Under the current epidemiological conditions as found in Korea, and considering the limited funds available for the malaria project, passive case detection proved to be the only practical mechanism to obtain reliable data required for the delimitation of malarious areas. The malaria map of the country was completed at the end of 1965. The high SPRs found among the blood smears reported by the PCD undts are due to the fact that the Korean farmer is able to recognize the clinical symptoms of the disease. The "fever case" reports are therefore actually "suspect malaria case" reports. The consistently high SPR has resulted in the detection of a large number of parasite carriers with the number of smears to be examined being reduced to a minimum. Although the medical group gave an important contribution to the success of the PCD service in Korea, the number of medical and public health facilities in the rural areas are still too small. This made it necessary to obtain the collaboration of laymen groups like school teachers, village chiefs etc., and their participation largely contributed to the success of the present programme. The degree of collaboration by the PCD units is higher in the more malarious areas. As no form of encouragement e.g., a reporting fee, has been given to these laymen during the past few years it becomes increasingly more difficult to maintain their active co-operation. It is felt that through passive case detection alone it will not be possible to collect adequate information to provide the proof for the complete interruption of transmission.
parasitology-protozoa ; Plasmodium vivax ; malaria ; diagnosis ; epidemiology

The authors carried out two series of field test to determine the basic lines of DDT and Dieldrin susceptibility of Anopheles sinensis at Andong(1961) and Yoju(1962), where malaria endemicity is relatively high in Korea. Tests were performed in accordance with the standard method established by the World Health Oraganization(1960). The results were summarized as follows: The LC-50 of DDT for A. sinensis caught at Andong as 1.5 %, while for the same species in Yoju was 1.3 %. The LC-50 of Dieldrin for A. sinensis caught at Andong was 0.075 %, while the LC-50 for the same species at Yoju was 0.07 %. These results therefore indicate Anopheles sinensis, as the malaria vector species in Korea, is susceptible to DDT and Dieldrin.
parasitology-protozoa-Plasmodium vivax ; chemotherapy-malaria ; Anopheles sinensis ; DDT ; Dieldrin

The usefulness of malaria diagnosis by Plasmodium falciparum-GDH (NADP+), obtained by affinity chromatography, is demonstrated in ELISA assays, testing IgG antibodies against GDH (NADP+) from patients with acute malaria, who have had two or more episodes of malaria, or from sera of hyperimmune patients. GDH (NADP+) thermal stability was demonstrated in a high heat resistance assay. The immunofluorescence assay demonstrated that anti-culture (P. falciparum) supernatant serum and anti-GDH (NADP+) of Proteus spp, recognized epitopes in Venezuelan isolates, and Colombian and Brasilian malarial strains. The antigen is soluble, with high specificity, is a potent immunogen and is thermoresistant.
parasitology-protozoa ; antigen ; enzymes ; glutamate dehydrogenase ; malaria ; diagnosis ; Plasmodium berghei ; Plasmodium cathemerium ; Plasmodium falciparum ; Plasmodium vivax ; enzyme-linked immunosorbent assay

On epidemiological grounds, Anopheles sinensis has been suspected for many years to be the malaria vector in Korea. Of 7,517 dissections of A. sinensis, one specimen was found for the first time in Korea naturally infected with sporozoites in August 1962. Experimental infection of A. sinensis with Plasmodium vivax had been successfully conducted at earlier date.
mosquito-parasitology ; malaria-vector ; arthrooda-Anopheles sinensis ; protozoa-Plasmodium vivax ; epidemiology-Korea