3.Issues to address in developing evidence based clinical practice guidelines: experience from evidence-based recommendations for the diagnosis and treatment of cow's milk protein allergy in infants.
Chinese Journal of Pediatrics 2013;51(3):165-167
Animals
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Evidence-Based Medicine
;
Health Knowledge, Attitudes, Practice
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Humans
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Infant
;
Meta-Analysis as Topic
;
Milk Hypersensitivity
;
diagnosis
;
prevention & control
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Milk Proteins
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adverse effects
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Practice Guidelines as Topic
;
standards
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Professional Staff Committees
;
organization & administration
4.Developmental abnormality of the teeth in children: IV: the early clinical treatment principle for the impacted maxillary young permanent incisors with dilaceration.
Chinese Journal of Stomatology 2012;47(11):698-700
Child
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Humans
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Incisor
;
abnormalities
;
Maxilla
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Occlusal Adjustment
;
Orthodontic Extrusion
;
Tooth Abnormalities
;
diagnosis
;
etiology
;
therapy
;
Tooth, Impacted
;
diagnosis
;
etiology
;
therapy
5.Research advances on tissue-engineered corneal endothelial cells transplantation
International Eye Science 2015;(2):219-222
Due to the serious shortage of donor cornea materials and the donor limit, clinical popularization of penetrating keratoplasty is severely restricted. lt is a hot spot of current research that applying tissue engineering in vitro to culture corneal endothelial cells ( CEC ) with high density, regular hexagonal shape and healthy endothelial function. ln this article, we reviewed the latest progress in the study of source of CEC seeder cells, selection of cultivating carries, type of CEC transplantation and immune mechanism that summarized the current research problems and made a prospect to the future.
6.Comparison of bioassay and HPLC for the determination of levofloxacin in plasma
Kaiying SI ; Jingli DUAN ; Baoxia YAN
Chinese Pharmaceutical Journal 1999;(1):43-
OBJECTIVE:The bioassay and HPLC methods were established and compared for the determination of levofloxacin(Lev) in human plasma.METHOD:In bioassay,medium Ⅱ and staphylococcus aureus were used.The HPLC method was chromatographed with a mobile phase of methanol-0.02mol/L potassium dihydrogen phosphate solution (3∶7),the sample was treated by adding 30% trichloroacetic acid to precipitate protein,and detected at 276mm.RESULTS:The average recovery of bioassay was within 95.90%~106.68%,the within-day and day-to-day precisions were below 6%.The average recovery of HPLC was within 97.24%~101.70%,the within day and day-to-day precisions were blow 5%.Lev tablets were given to 6 patients in two ways.Drug concentrations in plasma were determined by bioassay and HPLC assay,respectively,with no significant difference (P>0.05).CONCLUSION:The bioassay was simple,cheap,time saving,and reliable.The HPLC method wsa rapid,sensitive,accurate.The two methods may be selected to use in actual conditions.
9.A analysis on the effect of PRVC mode of ventilator for mechanical ventilation efficiency
Xiaochen SI ; Yan WANG ; Lan QIN
China Medical Equipment 2017;14(5):34-37
Objective:To analyze the advantages of the pressure-regulated volume control (PRVC) mode compared with the traditional continuous mandatory ventilation (CMV) mode about mechanical ventilation efficiency of ventilator.Methods: For the mechanical ventilation situations, the parameters of PRVC mode, V-CMV mode and P-CMV mode under same detecting conditions were tested by using gas analyzer, which based on the ventilation principle of PRVC mode. And then the differences between PRVC mode and CMV modes were analyzed. Results: PRVC mode can supply the almost same tidal volume, and provide lower pressure and higher compliance compare with the V–CMV mode under the same conditions. On the other hand, PRVC mode can supply more tidal volume and slightly higher compliance compare with the P–CMV mode under the same pressure.Conclusion: PRVC mode has combined with the advantages of CMV mode, and it can make sure the target tidal volume, at the same time, reduce the pressure of airway, and improve the compliance for circuit. It also can make the mechanical ventilation to got more efficiency and more safety.
10.Early intensive blood pressure reduction in acute cerebral hemorrhage
Chunhua YAN ; Jindan SI ; Lie WU
International Journal of Cerebrovascular Diseases 2010;18(11):827-830
There are more prognostic factors affecting the patients with cerebral hemorrhage, including bleeding volume, bleeding site, cause of bleeding, and blood pressure regulation during acute phase. Among them, the regulation of blood pressure during acute phase is a man-controlled important factor. However, the ideal blood pressure level has not yet to he determined at present. Therefore, more clinical trials are needed to determine the exact time window of blood pressure management in patients with intracerebral hemorrhage during acute phase and the range of blood pressure control.