1.Value of Reticulated Platelet Counts in Diagnosis and Treating Idiopathic Thrombocytopenic Purpura
Journal of Applied Clinical Pediatrics 1993;0(03):-
Objective To evaluate the changes of reticulated platelets (RP)in diagnosis and treatment of idiopathic thrombocytopenic purpura (ITP). Methods RPs were measured by flow cytometry and the percentage and absolute counts of RPs were calcula- ted in ITP group,non-ITP group and control group.Results Compared with control group,ITP group had a significantly high percentage and low absolute counts of RPs (P
4.Case of facial paralysis.
Sheng-Qiang WANG ; Jian-Ping WANG
Chinese Acupuncture & Moxibustion 2014;34(7):678-678
5.Treatment of Lisfranc joint injury with the operation of the Kirsehnerwlres and screw
Yabin ZHU ; Qiang LI ; Jian WANG
Clinical Medicine of China 2016;32(2):164-167
Objective To summarize the clinical experience of operation treatment of Lisfranc fracture dislocation,and evaluate its clinical effect.Methods Thirty-nine patients with Lisfranc joint injuries (46 sides) were managed with open reduetlon as well as internal fixation with serews and Kirsehnerwlres.Results All the patients were followed up from12.0 to 42.0 months,the average was (21.1 ± 1.8) months.Evaluated the clinical effect according to the American Orthopaedic Foot and Ankle Society (AOFAS) midfoot score standard,there were 29 cases of excellent,8 cases of good,and 3 cases of aceeptable.Conclusion By Kirschner wire combining with screw fixation,open reduction and internal fixation may achieve satisfactory clinical results for the treatment of Lisfranc joint injurie.The operation is simple and fast,small trauma,less complications and can obtain good effects.
6.Minimally Invasive Surgery of Breast Fibroadenoma
Hongying WANG ; Qiang ZOU ; Jian ZHOU
Chinese Journal of Minimally Invasive Surgery 2001;0(05):-
Ojective To evaluate the clinical application of ultrasound-guided Mammotome system to the treatment of patients with breast fibroadenoma. Methods The minimally invasive operations for 53 breast fibroadenoma in 43 patients were performed by ultrasound-guided Mammotome system, and the therapeutic efficacy of Mammotome system was evaluated. Results 53 lesions (0.6cm~2.2cm) in 43 patients with breast fibroadenoma were completely excised by the Mammotome system. The average incisions were 17 times and the mean operative time was 31 min. All the operations were successfully accomplished without serious complication. The length of incision was only 3 mm. And no recurrence was found by physical examination and B-ultrasonography in 15 patients(21 lesions) during follow up period for 6~21(13.5?4.0) months. Conclusions Mammotome system is simple and effective technique with minimal invasion for the excision of small breast fibroadenoma.
8.Transartenal chemoembolization and portal vein chemotherapy for hepatocellular carcinoma with portal vein tumor thrombosis
Jian WANG ; Fare SUN ; Yunlong GUI ; Qiang LI
Chinese Journal of General Surgery 1993;0(01):-
Objective To explore the efficacy of postoperative transarterial chemoembolization (TACE) and portal vein chemotherapy (PVC) for hepatocellular carcinoma (HCC) patients complicated with portal vein tumor thrombus (PVTT). Methods One hundred and eleven HCC patients with PVTT were randomly divided into three groups receiving respectively tumor resection only ( group A) , resection plus TACE ( group B) , and resection plus TACE and PVC ( group C). Results (1) Group B had significantly lower recurrence rates at 0. 5- and 1-year, and higher survival rates at 0. 5-year compared with group A (P
10.Clonality analysis for differentiating multicentric origin and intrahepatic metastasis in multiple hepatocellular carcinomas
Jian WANG ; Yan SUN ; Hong ZHENG ; Yunlong CUI ; Qiang LI
Chinese Journal of Hepatobiliary Surgery 2010;16(12):906-909
Objective To explore the differential diagnostic significance of clone analysis for multicentric occurrence (MO) and intrahepatic metastasis (IM) in hepatocellular carcinomas (HCCs).Methods Loss of heterozygosity (LOH) and microsatellite instability (MSI) were analyzed by microsatellite polymorphism test and the integration sites of HBV were assessed by Southern blot in each nodule of the HCCs. The clonalities were then compared between each nodule of the same patient and the diagnosis of MO or IM was concluded. Finally, the results based on clonality analysis were compared with those according to clinicopathological and imaging data. Results According to the results of LOH and MSI in 79 nodules and nontumorous tissue from 35 cases of mutiple HCCs, 5 (14.3%)and 29 cases (82.9 %) were divided into MO and IM, respectively. Both MO and IM presented simultaneously in 1 patient (2.9%). The integration sites of HBV could be analyzed in 77 nodules from 34 multiple HCCs. Among them, 6 (17. 6%) and 27 cases (79.4%) were divided into MO and IM, respectively. Both MO and IM presented simultaneously in 1 patient (2.9%). The classification results of microsatellite polymorphism test and HBV integration sites analysis demonstrated a significant positive correlation (rs = 0.909, P<0.001). Nevertheless, neither the classification of microsatellite polymorphism test nor that of HBV integrate sites analysis was correlated with the discrimination according to clinicopathologic and imaging data (rs=0. 133, P=0. 468, rs =0. 262, P=0. 155, respectively). Recurrence in patients in the MO group occurred significantly later than that in IM cases who were diagnosed by clonality analyses (P=0. 001). Conclusion The clonality analysis based on the results of LOH and MSI or assessments of HBV integrate sites is useful for the differential diagnosis of MO and IM and their treatment and prognosis.