-hua LIU
Chinese Journal of Pathology 2011;40(10):712-714
Carcinoma, Non-Small-Cell Lung
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genetics
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metabolism
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pathology
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DNA Mutational Analysis
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DNA, Neoplasm
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genetics
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isolation & purification
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Genes, erbB-1
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Humans
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Lung Neoplasms
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genetics
;
metabolism
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pathology
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Mutation
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Paraffin Embedding
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methods
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Polymerase Chain Reaction
;
methods
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Real-Time Polymerase Chain Reaction
;
methods
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Receptor, Epidermal Growth Factor
;
genetics
6.Transcranial approach for resecting spheno-orbital meningiomas
Yong LI ; Ji-Tong SHI ; Yu-Zhi AN ; Ji-Di FU ; Jia-Liang ZHANG ; Tian-Ming ZHANG ;
Ophthalmology in China 2006;0(06):-
Objective To explore the effect and safety of transcranial approach for spheno-orhital meningioma. Design Retro- spective case series. Participants Thirty-two patients being operated with transcranial approach. Twenty-four cases were meningothelial meningiomas, 3 cases were fibrous meningiomas, 1 case was psammomatous meningioma, 2 cases were atypital meningiomas, 2 case were malignant meningiomas. Methods All patients underwent frontal-temporal craniotomy, the involved sphenoid wing bone and peri- orbit were removed to prevent recurrence. The superior orbital fissure and optic canal were decompressed, the dural and periorbital de- feet were repaired by autogenous temporal fascia or artificial dura. Main Outcome Measures Preoperative and postoperative exoph- thalmus and eyeball movement, the extent of tumor resection, the ratio of recurrence. Results The extent of tumor resection: 8 cases were Simpson gradeⅡ, 20 cases Simpson gradeⅢ, 4 cases Simpson grade IV. After surgery, proptosis were improved in all patients, ophthalmoplegia was found in 6 eases. There was no operation-related death or other significant complication. Tumor recurred in 6 cas- es. Conclusions Adequate exposure of the tumor and bony decompression of the cranial nerves can result from transcranial approach, all the involved bone should be removed in order to prevent recurrence. This approach is relatively safe and the ptoptosis are improved significantly. Complete surgical resection is difficult because of the involvement of the orbital apex, superior orbital fissure and cav- ernous sinus.
7.Research progresses in endovascular stent biomaterials.
Zhen-xin ZHAO ; Dao-zhi LIU ; Yi ZHANG
Chinese Journal of Medical Instrumentation 2005;29(6):391-395
This essay is to make brief comments on the physical characteristics, biocompatibility, corrosion resistance, clinical information, existent problems of endovascular stent biomaterials and the developing tendency in future.
Angioplasty
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instrumentation
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Biocompatible Materials
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Stents
8.Clinical analysis of hematologic changes on 25 Brucellosis patients
Changqing TONG ; Bin ZHANG ; Shengchun FANG ; Lei WANG ; Yongping HAN ; Xuejun ZHI
Chinese Journal of Primary Medicine and Pharmacy 2008;15(10):1608-1609
Objective To study the characteristics of hemogram and myelogram with Brucellosis patients.Methods 25 Brucellosis patients' bone marrow and peripheral blood smears were observed,at the same time a deep clinical inverstigation on the patients was conducted. Results The counts of blood cells were decreased in part pa-tients, and a typical lymphocytes were found in peripheral blood of 64% patients. The marrow proliferative activities were normal(92% ) or higher(8% ),and all patients had poisonous granules. Red cell proliferative activities were normal(68% ) or lower(32% ). The counts of megakaryocytes were normal,but the maturity of megakaryocyte was hindered. All patients' histocytes were increased at different degrees. NAP were increased. Conclusion The changes of hemogram and myelogram have clinical significance for diagnosis of Brucellosis, but primary hematologic disease with Brucellosis should be distinguished.
9.Methylation profile of tumor suppressor genes in the cell-free DNA of plasma in hepatocellular carcinoma
Ye ZHANG ; Bin YANG ; Yijun WANG ; Yingtang GAO ; Tong BAI ; Yu BAI ; Zhi DU
Chinese Journal of Clinical Oncology 2013;(23):1436-1440
Objective:This study aimed to detect the special methylation profile in peripheral blood for hepatocellular carcinoma (HCC). Methods:The methylation status of 12 tumor suppressor genes (TSGs) in the plasma of 55 HCCs and 54 chronic liver diseases (CLDs) was tested by methylation-specific PCR (MSP). Results:In HCC, the methylation frequencies were 78.18%in APC, 63.64%in cyclin D2, 58.18% in TFPI2, 49.09% in DKK3, 49.09% in GSTP1, 47.27% in p16, 40.00% in Sigma 14-3-3, 18.18% in SFRP2, 16.36% in ppENK, 9.09% in DKK2, 7.27% in NPTX2, and 5.45% in LHX1. In CLD, the methylation frequencies were 27.78% in APC, 22.22%in cyclin D2, 7.41%in TFPI2, 3.70%in DKK3, 16.67%in GSTP1, 37.04%in p16, 37.04%in Sigma 14-3-3, 11.11%in SFRP2, 20.37%in ppENK, 7.41%in DKK2, 7.41%in NPTX2, and 9.26%in LHX1. The methylation frequencies of APC, cyclin D2, TFPI2, DKK3, and GSTP1 were higher in HCC than in CLD (P<0.01). The methylation index (MI) of the five-gene methylation profile was statistically higher in HCC (median, 0.6;IQR, 0.4-0.8) than CLD (median, 0.2;IQR, 0-0.2) (P<0.01). In HCC, MI was statistically related to the patient's age. Older patients with HCC had a higher MI. No significant correlation was observed between MI and other clinicopathological data. Moreover, MI was not related to the disease free survival and the overall survival in HCC. Conclusion:This five-gene methylation profile may be a promising biomarker for the assistant diagnosis of HCC.
10.Analysis of Chemical Components and Antifungal Activity of Extraction from Conidia of Trichoderma viride LTR-2
Kai CHEN ; He-Tong YANG ; Ji-Shun LI ; Jin-Dong HU ; Guang-Zhi ZHANG ;
Microbiology 1992;0(03):-
To study the chemical components and the antifungal activity of extraction from conidia of Trichoderma viride LTR-2.The extraction were obtained by distilling with Methylene dichloride from conidia of Trichoderma viride LTR-2 cultured on wheat bran solid matrix.Antifungal activity were determined by mycelium growth method.The chemical components of the extraction were analysed by GC-MS,the relative components in the extraction were determined by area normalization.The extraction not only have broad-spectrum control,showed antibiosis against eleven different plant fungal pathogens in PDA dish,such as Rhizoctonia solani,Alternaria brassica,Verticillium dahliae,Macrophoma kawatsukai,Fusarium moniliforme,Botrytis cinerea,Rhizoctonia cerealis,Fusarium oxysporum f.sp.vasinfectum,Bipolaris sorokinana,Fusarium graminearum,Alternaria.mali,but also have high inhibitory effect,and had 89.3% suppressive rate to Rhizoctonia cerealis.About sixty components were separated and identified by GC-MS,majority components were Hydrocarbon,the number of the Hydrocarbon were fourty-three kinds.Ergosterol was the major chemical components of the extract,and has 41.90% content.Other components comprised:Ketone,Organic acid,Alcohol,Ene,et al.Conclusion:The extraction from conidia of Trichoderma viride LTR-2 have antifungal activity.The extration comprised 2H-Pyran-2-one,5,6-dihydro-6-pentyl,it has 2.35% content.reference others literature,2H-Pyran-2-one,5,6-dihydro-6-pentyl may be the suppressive component of the extration.