2.Analysis of features on prolonged central serous chorioretinopathy by optical coherent tomography
Hui-Qin, WU ; Hui-Qin, LU ; Hong-Bing, ZHANG
International Eye Science 2015;(7):1261-1262
AlM:To investigate the features on prolonged central serous chorioretinopathy ( CSCR ) by optical coherent tomography ( OCT ) and to provide the basis of deciding the pathogenetic condition and prognosis. METHODS: Eighty - five patients who had been diagnosed with CSCR were grouped by suffering time as below: 32 patients suffered longer than 6mo as the prolonged and 53 patients with CSCR cured within that time. The imaging features of OCT were compared between the above groups.RESULTS:The incidence rate of neuroepithelial serous detachment extent above 500μm associated with pigmentary epithelial detachment in suffering eye and pigmentary epithelial damage in contralateral eye was significantly different between two groups. However, the incidence rate of neuroepithelial serous detachment extent above 4 000μm was not significant difference.CONCLUSlON:OCT could display clearly the change of every layer of retina with simplicity and visibility, which supplies us a new horizon to diagnose and trace CSCR. We could decide the pathogenetic condition and prognosis in accordance with the features of OCT, to provide references for the diagnosis and treatment of CSCR.
3.Self-blood therap for 62 cases of senile skin pruritus.
Hui XIAO ; Jian QIN ; You-Xing ZHANG
Chinese Acupuncture & Moxibustion 2013;33(8):757-758
Acupuncture Points
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Aged
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Aged, 80 and over
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Bloodletting
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Female
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Humans
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Middle Aged
;
Pruritus
;
therapy
5.Medical monitor system based on network communications
Mingyan QIN ; Hui YU ; Lixin ZHANG
Chinese Medical Equipment Journal 1989;0(01):-
In this paper,the development trend of medical monitor system is analyzed.The portable trend and network function become more and more popular among all kinds of medical monitor devices.The architecture of medical network monitor system is provided: pocket medical monitor devices based on embedded platform is developed to interact with center database on networks;the telecommunication interface based on 802.11b/g and CDMA is designed to rebuild and extend the functions of traditional imaging devices(ultrasonic?CT?MRI) and the implementation details of terminal,monitor center software,distributed database and two kinds of medical information terminal are especially discussed;distributed medical database is designed for hospital center according to DICOM information model and HL7 standard;hand terminal based on WINCE is developed for nurse's routine care and doctor's auxiliary diagnosis.
6.Clinical observation of ruangan suopi tablet in treating chronic hepatitis B caused liver cirrhosis.
Jia-fu LI ; Hui-qin ZHANG ; Peng-hui SHI
Chinese Journal of Integrated Traditional and Western Medicine 2002;22(3):188-189
Adult
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Drugs, Chinese Herbal
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therapeutic use
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Female
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Hepatitis B, Chronic
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complications
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drug therapy
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Humans
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Liver Cirrhosis
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drug therapy
;
etiology
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Male
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Middle Aged
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Phytotherapy
;
Tablets
7.EP in the plasma of artery in healthy volunteers after exposure to high altitude in short time.
Fen GAO ; Hui-qin MAO ; Lin-bin ZHANG
Chinese Journal of Applied Physiology 2006;22(3):315-321
Adult
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Altitude
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Arteries
;
metabolism
;
Calcitonin Gene-Related Peptide
;
blood
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Humans
;
beta-Endorphin
;
blood
8.The construction of cell-penetrating peptide R8 and pH sensitive cleavable polyethylene glycols co-modified liposomes.
Li ZHANG ; Yang WANG ; Hui-le GAO ; Qin HE
Acta Pharmaceutica Sinica 2015;50(6):760-766
The purpose of the study is to construct R8 peptide (RRRRRRRR) and pH sensitive polyethylene glycols (PEG) co-modified liposomes (Cl-Lip) and utilize them in breast cancer treatment. The co-modified liposomes were prepared with soybean phospholipid, cholesterol, DSPE-PEG2K-R8 and PEG5K-Hz-PE (pH sensitive PEG). The size and zeta potential of Cl-Lip were also characterized. The in vitro experiment demonstrated that the Cl-Lip had high serum stability in 50% fetal bovine serum. The cellular uptake of Cl-Lip under different pre-incubated conditions was evaluated on 4T1 cells. And the endocytosis pathway, lysosome escape ability and tumor spheroid penetration ability were also evaluated. The results showed the particle size of the Cl-Lip was (110.4 ± 5.2) nm, PDI of the Cl-Lip was 0.207 ± 0.039 and zeta potential of the Cl-Lip was (-3.46 ± 0.05) mV. The cellular uptake of Cl-Lip on 4T1 cells was pH sensitive, as the cellular uptake of Cl-Lip pre-incubated in pH 6.0 was higher than that of pH 7.4 under each time point. The main endocytosis pathways of Cl-Lip under pH 6.0 were micropinocytosis and energy-dependent pathway. At the same time, the Cl-Lip with pre-incubation in pH 6.0 had high lysosome escape ability and high tumor spheroid penetration ability. All the above results demonstrated that the Cl-Lip we constructed had high pH sensitivity and is a promising drug delivery system.
Animals
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Cell Line, Tumor
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Cell-Penetrating Peptides
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chemical synthesis
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chemistry
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Cholesterol
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chemistry
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Drug Delivery Systems
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Liposomes
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Mice
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Oligopeptides
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chemical synthesis
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chemistry
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Particle Size
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Phospholipids
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chemistry
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Polyethylene Glycols
9.Practice of Teaching Reform in Sanitary Reconnaissance of Water Source
Hai-Hong QIN ; Hui SHEN ; Zhe ZHANG ; Min LI ;
Chinese Journal of Medical Education Research 2006;0(10):-
According to the requirement of simulated actual combat,based on the traditional contents of sanitary reconnaissance of water source,this paper introduced some practical knowledge and skills in drinking water under emergency,including water source search,utilization,drinking principles and some measures to reduce the loss of body water.These practices enriched and consum- mated the subject of sanitary reconnaissance of water source.
10.Study on Biologic-Ecological Restoration for Eutrophication Water
Xing-Bi DAI ; Hui WANG ; Qin ZHANG ; Al ET ;
Journal of Environment and Health 2007;0(10):-
Objective To find the dominant bacteria in mountain-lake water which can inhibit the alga growth by separation, culture,identification.Methods The samples from the lake in Simian Mountain area,Chongqing were collected.Bacteria- increasing culture,separation and identification were conducted to choice the dominant bacteria.With the dominant bacteria,the ecological restoration was conducted in the eutrophicated water in laboratory,the growth of alga was observed and the water quality was determined.Results Citrobacter freundi,Pseudomonas mendocina,Aeromonas veronii,Achromobaeter xylosoxidans were the dominant bacteria in the lake in Simian Mountain area,Chongqing.Compared with the blank water eontrol,the algae growth speed was slower,COD_(Mn)was 7.1 and 7.4 mg/L respectively,the chroma was both 20 degree in the experimental water samples with Citrobacter freundii and Pseudomonas mendocina.Conclusion The algae inhibitory action of Citrobacter freundii and Pseudomonas mendocina in the mountain lake water is obvious.