1.Clinical application of foldable multifocal intraocular lens
Academic Journal of Second Military Medical University 2000;0(07):-
The implantation of the foldable multifocal intraocular lens,a new pseudophakia intraocular substitute,needs only a small incision and the post-operative complications are rare.The incoming light can be refracted into several fo-cuses.Improved visual acuities both for far and near distance are obtained,which downregulated the glasses-wearing rate.This article summarizes the theories and designs,implantation,clinical application,theropeutic outcomes,and complications of this type of multifocal intraocular lens.
2.Discussion of tumor treatment from the theory of ascending and descending activities of qi.
Chinese Journal of Integrated Traditional and Western Medicine 2015;35(1):104-106
The theory of ascending and descending activities of qi is one basic theory that guides diagnosis and treatment of disease clinically. It has been esteemed by ancient physicians throughout their academic thinking and clinical diagnosis. As a kind of unbalanced disease in the whole body, the basic internal mechanism of tumor formation may be caused by unbalanced ascending and descending activities of qi. Better clinical efficacy is liable to get by applying the theory of ascending and descending activities of qi in cancer treatment. Therefore, we hope to provide a reference for clinicians from the following aspects: historical status and academic value of the theory of ascending and descending activities of qi, case examples and classical prescriptions.
Humans
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Neoplasms
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diagnosis
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therapy
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Qi
4.Safety evaluation of Chinese medicine on tumor therapy.
Rui LIU ; Bao-Jin HUA ; Jie LI
China Journal of Chinese Materia Medica 2013;38(23):4181-4184
As a characteristic tumor therapy in China, Chinese medicine (CM) plays an important position in comprehensive treatment of tumor. It's a critical issue of objective realization, analysis and evaluation of CM safety for scientific decision-making in tumor safe medication and it also is a pivotal issue which affects the international communication. The safety evaluation of CM includes three phases: pre-clinical safety evaluation, clinical trials (micro-dose studies and traditional clinical trials) and post-marketing CM safety assessment. The key point of evaluation should be distinguished among different stages and various types of CM (such as classic formulas, Chinese herbal extracts, etc). Emphasis should be given to chronic toxicity when evaluating oral Chinese herbal , microdose studies and quality control must be underlined while injection is evaluated and more attention should be pay to the dose-effect relationship and time-effect relationship when turned to toxic Chinese medicine , and so as for the toxicity grading study. Moreover, we should constantly improve CM safety assessment method in various stages of tumor treatment, such as introducing the concept of syndrome classification theory, bringing in metabonomics and real-world research method which are similar to the CM therapeutic concept. Most importantly, we must keep its own feature of CM theory when we learn the concept of safety evaluation from abroad. Actively exploring the anti-tumor medicine safety evaluation methods and strategies is of great significance for clinical and experimental research, and it can provide supportability platform to CM's international communication.
Animals
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Combined Modality Therapy
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Humans
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Medicine, Chinese Traditional
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adverse effects
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methods
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Neoplasms
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therapy
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Safety
5.Application of PET-CT in cancers of the digestive tract.
Ru-Tian LI ; Xiao-Ping QIAN ; Bao-Rui LIU
Chinese Journal of Oncology 2007;29(2):81-83
Colonic Neoplasms
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diagnostic imaging
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pathology
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Digestive System Neoplasms
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diagnostic imaging
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pathology
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Esophageal Neoplasms
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diagnostic imaging
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pathology
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Gastrointestinal Stromal Tumors
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diagnostic imaging
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pathology
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Humans
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Positron-Emission Tomography
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methods
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Rectal Neoplasms
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diagnostic imaging
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pathology
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Stomach Neoplasms
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diagnostic imaging
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Tomography, X-Ray Computed
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methods
6.Advances in research on the association between single nucleotide polymorphisms of the DNA repair genes and resistance to platinum-based chemotherapy.
Jia WEI ; Bao-rui LIU ; Ya-ping WANG
Chinese Journal of Oncology 2006;28(3):161-163
DNA Repair
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genetics
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DNA-Binding Proteins
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genetics
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Drug Resistance, Multiple
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Drug Resistance, Neoplasm
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Endonucleases
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genetics
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Humans
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Neoplasms
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drug therapy
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genetics
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Nuclear Proteins
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genetics
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Organoplatinum Compounds
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therapeutic use
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Platinum Compounds
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therapeutic use
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Polymorphism, Single Nucleotide
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Transcription Factors
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genetics
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X-ray Repair Cross Complementing Protein 1
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Xeroderma Pigmentosum Group D Protein
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genetics
7.Stem cell-targeted therapy--a new strategy for cancer treatment.
Gang CHEN ; Li XIE ; Bao-rui LIU
Chinese Journal of Oncology 2008;30(11):801-803
ATP-Binding Cassette Transporters
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metabolism
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Adenosine
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analogs & derivatives
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therapeutic use
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Animals
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Antineoplastic Agents
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therapeutic use
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Biomarkers, Tumor
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analysis
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Cell Differentiation
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Diketopiperazines
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Heterocyclic Compounds, 4 or More Rings
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Humans
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Neoplasms
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drug therapy
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pathology
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Neoplastic Stem Cells
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cytology
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metabolism
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Protein Kinase Inhibitors
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therapeutic use
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Pyrimidinones
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therapeutic use
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Quinazolines
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therapeutic use
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Signal Transduction
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Triazines
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therapeutic use
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Wnt Proteins
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metabolism
9.Effect of comprehensive intervention on antipsychotic drug induced constipation
Ying ZHANG ; Rui FU ; Xiaoyi LI ; Lanying LIU ; Xiangdong BAO
Chinese Journal of Health Management 2014;8(3):180-183
Objective To explore the effect of comprehensive intervention on constipation caused by antipsychotic drugs.Methods Ninty patients with antipsychotic drug induced constipation who were admitted to our hospital from June 2012 to October 2013 were enrolled in this investigation and randomly assigned to the comprehensive intervention group(CIG,n=46) and the routine care group(RCG,n=44).The subjects of the RCG received routine diet and medication therapy; and those of CIG received comprehensive intervention of life style,psychological ability,cognition,nursing and traditional chinese medicine(TCM) for 3 months.Constipation symptoms scale and Patient Assessment of Constipation Quality of Life Questionnaire (PAC-QOL) were assessed before and after the intervention.Results CIG showed significant improvement in defecation difficulty,defecation force,defecation duration,frequency,abdominal distension,total symptom score,PAC-QOL,physical discomfort,psycho-social discomfort,anxiety and treatment satisfaction were(2.8±2.1),(2.2±1.6),(2.4±1.3),(2.1±1.7),(1.5±0.9),(14.0±8.1)respectively (t values were 2.629,3.818,2.328,2.593,2.578,2.913,7.499,2.570,5.012,2.249 and 12.259,respectively; all P<0.05).Conclusion Comprehensive intervention may be an effective therapy against psychiatric drug induced constipation.