1.Tear and ocular surface profile in adult anophthalmic sockets
Marie Christine T. Marcelo ; Joseph Maylem Ranche ; Mary Rose Pe-Yan ; Prospero Ma. C Tuañ ; o ; Felice Katrina Trio-Ranche
Philippine Journal of Ophthalmology 2012;37(2):104-110
Objective:
To determine the tear and ocular surface profile of the anophthalmic socket in relation to the contralateral
normal eye.
Methods:
Twenty-five adult patients with unilateral anophthalmic sockets were included into the study. They were
at least 2 months post-enucleation or post-evisceration and without any topical medications on the anophthalmic
socket and control eye for at least 2 weeks. Assessment was performed using the following parameters: (1) meibomian
gland evaluation, (2) ocular surface staining, (3) degree of conjunctival inflammation, (4) Schirmer I and II, and (5)
conjunctival impression cytology.
Results:
Mucoid discharge (52%) was the most common complaint in anophthalmic sockets, followed by itchiness
(40%), tearing (36%), and dryness (4%). Compared to control eyes, the anophthalmic sockets had more pronounced
and statistically significant lid wiper epitheliopathy, conjunctival staining, and bulbar inflammation. Meibomian
gland dysfunction, Schirmer I and II, and conjunctival impression cytology showed no difference between the
2 groups. There was a correlation between the symptoms complained and the ocular staining patterns of the
anophthalmic sockets.
Conclusion
Anophthalmia predisposes to various ocular surface problems, such as a change in the composition
of tears, specifically an increase in the mucin component and a decrease in the aqueous and lipid components,
resulting to increased tear viscosity.
onjunctiva
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Cytology