Antibiotic susceptibility ; Staphylococcus aureus ; Community

Atopic myelitis (AM) is a relatively mild form of myelitis associated with allergic diathesis, and present with predominant sensory manifestations. Lhermitte's sign has been considered as a relatively non-specific clinical sign suggesting demyelinating lesion in cervical cord. Here we report a patient with recurrent AM who presented with isolated Lhermitte's sign, both in first and second attacks. This report suggests that either the diagnosis or recurrence of AM can be frequently underdiagnosed because of its predominant sensory manifestations.
Diagnosis ; Disease Susceptibility ; Humans ; Myelitis* ; Recurrence

Biomarkers ; Disease Susceptibility ; Humans ; Pneumoconiosis ; etiology

Dental caries is a major disease that threaten human's oral healthy severely with the characteristics of high incidence, low rate of treatment and high rate of retreatment. At present, restorative treatment remains the main method for caries treatment. With the development of the Minimally Invasive Cosmetic Dentistry (MICD), reasonable application of various treatment technologies, maximum preservation of tooth tissues and realizing the maximization of treatment effects become problems that call for immediate solution in dental clinics. In addition, there still exist a large number of old restorations that need standard retreatments. Here, some difficulty influence factors of dental caries clinical treatment such as systemic and oral factors, individual caries susceptibility, treatment technologies and materials, retreatment methods of old restorations and technique sensitivity are analyzed, and corresponding processing strategies are also put forward.
Dental Caries ; Dental Caries Susceptibility ; Humans ; Retreatment

As a stable genetic marker of human, blood group is expressed in a polymorphic system in the population. Blood group and pathogens mainly produce effects through the interaction between antigens and antibodies. On the one hand, they can promote pathogen colonization, invasion or evasion of host clearance mechanism, and on the other hand, they can make some hosts less susceptible to corresponding pathogens. By exploring the molecular mechanism between the blood group system and pathogenic microorganisms, it can provide a scientific basis for the treatment of human related diseases and the development of vaccines.
Blood Group Antigens/genetics* ; Disease Susceptibility ; Humans

In an attempt to determine the susceptibility of inbred golden hamsters(Mesocricetus auratus) to the experimental infection with Clonorchis sinensis, twenty-five hamsters were divided into 5 groups and administered orally 5, 10, 20, 30 or 50 metacercariae each. The hamsters were killed on the 45th day after infection. The adult flukes were recovered from all hamsters. The overall recovery rate for the fluke was 57.9 percent with the range of 48.4 percent to 92.0 percent. As the number of the metacercariae given increased, a proportionate decrease in the recovery rate was found. The prepatent period of the fluke in the hamster varied from 16 to 17 days, with the average of 16 days. No significant differences in the development of the flukes were observed. Egg production expressed by EPG, increased step by step as the time elapsed. However, a tendency of decreasing egg laying capacity was observed with the increase of worm burden. It is suggested that the hamster is a suitable final host of C. sinensis.
parasitology-helminth-trematoda ; Clonorchis sinensis ; clonorchiasis ; susceptibility ; golden hamster

An experimental study was undertaken to observe the difference in susceptibility of mouse strains to Metagonimus yokogawai infection by estimating it from worm recovery rate and dimension of worms. It was also studied the effects of prednisolone injection on the chronological pattern of worm recovery in ICR mice. The metacercariae were obtained from sweetfish and 300 in each number were given to 5 strains (CBH, A, DBA, C(57)BL and KK) of mice, and after 7 days period, the worms were collected from their intestine. Prednisolone at the dose of 10 mg/kg was injected to ICR mice every other day from 7 days prior to infection until sacrificed at 6 hours to 35th post-infection day. ICR mice infected with M.yokogawai but untreated were used for controls. The success rate in infection of mice ranged 25.0-83.3% by strains, the worm recovery rate 1.2-18.9%, and the average size of worms 0.554-0.683 mm long and 0.214-0.244 mm wide. The higher rates and larger size of worms were observed in KK and C(57)BL strains than others and the difference was statistically significant. In ICR mice for control, the worm recovery rate until 1 day after infection was relatively high (38-66%) but it became much lower (less than 0.7%) during 1-35 days. However, prednisolone injection brought about persistently high recovery rates (16-80%) until 21 days. It was concluded that the susceptibility to M. yokogawai infection is different by strains of mice but it can be elevated by prednisolone injection probably due to suppression of immune responses in ICR mice.
parasitology-helminth-trematoda ; Metagonimus yokogawai ; susceptibility ; mouse ; immunosupression ; prednisolone

Despite the availability of numerous options for the treatment of depression, treatment-resistant depression remains common. Several patient-related and treatment-related risk factors have been identified as increasing the likelihood of nonresponsiveness to antidepressant treatment including psychiatric and physical comorbidity, the chronic subtype of depression, and treatment nonadherence. Evidence linking many cases of treatment-resistant depression with a diathesis to bipolar disorder has also emerged. This article reviews the current literature regarding the relevance of bipolarity to treatment-resistant depression, with particular attention to the prevalence of bipolarity in treatment-resistant depression.
Bipolar Disorder ; Comorbidity ; Depression ; Disease Susceptibility ; Humans ; Prevalence ; Risk Factors

Aortic Aneurysm, Abdominal ; epidemiology ; Disease Susceptibility ; Humans ; Risk Factors

Shock wave lithotripsy(SWL) has been considered as a contraindication in a patient with bleeding diathesis. However, appropriate pre-treatment made it possible recently. We present a case of ureteral stone patient with hemophilia A which was resolved successfully using SWL and this would be the first report concerning SWL in a hemophilia A patient in our country.
Disease Susceptibility ; Hemophilia A* ; Hemorrhage ; Humans ; Lithotripsy* ; Shock* ; Ureter