1.The latest 2010 WHO classification of tumors of digestive system.
Chinese Journal of Pathology 2011;40(5):351-354
Adenocarcinoma
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pathology
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Carcinoma in Situ
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pathology
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Digestive System Neoplasms
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classification
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pathology
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Esophagogastric Junction
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pathology
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Humans
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Liver Neoplasms
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pathology
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Neoplasm Staging
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Neuroendocrine Tumors
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classification
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pathology
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Pancreatic Neoplasms
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pathology
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Precancerous Conditions
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pathology
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World Health Organization
2.Exploration of regulating blood lipids metabolism by integrative medicine.
Shan-shan LIU ; Wei WU ; Li-jin QING
Chinese Journal of Integrated Traditional and Western Medicine 2015;35(2):247-249
Hyperlipidemia is an important risk factor of cardio-/cerebrovascular disease, and reducing lipids has become an important project for itsclinical preventing and treating. Western medicine, with its confirmative efficacy and clear mechanism, has played an irreplaceable role. Along with the development of modern medicine, integrative medicine has gradually become a growing trend in regulating blood lipids metabolism. It not only could make up the insufficient power for Chinese medicine in lowering lipids, but also could reduce adverse reactions and economic costs brought by long-term administration of Western medicine. As a modern practitioner of Chinese medicine, we should keep clear that integrative medicine regulating blood lipids metabolism does not mean a simple combination of traditional Chinese medicine and Western medicine. We should treat it guided by systematic theories. We combine disease identification and syndrome differentiation, guide lipids lowering by integrative medicine including selecting Western drugs for blood lipids lowering, Chinese medical prescriptions for syndrome typing, and effective Chinese herbs based on modern pharmacologies.
Drugs, Chinese Herbal
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Humans
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Integrative Medicine
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Lipids
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blood
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Medicine, Chinese Traditional
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Risk Factors
4.Effects of Amygdalin on TNF-α and sICAM-1 of Rats with Type II Collagen-induced Arthritis
Demei LUO ; Zhigui SHAN ; Jinlian GE ; Qing LIU ; Li LUO
Chinese Journal of Information on Traditional Chinese Medicine 2015;(7):75-77
Objective To discuss effects of anti-inflammatory mechanism of amygdalin on rats with type II collagen-induced arthritis (CIA). Methods Wistar rats were randomized into normal group, model group, amygdalin group, and tripterygium group. Type II CIA rat models were established. From the 15th day after the modeling establishment, each administration group was given corresponding dose of medicine for continuous 28 days. Levels of TNF-αand sICAM-1 were detected by ELISA in serum of rats, and expression of TNF-α was detected by immuno-histochemical method. Results TNF-α positive expression in amygdalin group and tripterygium group was similar and significantly reduced compared with model group. Levels TNF-α and sICAM-1 in amygdalin group and tripterygium group significantly decreased compared with those in model group (P<0.05), without significant difference compared with normal group (P>0.05). Conclusion Amygdalin can inhibit the expression of TNF-α and levels of TNF-α and sICAM-1, in order to treat rheumatoid arthritis.
5.Preparation of andrographolide-loaded solid dispersions
Dongyuan SHAN ; Ying PEI ; Qing MENG ; Tong LI
Chinese Traditional Patent Medicine 2017;39(4):719-723
AIM To prepare the andrographolide-loaded solid dispersions.METHODS Differential scanning calorimetry (DSC) and X-ray powder diffraction (XRPD) were used for the analysis of solid dispersions previously prepared from the mixture of andrographolide and PVPK30 (1 ∶ 9) in autoclave.In addition to the evaluation index of in vitro dissolution rate,the influencing factors of pressure,temperature and reaction time were taken into consideration for the preparation optimization by Box-Behnken method.RESULTS Andrographolide was totally dispersed in solid dispersions in an amorphous state,manifesting an inhibited crystal diffraction peaks' formulation.Under the optimal conditions of 21.26 MPa for pressure,40.76 ℃ for temperature,and 1.13 h for reaction time,the in vitro dissolution rate was 85.49%.CONCLUSION After andrographolide is made into solid dispersions,its in vitro dissolution rate is obviously increased.
6.The comparison of fludarabine or antithymocyte globulin based non-myeloablative conditioning regimen for haematologic diseases with graft-versus-host disease.
Qing-Shan LI ; Xiao-Yin ZHUANG ; Ping MAO
Chinese Journal of Hematology 2011;32(8):555-557
Adult
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Antilymphocyte Serum
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therapeutic use
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Female
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Graft vs Host Disease
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prevention & control
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Hematopoietic Stem Cell Mobilization
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methods
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Humans
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Immunosuppressive Agents
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therapeutic use
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Male
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Middle Aged
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Transplantation Conditioning
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methods
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Vidarabine
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analogs & derivatives
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therapeutic use
7.Management of key diseases at emergency department of general hospitals
Yang LI ; Qing SHAN ; Kejie MA ; Houming QIAN
Chinese Journal of Hospital Administration 2014;30(11):832-834
This paper analyzed the main problems confronting support-type emergency management in general hospitals,introduced the experience and effect to strengthen the management of emergency key diseases in the hospital.The efficiency and success can be improved by implementation of institutionalized and routing management,emergency plan management based on the key diseases and strengthening the information construction and management.
8.Determination of Total Fatty Acid Esters of Chloropropanols in Edible Vegetable Oils by Gas Chromatography-Mass Spectrometry
Shan LI ; Qing YI ; Hong MIAO ; Yongning WU
Chinese Journal of Analytical Chemistry 2016;44(6):893-900
A method was established for the simultaneous determination of the total fatty acid esters of chloropropanols in edible oils by gas chromatography-mass spectrometry combined with isotope dilution technology. The samples were hydrolyzed with sodium methylate-methanol, and then purified by diatomite cartridge. After being derivatized with heptafluorobutyrylimidazole ( HFBI ), the target analytes were determined by GC-MS with the deuteriumchloropropanols esters as the internal standards. An excellent linear correlation in the range of 0. 050-2. 000 mg / L was acquired for 3-monochloropropane-1,2-diol (3-MCPD) esters, 2-MCPD esters, dichloropropan-2-ol (1,3-DCP) esters and 2,3-dichloropropan-1-ol (2,3-DCP) esters, with all the correlation coefficients (r) higher than 0. 9995. The limits of detection (LODs) for 3-MCPD esters, 2-MCPD esters, 1,3-DCP esters and 2,3-DCP esters were 0. 015, 0. 015, 0. 030, and 0. 030 mg / kg, respectively, and the limits of quantitation (LOQ) were 0. 050, 0. 050, 0. 100, and 0. 100 mg / kg, respectively. The average spike recoveries of the four kinds of chloropropanols esters in blank extra virgin olive oil matrix were typically in a range of 87. 0% -110. 5% with the relative standard deviations (RSDs) less than 10. 1% . The detection rates of 3-MCPD esters, 2-MCPD esters, 1,3-DCP esters and 2,3-DCP esters in 74 edible oil samples were 94. 6% , 63. 5% , 5. 4% , and 0% , respectively. The contamination levels of 3-MCPD esters, 2-MCPD esters and 1,3-DCP esters were in the range of not detected (ND) to 10. 646 mg / kg, ND to 3. 617 mg / kg and ND to 0. 089 mg / kg, respectively. This method is accurate and rugged for the simultaneous determination of total fatty acid esters of chloropropanols in edible vegetable oils.
9.The value of isotropic scanning and lung care software of 16-slice spiral CT in the diagnosis of solitary pulmonary nodules
Rui XU ; Jian-Long LI ; Cheng XIANG ; Yu-Qing SHAN ;
Cancer Research and Clinic 2006;0(12):-
Objective To evaluate the diagnostic evaluation of isotropic scanning and Lung Care soft- ware in solitary pulmonary nodules,and to improve the diagnostic accuracy.Methods 52 patients suffered from SPN were included in our study.Two experts in CT analyzed the films.First,they read the axial images and made diagnosis.Then isotropic scanning and lung care software approaches were used on 16 spiral CT and another analysis were made again.The results were compared with pathological diagnosis respectively. Results Spiculated sign,lobulated sign,vessel convergence were found more on isotropic scanning approach, that had significant difference with axial images analysis(P
10.Comparison of cognition and attitude towards the elderly family nursing among college students and nurses
Weiying SHAN ; Qing LI ; Shufeng ZHANG ; Ying YANG ; Fei QI
Chinese Journal of Practical Nursing 2010;26(22):67-70
Objective To investigate the cognition and attitude towards the elderly family nursing among nurses and college students in Chengde, and analyze its influencing factors. Methods A total of 1000 college students and nurses in Chengde were investigated by self-designed questionnaire about their cognition and attitude to elderly family nursing. Results Nurses' cognition and attitude towards the elderly family nursing was better than nursing college students, medical students were better than non-medical students; and there was no statistical significance about their expectation for government's senior citizen service among different groups. Conclusions More attention should be paid to family members' attitudetowards the elderly home care, and should strengthen the elderly family care through various way.